Clinical trials: Fatty Acids
Gene Expression
Impact of a Short-Term High Fat or Low Fat Diet on Intestinal Genes Expression Involved in the Cholesterol and Fatty Acid Metabolism
Dietary fat has been shown to modulate cholesterol and fatty acids homeostasis and several lines of evidence suggest that this effect is associated with changes in the regulation of different genes at the intestine level involved…
- Trial name
- DGENES (NCT01806441)
- Testing
- 3-days high fat diet, 3-days low fat diet
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Laval University
Sleep, Sleep Deprivation
Sleep Loss and Glucose Metabolism in People With Family History of Type 2 Diabetes.
The use of sugar and starch-like foods for energy (carbohydrate metabolism) changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the carbohydrate metabolism…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00721019
- Testing
- 5-hour bedtime, 8.5-hour bedtimes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Healthy, Uveitis
Vitamin and Unsaturated Fatty Acid Supplements in Healthy and Uveitis Human Subjects
The goal of this clinical trial is to learn if dietary supplements containing vitamin and unsaturated fatty acid works to intervene T cell inflammatory factor expression in patients with uveitis and healthy subjects in adults.
- Conditions
- Healthy, Uveitis, Autoimmune Diseases
- Trial name
- NCT06491979
- Testing
- Vitamin A treatment, Monounsaturated fatty acid mixture, Polyunsaturated fatty acid mixture
- Where
- China
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Hypertension, Diabetes
Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)
The purpose of this study is to see if salsalate, an Nuclear factor-kappaB (NF-κB) mediated inflammation inhibitor, or carvedilol, an α- and β-blocker, will protect against free fatty acid induced hypertension, insulin…
- Trial name
- FFAADA (NCT02406586)
- Testing
- Salsalate, Carvedilol, Intralipid 20%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Emory University
Intermittent Fasting
Ramadan Fasting, Microbiota and FABP4
This study, which aims to examine the effect of Ramadan fasting on intestinal microbiota composition and FABP4, was designed as a quasi-experimental study.
- Trial name
- NCT06105372
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Okan University
Non-alcoholic Fatty Liver Disease (NAFLD)
Elucidating Hepatic Metabolism in Non-alcoholic Fatty Liver Disease
The goal of this observational, cross-sectional, case-control clinical study is to investigate the metabolic adaptations underlying the progression of nonalcoholic fatty liver disease (NAFLD), and to test the hypothesis that…
- Trial name
- ECHO (NCT06942312)
- Testing
- Ketoisocaproic acid breath test, Ammonium Chloride, Bicarbonate de sodium
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Exercise Training, Dietary Supplements
Fish Nutrient Supplementation in High-intensity Functional Training
Nowadays, many persons who exercise consume dietary supplements. Previous scientific studies have found that protein supplementation increases muscle mass when combined with an exercise program.
- Trial name
- NCT05402527
- Testing
- Fish nutrients, Whey protein, Maltodextrin
- Where
- Greece
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Healthy
Effects of Omacor and Aspirin on Platelet Function
Omacor (now Lovaza) is a pharmaceutical omega-3 fatty acid product. Omega-3 fatty acids can affect blood clotting by altering the function of the blood platelets. Aspirin can do the same.
- Trial name
- NCT00688961
- Testing
- Aspirin, omega-3 acid ethyl esters
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sanford Research
Polycystic Ovary Syndrome
Role of Insulin Action and Free Fatty Acids in Hyperandrogenism of Women With Polycystic Ovary Syndrome
The investigators hypothesis is that free fatty acids (FFA) accumulation in non fatty tissues would lead to insulin resistance and hyperandrogenism in PCOS women.
- Trial name
- NCT01019356
- Testing
- Rosiglitazone, Acarbose
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Jean-Patrice Baillargeon
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dyslipidemia
Effect of Omega -3 Fatty Acids Supplements and Plant Sterol Enriched Food in Dyslipidemic Adults
The incidence of chronic degenerative diseases, especially cardiovascular disease (CVD), is high world over and especially in India. High blood cholesterol and triglyceride levels are known to be important risk factors for CVD.
- Trial name
- NCT00422266
- Testing
- Omega 3 fatty acids and plant sterol enriched drink, Omega 3 fatty acids and plant sterols
- Where
- India
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Centre for Chronic Disease Control, India
Obesity, Diabetes
Gut Microbiota, Short Chain Fatty Acids, and Adiposity Across The Epidemiological Transition
The objective of this study is to define associations between gut microbiota, SCFAs and obesity in populations spanning the epidemiologic transition, and explore mechanisms by which these factors may independently and…
- Trial name
- NCT03378765
- Testing
- Diet and physical activity monitoring
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Loyola University
Healthy Volunteers
Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants
The purpose of this study is to evaluate enzyme availability in the central nervous system before and after CC-97489 administration in healthy participants
- Trial name
- NCT05065541
- Testing
- CC-97489, [18F]T-401, [11C]MK-3168
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Celgene
Atopic Dermatitis
The Effects of Polyunsaturated Fatty Acids (PUFA) on Allergic/Atopic Dermatitis
This clinical trial will study the effects of PUFA supplementation during pregnancy and lactation period on fatty acid composition in human milk and plasma of the mothers and the clinical outcome of atopic dermatitis in infants…
- Trial name
- NCT01936194
- Testing
- DHA+EPA, High Olive Oil, DHA
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Chronic Periodontitis
Omega-3 Fatty Acids in Chronic Periodontitis.
Omega 3 fatty acids is one such dietary supplement, known to modulate the host response in chronic conditions like cardiovascular diseases, rheumatoid arthritis, ischemic cerebrovascular diseases, osteoporosis by producing…
- Trial name
- omega3 (NCT01997853)
- Testing
- Omega 3 fatty acid
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Weight Reduction and Insulin Sensitivity
Fatty Acid Quality and Overweight (FO-study)
The purpose of this study is to study the health effects of fatty acid quality in healthy, overweight individuals.
- Trial name
- NCT01034436
- Testing
- fatty acid quality and overweight
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Type 2 Diabetes
Fat-induced Release of GLP-1 in Humans
This study compared the incretin-releasing effect of C8-diet oil and tributyrin with that of 20 ml olive oil on a molar basis in human volunteers.
- Trial name
- NCT02264951
- Testing
- Tributyrin, C8-diet oil, Olive oil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Healthy
The Effect of Long-Chain Polyunsaturated Fatty Acids on Cognitive Performance and Mood
The study investigates whether dietary intake of omega-3 long-chain polyunsaturated fatty acids affects learning and mood of healthy young adults.
- Trial name
- NCT00615277
- Testing
- Omega-3 fatty acids
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Healthy
Assessment of PCSO-524 Relative to a Comparator Product
A marine lipid oil extract isolated from the New Zealand Greenshell® Mussel, Perna canaliculus (P. canaliculus), contains a unique synergistic blend of marine fatty acids.
- Trial name
- NCT01564160
- Testing
- Fish Oil, PCSO-524
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Lipid Profile in Pregnancy
Maternal Dietary Lipids and Omega 3 Essential Fatty Acids Profile in Pregnant Women at Term and Their Fetuses
This study aims to investigate the omega 3 lipid profile in pregnant women at term and their fetuses compared to non pregnant women , in normal western diet adding no supplementation
- Trial name
- OM3 (NCT02925013)
- Testing
- Blood sampling, Dietary- Normal western diet
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center