Clinical trials: Fatty Acids
Healthy
Effects of Fish Oil and Red Wine on Oxidative Stress Biomarkers
The American Heart Association and the American College of Cardiology (AHA/ACC) recently encouraged "increased consumption of omega-3 fatty acids in the form of fish or capsule form (1 g/day) for risk reduction" and stated that…
- Trial name
- NCT00682318
- Testing
- Fish Oil, Safflower Oil, Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carsten Skarke, MD
Inflammation, Malnutrition
Effects of Camelina Sativa Oil in Free-living Older Adults
The present study aims at evaluating the anti-inflammatory effects of a novel food in older adult volunteers. Briefly, this randomized, double-blind and placebo-controlled study is performed on 91 apparently healthy older adults…
- Conditions
- Inflammation, Malnutrition, Hyperglycemia, Dyslipidemias
- Trial name
- NCT04965948
- Testing
- Novel food snack
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Obesity
Exercise Dose Response for Improving Insulin Sensitivity
Many of the beneficial metabolic effects of endurance exercise training are not due to adaptations to weeks, months, or even years of training, but rather much is due to the response to the most recent exercise session(s).
- Trial name
- NCT01452035
- Testing
- Exercise
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Executive Function
Fatty Acids and Executive Function Development in 7-12 Year Olds
Purpose: To examine the effect of the omega-6 to omega-3 fatty acid ratio on age-related changes in executive functions in children and older adults. Participants: Eighty-four typically-developing 7-to 12-year-old children.
- Trial name
- NCT02199808
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hypogeusia
Free Fatty Acids: Short Exposure Study
This study will examine whether or not short, daily exposures change a person's ability to detect free fatty acids in a solution by its taste. Repeated exposure should improve a person's ability to detect free fatty acids.
- Trial name
- NCT01686113
- Testing
- NEFA, Sucrose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetes Mellitus, Type 2, Insulin Resistance
Production of Free Fatty Acids From Blood Triglycerides
The overall hypothesis of these studies is that circulating triglycerides, coming primarily from fat in the diet, are an important source of free fatty acids.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Dyslipidemias
- Trial name
- NCT00911482
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vegetarian Diet
Effects of the Consumption of a Supplement Rich in Docosahexaenoic Acid (DHA) From Algae
Vegetarian diets are increasing worldwide. To prevent nutritional deficiencies, supplementation with nutrients that are only present in animal food can be needed.
- Trial name
- NCT04278482
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Dyslipidemia, Diabetes
Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors
Fructose-containing sugars have been implicated in the epidemics of obesity, diabetes and related cardiometabolic disorders. This view is supported by lower quality evidence from ecological observations, animal models, and select…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT02716870
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pharmacokinetics
Pharmacokinetics of Two Fatty Acid Ketone Esters
Randomized, cross over pharmacokinetic study of a novel ketone di-ester and C6 ketone di-ester in ready to drink beverage matrices.
- Trial name
- NCT05686083
- Testing
- C6 ketone di-ester, Novel ketone di-ester
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BHB Therapeutics, Ireland LTD
Emotions, Stress
The Role of Short Chain Fatty Acids in Microbiota-gut-brain Axis
The role of short chain fatty acids (SCFA) in the microbiota-gut-brain axis is examined in a sample of healthy volunteers. SCFA are the major products of bacterial fermentation of dietary fiber in the colon, and are hypothesised…
- Conditions
- Emotions, Stress, Fear
- Trial name
- SCFA-AP (NCT03688854)
- Testing
- SCFA mixture
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy
Influence of Improved Formula on Fatty Acids and Mineral Metabolism in Infants
The purpose of this study is to determine whether different content of β-palmitate will cause significant differences on Fatty Acids and Mineral Metabolism in Infants
- Trial name
- NCT02587702
- Testing
- β-Palmitate Content, β-Palmitate Content Naturely in Human Milk
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beingmate Baby & Child Food Co Ltd .
Premenstrual Syndrome
Investigation of Krill Oil in Women with Premenstrual Syndrome
In this study the effects of different dosages and preparations of krill oil in comparison to placebo on symptoms of premenstrual syndrome in healthy, female adults will be assessed.
- Trial name
- NCT06584669
- Testing
- Krill oil
- Where
- Germany
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Aker BioMarine Human Ingredients AS
Non-Alcoholic Fatty Liver Disease, Obesity
Direct Versus Indirect Effect of Amino Acids on Hepatokines
Liver hormones are key metabolic regulators and increased in metabolic diseases, including fatty liver disease. The underlying mechanisms driving the elevated levels are currently unknown and presents a major challenge in…
- Trial name
- Diaakine (NCT06240039)
- Testing
- Evaluating the acute effect of an amino acid infusion with and without a concomitant infusion of the somatostatin analogue octreotide to eliminate endogenous production of glucagon
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Exercised Induced Asthma, Asthma
The Effects of Prebiotics on Gut Bacterial Parameters, Immune Function & Exercise-Induced Airway Inflammation.
The current study aims to explore the role of prebiotic supplementation in adults with and without Asthma/Exercise-Induced Bronchoconstriction (A/EIB).
- Trial name
- NCT02872675
- Testing
- HOST-DM059, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Strength, Body Composition
Omega-3 Fatty Acid Supplementation to Enhance Performance
The goal of this intervention study is to determine if omega-3 fatty acid supplementation as compared to placebo improves performance in track and field athletes. The main questions it aims to answer are: 1.
- Conditions
- Strength, Body Composition, Muscle Soreness
- Trial name
- FO n-3 (NCT05924139)
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Baylor University
Focus: Nutritional Requirements for Infants
Assessment of Arachidonic Acid Supplementation in Infant Formula on the Immune Response of Infants
The immune system of newborn infants is immature with low activity of both innate and acquired immune reactions. Early nutrition has an impact on early immune responses.
- Trial name
- NCT02092857
- Testing
- Arachidonic acid (25 mg/100 kcal ), Arachidonic acid (34 mg/100 kcal)
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Klinefelter Syndrome
Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome
This study will learn more about how the body uses energy. Usually, the body uses sugars as energy first and then fats are used when the sugar stores are gone. Some people have trouble using fats as energy.
- Trial name
- NCT05498090
- Testing
- Fenofibrate 145 mg
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fibromyalgia, Systemic Lupus Erythematosus
Membrane Polyunsaturated Fatty Acid Content in Fibromyalgia and Systemic Lupus Erythematosus (SLE)
Polyunsaturated omega-3 fatty acids (ω3 PUFAs) are essential nutrients. Studies indicate that the incidence of Major Depression (MD) is inversely related to the consumption of fish (which are rich in ω3-PUFAs) and to the…
- Trial name
- NCT01460680
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Metabolic Health
ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks
The purpose of this study is to determine the impact of real-world shiftwork on metabolic flexibility.
- Trial name
- COMET (NCT05820490)
- Testing
- Whole Room Calorimeter, Mixed-Meal Tolerance Test (MMTT), Core Body Temperature
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Diabetes, Hypertension
FFA Hypertension and Inflammation in Lean and Obese Subjects
Although a large number of obese patients develop high blood pressure, the cause is unknown. The purpose of this study is to look at the effect of high fatty acids (a type of fat) in the development of high blood pressure in…
- Conditions
- Diabetes, Hypertension, Obesity
- Trial name
- FFAADA (NCT00721617)
- Testing
- Intralipid 20%, Normal Saline, Oral fat load
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University