Clinical trials: Fear of Spiders
Specific Phobia, Arachnophobia
Use of Safety Behaviors in Exposure Therapy for Arachnophobia
This study examines the impact of safety behaviors (i.e., unnecessary protective actions) on outcomes of exposure therapy for spider phobia.
- Conditions
- Specific Phobia, Arachnophobia, Spider Phobia
- Trial name
- NCT04470882
- Testing
- Exposure with faded safety behaviors, Exposure without safety behaviors, Exposure with unfaded safety behaviors
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Nevada, Reno
Specific Phobia
The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia
Exposure-based cognitive-behavioral therapy (i.e., "exposure therapy"), which entails repeated and prolonged confrontation with feared situations/stimuli, is the most effective treatment for anxiety disorders (e.g.…
- Trial name
- NCT03233113
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Specific Phobia, Cognitive-behavioral Therapy
Virtual Reality Exposure in Spider Phobia
While knowledge on the neurobiological signatures of fear and anxiety disorders and, in particular, their association with treatment outcome is accumulating, clinical translation still awaits empirical proof of evidence.
- Conditions
- Specific Phobia, Cognitive-behavioral Therapy, Virtual Reality
- Trial name
- NCT03208400
- Testing
- virtual reality exposure
- Where
- 2 sites in Germany
- Volunteers
- 338 people
- Sponsor
- Julius-Maximilians University
Phobic Disorders
The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants
This study evaluates the role of treatment success expectation in spider fearful individuals on the actual treatment success. Half of participants will have positive treatment success expectations, while the other half will have…
- Trial name
- NCT03012035
- Testing
- positive treatment expectations, neutral treatment expectations
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Fear of Spiders, Acute Stress Reaction
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
This clinical trial aims to evaluate the nature and duration of effects of three FDA-approved medications (propranolol and hydrocortisone) on military-relevant cognitive, emotional, and motor performance following an exposure to…
- Trial name
- NCT06982183
- Testing
- Propranolol, Hydrocortisone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Specific Phobia
Spider Phobia Opposite Action Treatment Study
This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment.
- Trial name
- NCT02905279
- Testing
- Biofeedback Relaxation Training, Exposure Therapy, Exposure with Threat-Relevant Opposite Actions
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobia
Extinction Generalization in Exposure Therapy
Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider…
- Trial name
- NCT03031002
- Testing
- Exposure treatment for spider fear
- Volunteers
- 77 people
- Sponsor
- Ruhr University of Bochum
Phobias Snakes, Phobias Spiders
Bringing Exposure Therapy to Real-Life Context With Augmented Reality
In this patented project, U.S. Patent No. 10,839,707, the investigators will develop an augmented reality exposure therapy method for arachnophobia, and fear of snakes, to test in the clinic.
- Trial name
- ARET (NCT03649347)
- Testing
- Augmented reality exposure therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wayne State University
Phobic Disorders
Neurophysiological Correlates of Exposition Therapy in Spider Phobia
This study aims to investigate the neurophysiological correlates of spider phobia and its treatment with CBT based Exposure Therapy.
- Trial name
- NCT03653923
- Testing
- Exposure Therapy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Specific Phobia
Effects of Stress on Exposure Therapy
This study investigates whether stress can augment exposure therapy outcome in patients with specific phobia (spider phobia).
- Trial name
- NCT03505437
- Testing
- Cold water condition, Warm water condition
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Ruhr University of Bochum
Spider Phobia
Gamification in the Treatment of Spider Phobia
Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with…
- Trial name
- NCT04423783
- Testing
- 7-day exposure therapy via self-developed app according to (Haberkamp et al., submitted), Therapist-guided one-session online exposure therapy according to (Öst, 1989)
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Anke Haberkamp
Spider Phobia
EMDR in Spider Phobia: Work Mechanisms and Treatment Outcome
The goal of this study is to increase the efficiency of exposure in virtual reality (VR). Based on the EMDR research the investigators would like to show that the implementation of eye movements during the VR exposure results in…
- Trial name
- NCT02973919
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Virtual Reality Exposure Therapy
- Volunteers
- 53 people
- Sponsor
- University of Regensburg
Arachnophobia, Cynophobia
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs.
- Conditions
- Arachnophobia, Cynophobia, Ophidiophobia
- Trial name
- NCT06302868
- Testing
- Telemedicine Exposure Therapy Using Photos and Videos, Telemedicine-Based Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of South Florida
Specific Phobias
tDCS-Augmented Exposure Therapy for Pathological Fear
This double-blind randomized controlled clinical trial aims to test whether transcranial direct current stimulation (tDCS) can be used to modulate fear extinction learning during exposure therapy for pathological fear, including…
- Trial name
- NCT03095482
- Testing
- Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anxiety Disorders, Arachnophobia
Optimizing Exposure Therapy With Mental Rehearsal
Treatment response rates for cognitive behavioral therapy (CBT) across anxiety disorders average approximately 50% post-treatment (Loerinc et al, 2015), evidencing significant 'return of fear', the re-emergence of a partially or…
- Trial name
- NCT03934385
- Testing
- Mental Rehearsal, Exposure
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Los Angeles
Phobia, Specific
Virtual Reality Immersive Method for Spider (Phobia) Exposure Therapy (VIMSE)
The aim of this study is to examine the efficacy of virtual reality exposure therapy as a treatment for specific phobia (spiders).
- Trial name
- VIMSE (NCT02533310)
- Testing
- OST treatment with in-vivo spiders, VR-OST treatment with virtual spiders
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Stockholm University
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University