Clinical trials: Feasibility Studies
Urea Cycle Disorders
Study to Evaluate 13 C Isotope Ratio Measurement for Urea Cycle Capacity Assessment
In this short-term study a method for the evaluation of the metabolic competency of the urea cycle in vivo will be assessed. In order to monitor the efficacy of new treatment options for patients with urea cycle disorders and to…
- Trial name
- NCT01002469
- Testing
- sodium [1-13C] acetate
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cytonet GmbH & Co. KG
Examination Phobia
Dogs Offering Guidance: Therapeutic Observation for Reducing Examination Anxiety (DOGTOR).
Physiotherapists work closely with patients to assess, diagnose and treat a variety of conditions. Thus, it is essential that education should assess these key competencies through both written examinations (to measure cognitive…
- Trial name
- NCT07817459
- Testing
- Canine Group
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- La Trobe University
Postoperative Hemorrhage, Postoperative Anemia
Autologous Whole Blood Management for Transfusion Reduction in Adult Cardiac Surgery Patients
The goal of this pilot trial is to test a protocol for a planned Canada-wide clinical trial looking at whether or not the use of a patients own blood works as good as the current standard of care using donated blood products to…
- Conditions
- Postoperative Hemorrhage, Postoperative Anemia, Postoperative Blood Loss
- Trial name
- NCT05889494
- Testing
- Autologous Whole Blood Management, Standard Care involving allogenic and/or derivative transfusion.
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Tuberculosis
A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi
Despite tremendous efforts, an effective tuberculosis (TB) vaccine remains elusive. TB continues to infect and kill many. In 2021, TB infected more than 10 million and killed 1.6 million people.
- Trial name
- MLWBCGCHIM (NCT06178666)
- Testing
- BCG
- Where
- Malawi
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Allergy and Immunology
An Investigator-initiated, Explorative Trial Evaluating the Effect of SAT-008 in Healthy Adults
The purpose of this exploratory study is to evaluate the efficacy, safety, and feasibility of a novel digital device called SAT-008 in healthy adults.
- Trial name
- SAT-008 (NCT04916145)
- Testing
- SAT-008
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
HIV-1-infection, Hepatitis C, Chronic
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy
The study hypothesis is to determine the feasibility of switching HIV-HCV co-infected patients receiving methadone or buprenorphine/naloxone as opioid substitution therapy with suppressed HIV RNA viral load on current…
- Conditions
- HIV-1-infection, Hepatitis C, Chronic, Methadone Dependence, Opioid Dependence
- Trial name
- NCT03549312
- Testing
- Genvoya, Epclusa, Biktarvy
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Procedural Pain, Pain Catastrophizing
Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy
This study is being done to see if nitrous oxide during vasectomy decreases pain and anxiety, and also assess whether patients have better satisfaction when they control their own level of nitrous oxide during the procedure.
- Conditions
- Procedural Pain, Pain Catastrophizing, Procedural Anxiety
- Trial name
- SANO-VAS (NCT05895383)
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Safety Issues, Feasibility
A Pilot Study of Deep Cervical Lymphatic-venous Anastomosis in the Treatment of Alzheimer's Disease
Alzheimer's disease (AD) is the most prevalent form of dementia, affecting 3-4% of the population over a lifetime. It's characterized by abnormal Amyloid-beta (Aβ) and tau protein expression and accumulation in the central…
- Conditions
- Safety Issues, Feasibility, Therapeutic Value
- Trial name
- NCT06448442
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Asthma Self Management
Use of Mobile Phone Application for Asthma Sele Management
This study aimed to assess the feasibility and acceptability of self-management provided through a mobile application.
- Trial name
- NCT06900361
- Where
- Malawi
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Kamuzu University of Health Sciences
Newborn Morbidity
Reducing Adverse Delivery Outcomes Through Teleneonatology: A Feasibility Study
Teleneonatology, the use of audio-video communication to facilitate neonatal-perinatal care, may bridge the resuscitation quality gap by connecting centers with lower level care to experienced care providers.
- Trial name
- NCT04258722
- Testing
- Resuscitation Personnel
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Smoking Cessation
The Staff Stop Smoking Project
Participants will be randomised to either standard care or to receive our help to quit programme. The study will only be available to Portsmouth Hospital Trust staff member.
- Trial name
- STOP (NCT04263545)
- Testing
- Group session with smoking cessation counsellor, Standard Care
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Asthma
A Pilot and Feasibility Study of Mobile-Based Asthma Action Plans
Investigators from University of Arkansas for Medical Sciences Department of Pediatrics and University of Arkansas for Medical Sciences Center for Distance Health will collaborate to develop a mobile-based Asthma Action Plan…
- Trial name
- NCT01514760
- Testing
- Mobile-based Asthma Action Plan
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Healthy, College Students
Testing the Feasibility and Impact of a Whole-Food Plant-Based Diet Intervention on College Students
The goal of this pilot randomized controlled trial (RCT) was to assess the feasibility, acceptability, and impacts of a whole-food plant-based (WFPB) vegan diet intervention for undergraduate university students randomly…
- Conditions
- Healthy, College Students, Diet Interventions, Vegan Diet
- Trial name
- NCT07903935
- Testing
- Interactive intervention group, Lecture-based intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Lung Cancer
Hatha Yoga in Lung Cancer Couples
The goal of this research study is to learn the opinion of patients and their caregiving about a couple-based Hatha Yoga program during treatment for cancer.
- Trial name
- NCT01952860
- Testing
- Hatha Yoga, Questionnaires
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Moral Injury
Assessing the Implementation and Feasibility of the SMART-MR
The objective of the proposed pilot study is to assess the feasibility and implementation of the SMART-MR program, an integration of stress management, general resilience, and moral resilience skills, with frontline staff who…
- Trial name
- NCT05122910
- Testing
- Stress Management and Resilience Training - Moral Resilience (SMART-MR) program
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Fertility, Fertility, Male
Plan A Occlusion and Reversal System Feasibility Study
Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then…
- Conditions
- Fertility, Fertility, Male, Healthy Male Adults
- Trial name
- NCT07361120
- Testing
- Occlusion System
- Where
- 3 sites in Australia, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Preoperative Anxiety
Feasibility Study Evaluating the Silva Module During the Anaesthesiology Consultation Before an Elective Surgery
In this feasibility study, feasibility, acceptability and an initial clinical efficacy of the new module of Hypnosis and Virtual Reality (or Digital Sedation), Silva, will be evaluated.
- Trial name
- Silva (NCT04379882)
- Testing
- Digital Sedation (Silva)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oncomfort
Pancreatic Cancer, Pancreatic Neoplasms
Pancreatic Cancer Screening Using the Enzeavour Assay in Japan
This nationwide, multicenter, prospective, single-arm interventional feasibility study evaluates the Enzeavour Pancreatic Cancer assay in routine health checkups and cancer screening in Japan.
- Trial name
- ENZEAVOUR FS (NCT07605819)
- Testing
- Enzeavour Pancreatic Cancer Assay
- Where
- 69 sites in Japan
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Cosomil, Inc.
HIV
Acceptability/Feasibility of HIV Testing by ELISA or Rapid Test to Adult Patients in Paris, France
CDC recommends universal HIV testing in all adults, at least once during life, to reduce the pool of infected patients unaware of their status.
- Trial name
- NCT02574208
- Testing
- HIV testing by ELISA, HIV testing by rapid test
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Hopital Lariboisière
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