Clinical trials: Fatigue in Multiple Sclerosis
Multiple Sclerosis
Trunk Stability, Balance, and Fatigue in Minimally to Moderately Disabled People With Multiple Sclerosis
The goal of this observational study is to investigate the relationship between trunk stability and balance, mobility, upper limb performance, and fatigue in people with multiple sclerosis (MS) with minimal to moderate disability…
- Trial name
- NCT07370935
- Testing
- Measurements
- Volunteers
- 64 people
- Sponsor
- Cappadocia University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Fatigue in Multiple Sclerosis
MS Fatigue and tDCS on Fatigue in Multiple Sclerosis
The available therapeutic strategies for Multiple Sclerosis (MS)-related symptoms are usually faced with limited efficacy and numerous side effects.
- Trial name
- MSfatDCS (NCT05890885)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Progressive Multiple Sclerosis
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
The study is being done to determine if treatment with a novel form of light therapy is tolerated in patients with progressive multiple sclerosis.
- Trial name
- NO-FATIGUE (NCT06261528)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Multiple Sclerosis, Fatigue
Effects of Laughter Yoga on Fatigue, Sleep Quality and Psychological Well-Being in Patients With Multiple Sclerosis: A Randomized Controlled Trial
This study is planned to evaluate the effects of laughter yoga applied to patients with multiple sclerosis on fatigue, sleep quality and psychological well-being.
- Conditions
- Multiple Sclerosis, Fatigue, Sleep Quality, Psychological Well-being
- Trial name
- NCT06783413
- Testing
- Intervention group (Laughter Yoga), Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tokat Gaziosmanpasa University
Multiple Sclerosis
Effects of Motor Imagery and Action Observation in People With Multiple Sclerosis
It was planned to examine the effects of motor imagery and action observation applied in addition to standard rehabilitation in people with multiple sclerosis on walking, fatigue, and trunk control.
- Trial name
- NCT05377476
- Testing
- Motor Imagery training, Action Observation training, standard rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Multiple Sclerosis, Healthy
Walking Fatigability and Brain Activity in People With Multiple Sclerosis
Walking fatigability is a motor impairment happening in approximately 43.5% of people with multiple sclerosis (pwMS). Walking fatigability is defined as a decrease in 10% of distance walked, comparing the first minute with the…
- Trial name
- NCT06672484
- Where
- 3 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Fatigue, Multiple Sclerosis
Observational Study of the Effect of Ozanimod on Fatigue in Multiple Sclerosis Patients
Multi-center observational study to assess the short-term response of multiple sclerosis (MS) patients initiated on Ozanimod with respect to fatigue.
- Trial name
- NCT05319093
- Testing
- Ozanimod
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Multiple Sclerosis, Fatigue
Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
This prospective case series will use mixed methods to examine the feasibility, acceptability, and initial effects of three telehealth cognitive behavioral therapy components (relaxation training, behavioral activation, cognitive…
- Trial name
- NCT05848323
- Testing
- 4-week Relaxation Training, 4-week Behavioral Activation, 4-week Cognitive Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Washington
Multiple Sclerosis, Pain
Usability of the MeTime MS App
The Me Time MS Application was designed to enable self-administration of acupressure. Two forms of acupressure - either "relaxing" or "stimulating" protocols - are administered through the Me Time MS app.
- Conditions
- Multiple Sclerosis, Pain, Fatigue Symptom
- Trial name
- NCT07123272
- Testing
- Self-guided smartphone application for relaxing acupressure, Self-guided smartphone application for stimulating acupressure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Multiple Sclerosis, Fatigue Syndrome, Chronic
Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care
The main objective of the MS Boost study is to demonstrate the superiority of MSCopilot Boost over standard practice in reducing the impact of fatigue on Patients with Multiple Sclerosis (MS).
- Trial name
- MSBoost (NCT06386133)
- Testing
- MS Boost, Standard of care
- Volunteers
- 208 people
- Sponsor
- Ad scientiam
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
Sexual Dysfunction in Women With Multiple Sclerosis (MS)
Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Fatigue in Multiple Sclerosis, Sexual Disfunction
- Trial name
- MS (NCT07193823)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ege University
Multiple Sclerosis
Comparing the Acute Effects of Different Exercise Approaches in Patients With Multiple Sclerosis
Multiple Sclerosis (MS) is the second most common neurological disorder in young adults after trauma. Treatments developed today can slow progression and reduce symptoms.
- Trial name
- NCT06721416
- Testing
- Traditional Aerobic Exercise, VR Based Aerobic Exercise, Conventional Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Acibadem University
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Multiple Sclerosis
Yoga in Multiple Sclerosis Patients
Objective The objective of this study will be to compare the effects of an eight-week Yin-based yoga program and conventional physiotherapy on fatigue, balance, gait, and quality of life in individuals with Multiple Sclerosis…
- Trial name
- NCT07155642
- Testing
- yoga, conventional physiotheraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Rumeli University
Fatigue in Multiple Sclerosis
Testing the Effects of Methylphenidate on Multiple Sclerosis
Up to 95% of individuals with Multiple Sclerosis report experiencing cognitive fatigue, characterized by a lack of energy, feelings of exhaustion, an the perception that one is unable to partake in daily activities.
- Trial name
- NCT02286557
- Testing
- Methelphenidate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Effect of Resistance Training on Psychophysiological Indicators in People With Multiple Sclerosis
This randomized controlled trial aims to investigate the effects of a supervised resistance training program on plasma levels of Brain-Derived Neurotrophic Factor (BDNF) and irisin in individuals diagnosed with multiple sclerosis…
- Trial name
- NCT07118514
- Testing
- Progressive Resistance Training, Stretching and Relaxation Activities
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- State University of Maringá
Multiple Sclerosis
Effects of a Circuit Training on Balance in Persons With Multiple Sclerosis
The aim of the study is to evaluate the effects of a circuit training rehabilitation program on the perceived impact of fatigue in daily life situations and on gait and balance.
- Trial name
- NCT04006613
- Testing
- Circuit Training, Usual Care
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Fatigue in Multiple Sclerosis, Multiple Sclerosis
Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the Disease
The study is focused on several independent quantifiable biomarkers (sNfL, sGFAP, mitochondrial activity, genetics and fatigue tests) to obtain more detailed information about MS and its progression.
- Conditions
- Fatigue in Multiple Sclerosis, Multiple Sclerosis, Neurofilaments Light Chains, GFAP
- Trial name
- MITOFATIGUE (NCT07025122)
- Where
- Slovakia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Martin
Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue
The Effect of Task-Oriented Training and Virtual Reality Training on Balance, Gait and Fatigue in Individuals With Multiple Sclerosis
Introduction: Multiple sclerosis (MS) is a chronic disease of the central nervous system. Task-focused training is an approach that relies on multiple repetitions of motor performance.
- Conditions
- Multiple Sclerosis, Balance Impairment, Gait Disorders, Fatigue, Multiple Sclerosis Bening, Multiple Sclerosis Relapsing Remitting
- Trial name
- NCT07000968
- Testing
- Virtual Reality Training Group, Task-Oriented Training Group, Conventional Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Inonu University