Clinical trials: Feasibility Study
Alopecia Areata
Childhood Alopecia Areata Study Using the 308-nm Excimer Laser
Alopecia Areata (AA) is a skin restricted autoimmune disease of the hair follicle, resulting in hair loss of the scalp, and in severe cases of the entire body.
- Trial name
- NCT01736007
- Testing
- 308-nm excimer laser to alopecia patch, Liquid light guide tip on laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Post-Acute COVID-19, Post Acute COVID-19 Syndrome
Safety and Dosage of a Computerized Cognitive Training Program for Cognitive Dysfunction After COVID-19
The goal of this Phase I/II clinical trial is to assess the safety and maximum tolerated training time of a self-administered computerized cognitive training (CCT) in individuals with cognitive dysfunction as a consequence of…
- Conditions
- Post-Acute COVID-19, Post Acute COVID-19 Syndrome, Cognitive Dysfunction, Cognitive Impairment
- Trial name
- CCTLongCOVID (NCT05582603)
- Testing
- CCT Long COVID
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Depression
Priming Attachment Security Within an IAPT Setting
There is growing evidence that priming attachment security is associated with improved attitudes towards therapy, increased engagement and decreased levels of depression and anxiety.
- Trial name
- NCT04022759
- Testing
- Treatment as Usual with Security Prime, Treatment as Usual (Behavioural Activation)
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Feasibility Studies
Reduction of Screen-Based Media Use in Families With Children
The purpose of this pilot experiment is threefold. 1. To assess the efficacy of the recruitment strategy 2. To assess the acceptability and feasibility of the outcome measurement methods obtained in free-living in the…
- Trial name
- NCT03788525
- Testing
- Reduced recreational screen time, Timed recreational screen time
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Physical Activity, Falls Prevention
Keeping Adults Physically Active Feasibility Study
The Keeping Adults Physically Active (KAPA) feasibility study aimed to examine the feasibility and acceptability of the an intervention designed to encourage the continuation of physical activity following the completion of a…
- Trial name
- KAPA (NCT03824015)
- Testing
- Keeping Adults Physically Active (KAPA) intervention, Usual Care
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Early Pregnancy
Doppler Assesment of Blood Flow in the Spiral Arteries
In this study we will try to show that performing Doppler of the Spiral arteries is doable. No outcome will be followed at this stage
- Trial name
- NCT01639989
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Upper Limb Deficits
Assessment of Feasibility, Functionality and Usability of an Hybrid Assistive Exoskeleton for Upper Limb
People affected by stroke or brachial plexus injuries experience huge impairment in using upper limbs for everyday life activities.
- Trial name
- NCT07000279
- Testing
- Assistive exoskeleton for activities of daily living (ADLs), Assistive exoskeleton for box and block, Assistive exoskeleton for maximum reaching height
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Dental Caries in Children
SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study
Dental caries remains a significant health problem in England, effecting 11% of 3-year-olds and 23% of 5-year- olds. Children with dental caries suffer pain, infection and poor oral health-related quality of life.
- Trial name
- NCT06092151
- Testing
- Silver diamine fluoride, Usual dental care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Symptomatic Severe Aortic Stenosis
Early Feasibility Study (EFS) of Abbott's Balloon-expandable (BE) TAVI System for the Treatment of Severe, Symptomatic Aortic Stenosis
The purpose of this study is to evaluate the safety and functionality of Abbott's BE TAVI system for the treatment of patients with symptomatic severe aortic valve stenosis.
- Trial name
- NCT07116551
- Testing
- Abbott BE TAVI System
- Where
- 5 sites in United States, France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Chronic Obstructive Pulmonary Disease (COPD), Heart Failure
Breathlessness Patterns in Patients With Cancer, COPD and Heart Failure: an fMRI Feasibility Study
Dyspnea that persists despite optimal pathophysiological treatment is defined as persistent dyspnea. Currently all brain functional magnetic resonance imaging (fMRI) studies conducted to evaluate breathlessness have done so using…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Heart Failure, Cancer, Volunteers
- Trial name
- BREACH-fMRI (NCT07319039)
- Testing
- Cerebral fMRI, Immersive virtual reality
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Hemorrhoids
The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
The investigators' aim is to assess if they can complete a study measuring the effect of local anaesthetic gel (Instillagel) on reducing pain experienced by patients undergoing a common treatment for haemorrhoids (piles).
- Trial name
- TAB (NCT04031131)
- Testing
- Instillagel, KY Gel
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Julie Dawson
Coverage of Vitamin A Supplementation, Coverage of Immunization
OPTIMIZING ROUTINE DELIVERY OF ESSENTIAL CHILD HEALTH AND NUTRITION PACKAGE THROUGH PRIMARY HEALTH CARE CONTACTS
The primary objective of the study is to assess whether optimization of an essential package of health and nutrition services for children under five years of age using vitamin A supplementation touch points (i.e., the…
- Conditions
- Coverage of Vitamin A Supplementation, Coverage of Immunization, Feasibility and Fidelity of Implementation
- Trial name
- NCT06949930
- Testing
- Optimized package of child essential health and nutrition services, Standard package of essential child and nutrition services
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 1,928 people, healthy volunteers welcome
- Sponsor
- Nutrition International
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Resilience
"resiLIR Basic": A Psychological Online Intervention to Enhance Resilience in the General Population
The goal of this clinical trial is to examine the developed online resilience intervention "resiLIR Basic" for the general population.
- Trial name
- NCT05812729
- Testing
- resiLIR Basic
- Where
- Germany
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Resilienzforschung (LIR) gGmbH
Feasibility of a Technology-based System in Aged Person
Feasibility Study of i-ACT in Aged Persons
A mix-method cross-sectional feasibility study performed in five aged care institutes in Flanders, Belgium. A convenience sample of 48 aged persons was recruited and 12 supervisors (i.e.
- Trial name
- i-ACT-aged (NCT04489563)
- Testing
- i-ACT
- Where
- 5 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- PXL University College
Older Adults
Habit Formation in Older Adults: Feasibility Study
Sedentary behavior, which is characterized by too much sitting, is an epidemic in the United States. It is estimated that 4 out of every 10 Americans never engage in physical activity, and approximately 60% of an adult's…
- Trial name
- NCT04037033
- Testing
- Everyday Meaningful Activities (EMA) intervention
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Pilot Study
How Differences in the Composition of Microorganisms in the Soil Affect the Microorganisms in the Human Gut, Through the Vegetables That Grow in it: a Process Pilot Study With Healthy Participants
There are two objectives for this clinical trial. The first is to test whether, with the current logistics and study setup it is possible to perform the study well and see where there might be bottlenecks we couldn't predict.
- Trial name
- HUMANITAS (NCT07742319)
- Testing
- Low diversity vegetable smoothie, High diversity vegetable smoothie
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Breast Cancer Female
Tissue Stresses of Cancer (Force Horizon 2020)
This project is investigating a novel MRI method called Magnetic Resonance Force (MRF). MRF has been developed to accurately estimate tumour stiffness in the breast by measuring the interstitial fluid pressure (IFP).
- Trial name
- NCT03238144
- Testing
- MRF scan
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Major Depressive Disorder
The Antidepressant Advisor (Study 3): fMRI Study to Predict Treatment Response in Patients With Depression
This prospective observational study (ADeSS-Study3) investigates candidate biomarkers prospectively predicting response to antidepressant medications and prognosis in major depressive disorder (MDD).
- Trial name
- ADeSS_S3 (NCT04342299)
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King's College London
Coronary Disease, Cardiovascular Diseases
Evaluating a Web-Based Educational Program for Adults at Risk for Coronary Heart Disease (The Heart to Heart Feasibility Study)
Coronary heart disease (CHD) is the leading cause of death in the United States, but fewer than half of all individuals at risk for CHD take advantage of proven strategies to lower their chances of developing this disease.
- Trial name
- NCT00494052
- Testing
- Heart to Heart (Web-Based Decision Aid), Physician Education Session
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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