Clinical trials: FeNO
Asthma Bronchiale, FeNO
Impact of Chewing Gum on FeNO Levels in Patients With Bronchial Asthma
The aim of the study is to investigate the influence of chewing gum consumption on FeNO levels in asthma patients in order to avoid systematic errors in treatment decisions.
- Conditions
- Asthma Bronchiale, FeNO, Chewing Gum
- Trial name
- NCT07053956
- Testing
- Chewing Gum
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- RWTH Aachen University
Diagnosis, Inflammation
Diagnosing Asthma With Clinically Accessible, Non-invasive, and Efficient Tests: a Child-inclusive Translational Investigation
Asthma is a common inflammatory respiratory disease affecting 11% of Canadians, but its diagnosis remains challenging, leading to delays in treatment or overtreatment.
- Conditions
- Diagnosis, Inflammation, Asthma in Children, Asthma
- Trial name
- DIVE 2 (NCT07011394)
- Testing
- FeNO, Blood eosinophil count
- Where
- 3 sites in Canada
- Volunteers
- 123 people
- Sponsor
- Université de Sherbrooke
Asthma
The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Asthma is a common inflammatory airway disease. Several researches have demonstrated a possible connection between asthma and exposure to paracetamol.
- Trial name
- NCT01073748
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Asthma
The Evaluation of FeNO for Predicting Response to ICS in Subjects With Non-specific Respiratory Symptoms
Nitric Oxide is recognized as a biological marker for many chronic airway diseases. It has been standardised for clinical use indicating airway inflammation.
- Trial name
- NSRS (NCT02294279)
- Testing
- Qvar (100 mcg)
- Where
- United Kingdom
- Volunteers
- 360 people
- Sponsor
- Research in Real-Life Ltd
Obstructive Sleep Apnea (OSA)
Fractional Exhaled Nitric Oxide as Possible Non - Invasive Biomarker to Assess Obstructive Sleep Apnea Severity
Aim of work 1. Primary aim: Asses correlation between FeNO level, OSA severity 2. Secondary aim: Clarifying FeNO's role as a biomarker to assess airway inflammation, Cut off value prediction to moderate and severe OSA and its…
- Trial name
- NCT07606898
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Asthma, Perennial Allergy
Clinical Effects of Temperature Controlled Laminar Airflow (TLA)
The purpose of this study is to determine whether clean air administered to the breathing zone with Temperature controlled Laminar Airflow (TLA) during night is effective in the treatment of perennial allergic asthma.
- Trial name
- NCT00987064
- Testing
- Temperature controlled Laminar Airflow (Protexo)
- Where
- 2 sites in Sweden
- Volunteers
- 28 people
- Sponsor
- Airsonett AB
Asthma, Asthma in Children
Diagnostic and Translational Values of Point-of-care Blood Eosinophils and Exhaled Nitric Oxide (FeNO) in People Referred by Primary Care for Suspected Asthma
Asthma is characterised by episodic symptoms (attacks) caused by airway inflammation and decreased airflow to the lungs. It affects 10% of the Canadian population and is the most common chronic disease in childhood.
- Conditions
- Asthma, Asthma in Children, Diagnosis, Inflammation
- Trial name
- DIVE (NCT05992519)
- Testing
- ¸FeNO
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Université de Sherbrooke
Small Airway Dysfunction
Extrafine ICS/LABA Versus As-Needed SABA for Small Airway Dysfunction in Symptomatic Patients With Preserved Spirometry
This study evaluates whether 4 weeks of extrafine inhaled corticosteroid/long-acting β2-agonist (beclomethasone dipropionate/formoterol fumarate, BDP/FOR) therapy improves clinical, physiological, and type 2 inflammatory outcomes…
- Trial name
- NCT07809555
- Testing
- Beclomethasone dipropionate/formoterol fumarate (extrafine), Salbutamol
- Where
- Taiwan
- Volunteers
- 93 people
- Sponsor
- Yi-Han Hsiao
Cough
The Utility of feNO in the Differential Diagnosis of Chronic Cough
In this study the investigators wish to explore the difference in 24 hr. cough counts measured using the Hull Automated Cough Counter (HACC), from baseline and after two weeks treatment with either montelukast or prednisolone in…
- Trial name
- TUF (NCT02479074)
- Testing
- Montelukast (High FeNO group), Prednisolon, Montelukast (High FeNO), Montelukast (Low FeNO group)
- Where
- United Kingdom
- Volunteers
- 49 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Asthma, Asthma in Children
Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients
This is a multi-center study to evaluate fractional exhaled nitric oxide (FeNO) measured with the Vivatmo pro in adult and pediatric subjects.
- Trial name
- NCT04450108
- Testing
- Vivatmo pro FeNO Test
- Where
- 6 sites in United States
- Volunteers
- 122 people
- Sponsor
- Bosch Healthcare Solutions GmbH
Obstructive Ventilatory Disorders
Study of Chronic Exposure of the Population Living on the Atlantic Coast and on the Caribbean Coast, in Martinique, During the Stranding Period and Outside the Stranding Period of Sargassum Seaweeds
Sargassum are pelagic brown sea algae. Two species grow on the surface of the ocean and drift freely with ocean currents in the form of slicks: the pelagic Sargassum fluitans and Sargassum natans.
- Trial name
- SÉSAR (NCT05564546)
- Testing
- FeNO (fractional exhaled nitric oxide), Spirometry, Physical examination
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Asthma
Impact of FeNO Measured With the NIOX MINO® Device in Identifying Asthma Among Patients With Prolonged Respiratory Symptoms
Overall Aim: To better understand the diagnostic process for prolonged respiratory events and determine the potential role of FeNO in assessing the possibility of asthma as the symptoms etiology.
- Trial name
- NCT01518322
- Testing
- NIOX MINO®
- Where
- 13 sites in United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Aerocrine AB
Asthma Bronchiale, Asthmatic Patients
Changes in FeNO Value During Pulmonary Rehabilitation in Patients with Asthma
This study investigates the use of fractional exhaled nitric oxide (FeNO) measurement to monitor non-pharmacological therapy during a three-week inpatient rehabilitation programme for asthma patients.
- Conditions
- Asthma Bronchiale, Asthmatic Patients, Asthmatics
- Trial name
- Asthma FeNO (NCT06751550)
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Obstructive Lung Diseases
Correlation of FeNO, Blood Eosinophils, Bronchoalveolar Lavage Findings and Bronchial Epithelium Histopathology in Patients With Chronic Obstructive Pulmonary Disease and Asthma
Scientific research focuses on "eosinophilic inflammation" as it seems to guide the therapeutic regimen in patients with asthma and COPD.
- Trial name
- NCT03845257
- Testing
- Blood sampling, FeNO, bronchoalveolar lavage, bronchoscopic tissue sampling
- Where
- 3 sites in Australia, Germany
- Volunteers
- 14 people
- Sponsor
- Heidelberg University
Asthma
Impact of a Hospital Pharmacist's Intervention on FENO (Fractional Exhaled Nitric Oxide) in Asthmatic Patients
The impact of a pharmacist's intervention on asthma control has now been well demonstrated, but its effect on inflammatory markers of FENO (Fractional exhaled nitric oxide) in asthmatic patients has been little studied in the…
- Trial name
- NCT03093363
- Testing
- Pharmacist's intervention, Questionnaires for control group
- Volunteers
- 68 people
- Sponsor
- University of Liege
Coughing
Fractional Concentration of Exhaled NO(FeNO) to Direct The Treatment of Sub-acute Cough
Cough is a common symptom that leads patients worldwide to seek medical attention. Subacute cough refers to a cough of 3-8-week duration, and is typically refractory to standard anti-tussive therapy, and a tendency to spontaneous…
- Trial name
- NCT02655562
- Testing
- Montelukast
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Use of FeNO to Identify Eosinophilic Inflammation in Patients Age 40 Years and Above With Chronic Obstructive Airways Disease
Objective: To characterize FeNO levels that may be indicative of eosinophilic airway inflammation in patients with chronic obstructive airways disease Number of participants: Approximately 200 subjects will be enrolled Reference…
- Trial name
- NCT01634620
- Testing
- NIOX MINO® Instrument (09-1100)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Aerocrine AB
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Asthma
Lignosus Rhinoceros TM02® as a Complementary Therapy for Uncontrolled Asthma
The goal of this clinical trial is to learn if TM02® works to treat partially controlled or uncontrolled asthma in adults. It will also learn about the efficacy and safety of TM02®.
- Trial name
- NCT06451328
- Testing
- Lignosus rhinoceros TM02®
- Where
- Malaysia
- Volunteers
- 17 people
- Sponsor
- University of Malaya
Asthma, Mild-to-moderate Asthma
Remission in Adults With Mild-to-moderate Asthma in Thailand
The goal of this observational study is to determine the prevalence of remission among adults with mild-to-moderate asthma, as well as the factors associated with remission in Thailand.
- Conditions
- Asthma, Mild-to-moderate Asthma, Asthma Control Level
- Trial name
- NCT07351916
- Testing
- Global Initiative for Asthma (GINA) and Asthma Control Test (ACT) questionnaires, Spirometry, Fractional exhaled nitric oxide (FeNO) test
- Where
- 2 sites in Thailand
- Volunteers
- 289 people
- Sponsor
- Thammasat University