Clinical trials: Feasibility Pilot Study
Healthy Adults
Feasibility, Acceptability, and Safety of a Drug-Free Nasal Spray in Frontline Healthcare Workers
This study looked at whether frontline healthcare workers could use a drug-free nasal spray twice a day for 8 weeks, whether it was safe, and whether they found it acceptable.
- Trial name
- NCT07887958
- Testing
- Nasal Spray
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Akita Biosciences, Inc.
Diabetes Mellitus, Type 2 Diabetes
The Diabetes Staging System in Patient Aligned Care Teams
The purpose of this study is to examine the feasibility/acceptability of the Diabetes Staging System (DSS) in Patient Aligned Care Teams (PACT) teams and its ability to increase sodium-glucose cotransporter-2 inhibitor (SGLT2i)…
- Trial name
- NCT06142006
- Testing
- Diabetes Staging System (DSS) use among Primary Care Teams
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Durham VA Medical Center
Work-Related Condition, Work-Related Stress Disorder
Congitive Behavioral Therapy Workshop for Content Moderators
Professional content moderators play a critical role in preventing Internet users from being exposed to more sensitive content. However, recent literature has shown that this work places content moderators at increased risk for…
- Trial name
- NCT06383715
- Testing
- Cognitive-Behavioral Therapy Workshop for Content Moderators
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Valencia
Well Being
Group Laughie Intervention for Well-Being in Earthquake Survivors: A Pilot Study
Mental health and quality of life may be negatively impacted among earthquake survivors. This pilot study aims to evaluate the feasibility, acceptability, and potential effects of a 1-minute Laughie (Laugh Intentionally Everyday)…
- Trial name
- NCT07563140
- Testing
- Laughie
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Dietary Behaviours, Sustainable Healthy Diet
Behaviour-focused Personalised Nutrition Intervention
The aim of this study is to test the efficacy, feasibility, and acceptability of a novel, behaviour-focused personalised nutrition intervention compared to a control personalised nutrition intervention for improving adherence to…
- Conditions
- Dietary Behaviours, Sustainable Healthy Diet, Personalised Nutrition
- Trial name
- NCT06631469
- Testing
- Personalised behavioural sustainable and healthy dietary recommendations, Personalised sustainable and healthy dietary recommendations
- Where
- Ireland
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Fear of Falling
Feasibility of Aktiv Gegen Sturzangst (AGES) in Assisted Living Facilities
Aktiv Gegen Sturzangst (AGES) is a multicomponent group intervention combining cognitive behavioral therapy and structured exercise to address fear of falling in older adults receiving services from assisted living facilities.
- Trial name
- AGES (NCT07787819)
- Testing
- Multicomponent fear of falling intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Eric Lenouvel
Stress
Nurse Health Pilot: Feasibility and Acceptability of a Virtual ACT-intervention in Nurses During COVID-19
Frontline nurses increasingly face challenges between executing their jobs to the best of their ability and caring for their own physical and mental health.
- Trial name
- NHP (NCT04821037)
- Testing
- ACT
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Andrew Gloster
Breast Engorgement, Lactation Disorders
Lymphatic Drainage Versus Ultrasound for Postpartum Breast Engorgement: A Pilot Study
In this article, women were randomly assigned to the manual lymphatic drainage group, therapeutic ultrasound group, and control group, and the breast pain, swelling hardness, and milk excretion before and after each treatment…
- Trial name
- NCT06129344
- Testing
- Manual Lymphatic Drainage Group, Ultrasound therapy group
- Where
- Taiwan
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Eating Disorders in Children
Feasibility and Acceptability of the BE REAL Let's Eat Curriculum in Middle Schoolers
The purpose of this study is to evaluate the feasibility and acceptability of 'Let's Eat' and its capacity to change eating behavior and body appearance/functionality considerations in adolescents aged 11-14 years.
- Trial name
- NCT07615088
- Testing
- Let's Eat Nutrition Curriculum
- Where
- 2 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Charlotte
Domestic Violence, Child Maltreatment
RISE With Residents
Prevention of child maltreatment (CM) remains a public health priority in Canada; approximately one-third of Canadians report exposure to at least one form of CM.
- Conditions
- Domestic Violence, Child Maltreatment, Pediatric ALL, Psychiatry
- Trial name
- RISE Residents (NCT05490121)
- Testing
- Violence, Evidence, Guidance, Action Project (VEGA) Education Intervention
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- McMaster University
Feasibility Studies, Physical Activity and Wellbeing
Physical Activity Intervention for Older Family Carers
The goal of this pilot trial is to learn whether a six-month physical activity program tailored for older family caregivers can be successfully delivered and whether participants are willing and able to take part in it.
- Trial name
- CAREFIT (NCT07653061)
- Testing
- Physical activity intervention for older family caregivers, Health education
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University
Hyperthermia
Sauna Detoxification Study: Pilot Feasibility
The goal of this study is to assess the feasibility of the approach, conduct a dose-finding investigation, and obtain pilot data on hyperthermia via sauna to apply in follow-up trials in the assessment of human chemical body…
- Trial name
- NCT01576822
- Testing
- This protocol will utilize a sauna as the primary method of detoxification.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Insulin Resistance, Type 2 Diabetes
Alpelisib Challenge Test (ACT)
The goal of this study is to test a potentially easier method for measuring how much insulin a person is capable of producing than the current gold-standard method, the "hyperglycemic clamp." Participants will come in for a…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
- Trial name
- NCT07778524
- Testing
- Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Overweight and Obesity
Evaluating the Feasibility of a Dietary Weight Loss Program to Overcome Obesity and Its Comorbidity Among Arab Populations
This study aims to develop and test a culturally tailored online weight loss program for the Saudi population. Building upon the success of a previous program in the United States, the research team will adapt educational…
- Trial name
- NCT06415695
- Testing
- Education sessions
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asma Yahya
Underweight, Malnutrition
Study of Effect of Microfinance on Under 5 Health in Rural India
Investigators propose a feasibility and pilot study for a cluster randomised controlled trial. The proposed trial will evaluate the effects of an economic intervention (microfinance) in self-help groups of poor and marginalised…
- Trial name
- NCT01845545
- Testing
- Early provision of microfinance
- Where
- India
- Volunteers
- 2,469 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Neuro-Degenerative Disease, Cancer
Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies
This will be a Phase 1, open label study of the pharmacokinetics (PK) and pharmacodynamics (PD) of clonidine, an alpha-2 adrenergic (a2a) agonist, in healthy volunteers.
- Trial name
- a2a Agonist (NCT04030572)
- Testing
- Clonidine Pill
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Physical Inactivity
The Role of Intermediaries in Connecting Individuals to Local Physical Activity - Study Protocol
Intermediaries help people to connect to community-based services and supports, including physical activity and exercise groups (physical activities). They do this by acting as a link person.
- Trial name
- NCT06260995
- Testing
- Social Prescribing Link Worker Intermediary Intervention, Local Sports Partnership Community Development Officer Intervention
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Snoring
Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring
This research study proposes to determine how well tolerated and effective lower and upper oral dental devices are at reducing snoring.
- Trial name
- NCT04900285
- Testing
- Delta Dental Oral Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norton Healthcare
Fatigue, Anxiety
Fatigue, Anxiety, Music, and Entertainment (FAME) Study
Evaluate the feasibility of a six-week group drumming intervention on fatigue, anxiety, and cognitive impairment when compared to an attentional control for cancer patients who have undergone at least one treatment session of…
- Trial name
- FAME (NCT03955003)
- Testing
- Group Drumming, Attention Control
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Utah