Clinical trials: Fear
Healthy Participants
Cannabinoid Control of Fear Extinction Neural Circuits in Humans
The goal of the current proposal is to investigate the effects of a cannabinoid drug on the memory of extinguished fear in humans and the brain circuitry important for the recall of extinction learning.
- Trial name
- NCT02472847
- Testing
- Dronabinol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Trauma, Depression
Art as Healing: A Community-informed Art-based Programme (CiAbP) for Reintegrating Ex-offenders Into Society in Nigeria
The goal of this pilot experimental study is to test a community-informed art-based programme in improving community members trauma from crime and to aid the reintegration of ex-offenders into society.
- Conditions
- Trauma, Depression, Anxiety and Fear
- Trial name
- NCT05614687
- Testing
- Community-informed art-based programme, Government Media Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teesside University
Pregnancy, Climate Change Anxiety
Climate Change Education Based on the IMB Model for Pregnant Women
Climate change can affect the health of pregnant women and their babies, for example through extreme heat and air pollution. Many pregnant women worry about these effects but do not know how to protect themselves.
- Conditions
- Pregnancy, Climate Change Anxiety, Risk Perception, Fear of Childbirth
- Trial name
- NCT07871032
- Testing
- IMB-Based Climate Change Education
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Eating Disorder Symptom, Fear
Conquering Feared Foods Study
The purpose of this study is to use ecological momentary assessment (EMA) data and physiological data to asses a client's eating disorder symptoms and behaviors before and after a meal with a feared food.
- Trial name
- CFF (NCT04155788)
- Testing
- Food Exposure
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pregnancy in Adolescence, Fear
Effect of MBSR Training on Childbirth Fear, Bonding and Breastfeeding in Adolescent Pregnant Women
This randomized controlled study aims to evaluate the effect of Mindfulness-Based Stress Reduction (MBSR) training given to adolescent pregnant women and their partners on fear of childbirth, maternal and paternal bonding, and…
- Conditions
- Pregnancy in Adolescence, Fear, Mother-Child Relations, Mindfulness
- Trial name
- NCT07540923
- Testing
- Mindfulness-Based Stress Reduction (MBSR) Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Inonu University
Fear
Effect of D-cycloserine on Extinction of Fear Conditioning
This study will evaluate whether the drug D-cycloserine (DCS) can improve a type of learning called classical conditioning, in which the brain learns to associate neutral stimuli with stimuli that elicit emotional or…
- Trial name
- NCT00352586
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Musculoskeletal Pain, Musculoskeletal Pain Disorder
Dutch Version Fear-Avoidance Component Scale (FACS)
Chronic musculoskeletal disorders such as low back and neck pain are responsible for an enormous global burden. Fear-avoidance (FA) can be a predictor for the transition from subacute to chronic low back pain.
- Conditions
- Musculoskeletal Pain, Musculoskeletal Pain Disorder, Fear of Pain, Fear of Injury
- Trial name
- NCT03994861
- Testing
- Assessment of disability and behavior (by questionnaires)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Anxiety Acute, Anxiety Fear
Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
To evaluate the clinical effectiveness of a virtual reality psychological preparation app at reducing peri-operative anxiety and its associated sequelae in children aged 3-12 years old undergoing ambulatory surgery compared to…
- Conditions
- Anxiety Acute, Anxiety Fear, Peri-operative, Psychological Distress
- Trial name
- NCT03797716
- Testing
- Little Journey app
- Where
- 17 sites in United Kingdom
- Volunteers
- 596 people, healthy volunteers welcome
- Sponsor
- University College, London
Post Traumatic Stress Disorder
Fear and Avoidance in PTSD Patients
The purpose of this research study is to study how the brain learns to avoid certain stimuli or situations using an experimental paradigm.
- Trial name
- NCT04770584
- Testing
- Fear Conditioning, Avoidance conditioning, Pavlovian fear extinction learning
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anxiety and Fear, Anesthesia
Evaluating Stress Response and Anxiety Score in Paediatric Patients
To date, there have been no studies done relating serum cortisol levels and intranasal dexmedetomidine sedation. However, there was a behavioral study done on pediatric patients confirming reduction serum cortisol levels with…
- Trial name
- NCT04526652
- Testing
- Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Anxiety, Dental, Fear, Dental
Evaluation of Audio-Visual Distraction Technique on Child's Anxiety
Audio-Visual (AV) Distraction is a recent modality introduced to the entertaining market technology for adults and children. Some practitioners started using this modality of distraction in the dental practice to aid in…
- Trial name
- NCT03229720
- Testing
- Nibiru 3D Virtual Reality Headset
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgery in Children
The Effect of Informative Animated Videos Watched Before Surgery on Anxiety and Fear in Children and Their Mothers
It is important to prepare children and their mothers psychologically for surgery. There are many initiatives to achieve this psychological preparation, including interactive educational booklets for children and their families…
- Trial name
- NCT07131982
- Testing
- Informative Animated Video to be Viewed with Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Fear of Childbirth, Psychosocial Health
Effects of Solution-Oriented Approach on Psychosocial Health, Fear of Childbirth and Postnatal Senses of Security
This study was planned as a randomized controlled experimental study with posttest and control group in order to evaluate the effect of the solution focused approach method applied to primigravidas on psychosocial health, fear of…
- Conditions
- Fear of Childbirth, Psychosocial Health, Pregnancy, Postpartum
- Trial name
- NCT04820296
- Testing
- Solution-Oriented Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Obsessive Compulsive Disorder
Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
The purpose of this study is to find out more about how the brain stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human beings learn not to fear.
- Trial name
- NCT02467374
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Inhalation Therapy; Complications
The Effect of Watching Informative Animation on Fear and Anxiety in Children
The aim of this project was to determine the effect of showing informative animations to children on anxiety and fear during inhalation therapy. This project is a randomized controlled trial.
- Trial name
- NCT05861232
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mukader Kaya
Dental Fear
The Effect of Parental Presence on Dental Fear
150 children aged between five and seven years presenting for the first dental visit, whose parents consented to participate in the study were selected from patients reporting to the dental clinics Riyadh Colleges of Dentistry…
- Trial name
- NCT02619981
- Testing
- Restorative procedure, Maxillary infiltration anesthesia with 2%Lidocaine
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Health Care Utilization
Evaluation of Emails Promoting Mail-order Pharmacy
In this evaluation, four versions of emails will be sent to eligible health plan members who are not currently enrolled in the health system's mail-order pharmacy. A control group will not receive any communication.
- Trial name
- NCT04587063
- Testing
- Fear Appeals, Message about Future Healthcare Costs, Endorsement from a Doctor
- Where
- United States
- Volunteers
- 5,266 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Panic Disorder
Changes of Cerebral Glucose Metabolism and After 12 Weeks of Escitalpram Treatment in Panic Disorder
Panic disorder is one of the most prevalent psychiatric disorders and recently abnormal fear network is known to be implicated in the pathophysiology of panic disorder.
- Trial name
- NCT00767871
- Testing
- Lexapro
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Neural Dynamics of the Acquisition and Retention of Fear Learning and Active Avoidance Learning
Use Electroencephalogram to Study Neural Dynamics of Fear Conditioning and Avoidance Learning Circuit in Humans
The purpose of this study is to examine which event-related potentials (ERPs) and event-related oscillations (EROs) are associated with fear conditioning, avoidance learning, and memory recall for fear and avoidance, where are…
- Trial name
- NCT06240052
- Testing
- Conditioning and active avoidance paradigm (CAAP)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer, Kinesiophobia
Breast Cancer and Kinesiophobia and Physical Activity
Breast cancer is the most common type of cancer in women worldwide. A significant number of breast cancer survivors develop many complications.
- Trial name
- NCT05090098
- Testing
- None intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University