Clinical trials: Feasibility Study
Malaria
Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan
This study aims to explore whether SMC is an effective intervention in the context of Northen Bahr el Gazal state, South Sudan. It also aims to assess the protective efficacy of the antimalarials used in SMC in the target…
- Trial name
- NCT05471544
- Testing
- Sulfadoxine pyrimethamine, Amodiaquine
- Where
- South Sudan
- Volunteers
- 3,575 people, healthy volunteers welcome
- Sponsor
- Malaria Consortium
Gastrointestinal Cancer
Endoscopic Nebulizing Device for Surgical Haemostatic-sealant Glubran® 2 Usability Trial in EMR and ESD
The aim of this single-center study is to evaluate the feasibility of the technique, usability and safety of the device ENDONEB.
- Trial name
- NCT06588881
- Testing
- nebulized application of the haemostatic surgical sealant after gastrointestinal endoscopic resection
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GEM SRL
Pregnancy
Partnership to Improve Nutrition and Adiposity in Prenatal Clinical Care: a Pilot and Feasibility Study
This study will pilot and assess feasibility of a prenatal intervention for obese pregnant women based on the Diabetes Prevention Program (DPP).
- Trial name
- NCT02520167
- Testing
- Dietary and Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Lung Carcinoma
Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial
This phase II trial evaluates how a virtually supervised exercise intervention in combination with group counseling affects inflammation and the bacterial composition (microbiome) of the gut in smokers who are at high risk for…
- Trial name
- NCT06445192
- Testing
- Best Practice, Biospecimen Collection, Exercise Counseling
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Skin Laxity
Feasibility Study: Treatment of Post-surgery and Surgery Naive Patients Who Failed to Respond to a Previous Ulthera Treatment
Up to 10 subjects will be enrolled. All subjects will receive an increased density UltherapyTM treatment at dual depth. Treatments will be provided to the lower 2/3 of the face and neck.
- Trial name
- NCT01708252
- Testing
- Ulthera System Treatment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Amblyopia
Children's Eye Examination and Testing At Home Study
Repeated measures observational study of tablet-based children's visual acuity tests.
- Trial name
- CHEETAH (NCT06980415)
- Testing
- Kay Pictures iSight
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Severe Mental Disorder, Diabetes Mellitus
Electronic Clinical Decision Support for Diabetes and Dysglycaemia in Secondary Mental Healthcare
People with serious mental illness (SMI) such as schizophrenia, schizoaffective disorder and bipolar affective disorder have a significantly reduced life expectancy, caused in part by increased incidences of mortality from…
- Conditions
- Severe Mental Disorder, Diabetes Mellitus, Dysglycemia, Staff Attitude
- Trial name
- NCT04792268
- Testing
- Access to eCDSS on wards
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- King's College London
Risk Behavior, Cognitive Decline
Multidomain Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention
The overarching aim is to develop and deploy a multidomain intervention delivered on a mobile application to help middle-aged to older adults reduce their risk for dementia by improving a set of modifiable lifestyle risk factors…
- Trial name
- NCT05141578
- Testing
- Luci Coach Assisted Intervention
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- LuciLab
Sexually Transmitted Diseases, HIV
Recruiting African American Fathers/ Sons
The purpose of this study is to develop and pilot test recruitment methods for a future study of prevention of sexually transmitted infections (STI), including the human immunodeficiency virus (HIV), among Black adolescent boys…
- Trial name
- NCT02811848
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Duke University
Insulin Resistance, Hyperinsulinemia
Effect of Alpelisib in Healthy Volunteers
The goal of this clinical trial is to test a single dose of the phosphoinositide-3-kinase (PI3K) inhibitor alpelisib versus placebo in healthy volunteers.
- Conditions
- Insulin Resistance, Hyperinsulinemia, Dyslipidemias
- Trial name
- NCT05733455
- Testing
- Alpelisib 150 mg [Piqray], 2 overencapsulated tablets (total: 300 mg), FreeStyle Libre Pro, Oral glucose tolerance test (OGTT) with Trutol glucose beverage
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Pain
Understanding Persistent Pain Using a Decision Aid Tool in a Scottish Pharmacy Setting.
Persistent pain describes long term pain that is present nearly every day. It is common and affects millions of people in the United Kingdom.
- Trial name
- UPP (NCT05102578)
- Testing
- Digital Decision Aid Tool
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Telemedicine
The Feasibility Study for Real-time Remote CT Reading for Suspected Acute Appendicitis Using iPhone
1. Purpose The investigators aim to evaluate the feasibility of iPhone based remote control system as a real-time remote CT reading tool for suspected appendicitis under 3G network and the suboptimal illumination. 2.
- Trial name
- Telemedicine (NCT02108717)
- Testing
- Remote CT reading using the iPhone, CT reading using LCD monitor
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Coeliac Disease
Case Finding for Coeliac Disease Using a Point of Care Test in a Pharmacy Setting
This study aims to assess whether it is feasible to use a point of care test to increase the detection of coeliac disease in a pharmacy setting.
- Trial name
- NCT02675283
- Testing
- Simtomax
- Where
- United Kingdom
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Pre-Eclampsia
Precision Medicine for Prediction & Prevention of Early Pre-eclampsia
This study aims to evaluate the feasibility of implementing a clinical model for precision screening of early pre-eclampsia into the current prenatal screening service at Sunnybrook Health Sciences Center (SHSC).
- Trial name
- NCT04412681
- Testing
- Enhanced PE Screening
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pregnancy Related, Sleep
Sleep in Late Pregnancy - Artificial Intelligence Development for the Detection of Disturbances and Disorders
SLeeP AID4 is a single-group, single-arm, Canada-wide, non-randomised, unblinded, in-home, observational study to prospectively collect and build a data set of natural sleep behaviour and physiology in maternal-fetal dyads (and…
- Conditions
- Pregnancy Related, Sleep, Sleep-Disordered Breathing, Sleep Disturbance
- Trial name
- SLeeP AID4 (NCT05376475)
- Testing
- Infrared video-audio camera, Level III home sleep apnea test, Maternal-fetal transabdominal electrocardiographic heart rate monitor
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Onychomycosis of Toenail
Light Therapy for Onychomycosis Study
This is a pilot prospective study designed to capture information about the safety and effectiveness of the ToeFX Therapy Light.
- Trial name
- NCT05139888
- Testing
- Single wavelength light (red) only, Dual wavelength light (red/blue)
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- ToeFX Inc.
Vital Signs
Vital Signs Patch Early Feasibility and Usability Study v1.0
To assess the feasibility and usability of the Vital Signs Patch (VSP) System in the in-patient hospital setting to monitor vital signs using a patch, brain, gateway, and console.
- Trial name
- VSP (NCT02524470)
- Testing
- VSP System - NEHB Configuration, VSP System - PAL Configuration
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- LifeWatch Services, Inc.
Opaque Bottles, Conventional, Clear Bottles
Opaque Bottle Study
The proposed research aimed to conduct an intervention study assessing the effect of feeding mode (clear versus opaque bottle) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03711370
- Testing
- Clear Bottle, Opaque Bottle
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Tuberculosis
A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi
Despite tremendous efforts, an effective tuberculosis (TB) vaccine remains elusive. TB continues to infect and kill many. In 2021, TB infected more than 10 million and killed 1.6 million people.
- Trial name
- MLWBCGCHIM (NCT06178666)
- Testing
- BCG
- Where
- Malawi
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Testing, Reality
The Impact of ResuGlove as a Chest Compression Feedback Device
The goal of this simulation-based randomized trial is to assess if the newly proposed ResuGlove can improve the quality of chest compressions during CPR training of laypersons and inexperienced health professionals.
- Trial name
- ResuGlove (NCT05695469)
- Testing
- Smart resuscitation glove (ResuGlove), Traditional CPR
- Where
- Finland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Turku
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