Clinical trials: Feasibility Pilot Study
Gynecologic Cancer, Anemia, Iron Deficiency
Ferric Derisomaltose/Iron Isomaltoside and Outcomes in the Recovery of Gynecologic Oncology ERAS
Iron deficiency has been reported in up to 35% of patients with a gynecologic malignancy. These patients often require surgical intervention to determine the stage and to treat their illness.
- Conditions
- Gynecologic Cancer, Anemia, Iron Deficiency, Surgery
- Trial name
- FORGE (NCT05467319)
- Testing
- Ferric Derisomaltose Injection, Normal saline
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Minor Procedural Pain
Lazanda Fentanyl Nasal Spray Pre Radiofrequency Nerve Ablations(RFA) of Lumbar Facet Joints
The purpose of this study is to evaluate the effectiveness, feasibility and safety of intranasal fentanyl (Lazanda) as an alternative to the current gold standard (diazepam) to produce anxiolysis and improve patient comfort…
- Trial name
- RFA (NCT02571634)
- Testing
- Lazanda
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Feasibility Studies, Physical Activity and Wellbeing
Physical Activity Intervention for Older Family Carers
The goal of this pilot trial is to learn whether a six-month physical activity program tailored for older family caregivers can be successfully delivered and whether participants are willing and able to take part in it.
- Trial name
- CAREFIT (NCT07653061)
- Testing
- Physical activity intervention for older family caregivers, Health education
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University
Relationship, Family, Well-Being, Psychological
REducing pSychological diSTress To Optimize Recovery of Elderly ICU Survivors and Caregivers (RESTORE-ICU)
This research study aims to explore whether a set of simple breathing techniques and guided meditations can improve the psychological well-being and recovery of ICU survivors and their caregivers.
- Trial name
- RESTORE-ICU (NCT06867367)
- Testing
- Isha Kriya and Naddi Shuddhi
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke, Complication
A Pilot Study on the Feasibility Study of a Novel Virtual Reality (VR)-Based Post-stroke Hemineglect Evaluation System
The normal value of the new virtual reality (VR)-based hemineglect evaluation system is obtained and its validity is checked by whether there is a difference in the evaluation results between normal people, stroke patients with…
- Trial name
- NCT05145699
- Testing
- VR-based post-stroke hemineglect evaluation system
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Emotion Regulation
Emotion Regulation For All (ER4ALL) Study
In the present study, the investigators aim to examine the feasibility of a classroom-based emotion regulation skills training within a tertiary curriculum.
- Trial name
- MASHUP1 (NCT05746234)
- Testing
- Emotion Regulation Course
- Where
- Cyprus
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Autosomal Dominant Polycystic Kidney Disease, Kidney Disease
New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease
The purpose of this study is to establish normal Magnetic Resonance quantitative values (tissues stiffness, Apparent Diffusion Coefficient values and Blood Oxygen Level Determination values for both renal cortex and medullary…
- Trial name
- MRI Pilot (NCT02250287)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiovascular Risk Factors, Autoimmune Diseases
Universal Capillary Screening for Chronic Autoimmune, Metabolic and Cardiovascular Diseases: Feasibility and Acceptability Pilot Study.
This study represents a model for a public health program based on a general population screening for the most prevalent chronic metabolic, cardiovascular and autoimmune diseases across adulthood, childhood and adolescence.
- Trial name
- UNISCREEN (NCT05841719)
- Testing
- Screening test
- Where
- Italy
- Volunteers
- 1,535 people, healthy volunteers welcome
- Sponsor
- Emanuele Bosi
Preterm Birth
The GROWNDUP Study of Late Preterm Births
This pilot study will examine the feasibility of conducting a large randomized clinical trial (RCT) to examine the role of a novel, specialized follow-up clinic in preventing complications among late preterm infants (LPTB), born…
- Trial name
- GROWNDUP (NCT01747603)
- Testing
- Specialized LPTB clinic
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Perinatal Depression
Preventing Perinatal Depression
The goal of this pilot study is to evaluate the acceptability, feasibility, mechanisms of action, and efficacy of Center M. Center M is a group-based, mindfulness-based Cognitive Behavioral Therapy (CBT) intervention to treat…
- Trial name
- NCT06525922
- Testing
- Center M
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Fall Prevention, Physical Activity
Pilot of a Group-based Program on Lifestyle-integrated Functional Exercise (LiFE) in Older Persons
This feasibility pilot is part of the project "LiFE-is-LiFE" (2017-2020). It is based on the Lifestyle-Integrated Functional Exercise (LiFE) program by Clemson et al., which has proven effective in improving strength, balance…
- Trial name
- NCT03412123
- Testing
- group lifestyle-integrated functional exercise
- Where
- Germany
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Cognition, Multiomics
Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy Adults
This study is a pre-post, open-label cohort study designed to investigate how a food-grade probiotic supplement affects biological measurements and wellbeing in healthy adults.
- Conditions
- Cognition, Multiomics, Microbiome Analysis, Metabolome
- Trial name
- PROFILE (NCT07457242)
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- OneCarbon
Depression/Anxiety
Acceptability and Feasibility of an In-person 8-week Mindfulness-Based Cognitive Therapy Program Among Undergraduates
Mental health among university students has emerged as a significant global issue. Recent meta-analyses reveal that 25% of students experience depressive symptoms and 14% exhibit suicidal behaviors.
- Trial name
- MFS (NCT06757842)
- Testing
- Mindfulness in Students
- Where
- Chile
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Obesity Prevention, Healthy Lifestyle Behaviors
Feasibility of a Healthy Lifestyle Program (Athletes for Life) in Mexicali, Baja California
Childhood obesity affects 36.6% of children in Mexico and nearly 50% in Baja California. Traditional weight-centered interventions yield modest and unsustainable results.
- Trial name
- NCT07847645
- Testing
- Healthy lifestyle program, Control group
- Where
- Mexico
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Recurrent Severe Aplastic Anemia, Refractory Severe Aplastic Anemia
A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia
This phase I trial evaluates the safety and feasibility of using a reduced-intensity regimen of cyclophosphamide, pentostatin, and anti-thymocyte globulin prior to a CD4+ T-cell depleted haploidentical hematopoietic cell…
- Trial name
- NCT05757310
- Testing
- Anti-Thymocyte Globulin, Biospecimen Collection, Bone Marrow Aspirate
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Depression, Anxiety Disorders
Pilot Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19
This is a pilot feasibility study of remotely delivered Problem Management Plus, a low-intensity psychological intervention, delivered in five sessions to adults affected by crisis.
- Conditions
- Depression, Anxiety Disorders, Psychological Distress
- Trial name
- PM+ (NCT04617262)
- Testing
- Remote Problem Management Plus
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The New School
Post Operative Pain, Spinal Surgery
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to End Narcotic Dependence, MEND trial) to assess the feasibility and…
- Trial name
- MEND (NCT07222072)
- Testing
- Methadone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Caregiver, Malignant Neoplasm
Comic Art Creation as Supportive Care in Cancer Patients and Caregivers
This pilot clinical trial studies how well comic art creation works as supportive care in cancer patients and caregivers. Participating in a comic art creation workshop may help patients and their family members or friends share…
- Trial name
- NCT03067766
- Testing
- Art Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Obesity, Physical Activity
Tu Salud Si Cuenta Worksite: Pilot Intervention Study
Building on existing intervention strategies of the Tu Salud Si Cuenta media campaign, this proposed worksite pilot study will be testing a new feature by designing worksite promotion intervention strategies.
- Conditions
- Obesity, Physical Activity, Diet, Stress
- Trial name
- TSSC Worksite (NCT00870207)
- Testing
- Tu Salud Si Cuenta Worksite Intervention
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Muscle Architecture, Ultrasonic Diagnosis
Feasibility and Preliminary Effects of a Structured Resistance Training Program in Children Aged 10-14 Years
This study is a randomised controlled pilot trial designed to evaluate the feasibility, safety, and preliminary efficacy of a 12-week resistance training intervention in children aged 10-14 years.
- Trial name
- NCT07512570
- Testing
- Progressive Resistance Training Program
- Where
- Czechia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic