Clinical trials: Feasibility Study
Bruxism
TMJ NextGeneration(TM) Feasibility Study
The study is an open-label, prospective, single-center, non-randomized feasibility study of the Bruxoff(TM) device to identify EMG activity associated with bruxism, and to assess the impact of the TMJ NextGeneration(TM) device…
- Trial name
- Bruxoff (NCT02257320)
- Testing
- TMJ NextGeneration(TM)
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TMJ Health
Osteoarthritis
Feasibility Study of Anti-inflammatory Cytokines in Whole Blood in Osteoarthritis Patients
This is a feasibility study to determine if anti-inflammatory cytokines can be concentrated from patients with osteoarthritis.
- Trial name
- NCT01050894
- Where
- 3 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Feasibility Studies, Physical Activity and Wellbeing
Physical Activity Intervention for Older Family Carers
The goal of this pilot trial is to learn whether a six-month physical activity program tailored for older family caregivers can be successfully delivered and whether participants are willing and able to take part in it.
- Trial name
- CAREFIT (NCT07653061)
- Testing
- Physical activity intervention for older family caregivers, Health education
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University
Stroke
Inpatient Stroke Recovery Using Sensors
This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and interpret recovery during inpatient treatment of stroke
- Trial name
- NCT04219670
- Testing
- Wearable sensors
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Hyperthermia
Sauna Detoxification Study: Pilot Feasibility
The goal of this study is to assess the feasibility of the approach, conduct a dose-finding investigation, and obtain pilot data on hyperthermia via sauna to apply in follow-up trials in the assessment of human chemical body…
- Trial name
- NCT01576822
- Testing
- This protocol will utilize a sauna as the primary method of detoxification.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Insulin Resistance, Type 2 Diabetes
Alpelisib Challenge Test (ACT)
The goal of this study is to test a potentially easier method for measuring how much insulin a person is capable of producing than the current gold-standard method, the "hyperglycemic clamp." Participants will come in for a…
- Conditions
- Insulin Resistance, Type 2 Diabetes, Obesity & Overweight, Healthy Adult Participants
- Trial name
- NCT07778524
- Testing
- Alpelisib 300 mg, Alpelisib Challenge Test (ACT): Mixed Meal Tolerance Test (MMTT) after taking alpelisib, Hyperglycemic clamp
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy, Alzheimer Disease
A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density
Up to 20 subjects will receive an injection with [11C]-UCB-J followed by a PET scan on Days 1 and 28
- Trial name
- NCT03577262
- Testing
- [11C]-UCB-J
- Where
- 3 sites in Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Obesity
Can Reverse Dieting Prevent Weight Regain After Weight Loss
Introduction: It is known that weight loss results in decreased Resting Energy Expenditure (REE), due to a decrease in lean body mass (LBM), but also due to metabolic adaptation, resulting in a higher energy efficiency…
- Trial name
- NCT03434431
- Testing
- Reverse dieting
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- George Mason University
Hepatic Disease, Renal Disease
Assess Safety and Performance of the Kronos Electrocautery Device for Electrocautery Procedures Following Coaxial Biopsy Procedures
The primary objective for this study is to assess safety and performance of the Kronos Electrocautery Device for electrocautery procedures following coaxial biopsy procedures on areas that include, but are not limited to, liver…
- Trial name
- NCT05593211
- Testing
- Kronos Electrocautery Device
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Single Pass Inc
Overweight and Obesity
Evaluating the Feasibility of a Dietary Weight Loss Program to Overcome Obesity and Its Comorbidity Among Arab Populations
This study aims to develop and test a culturally tailored online weight loss program for the Saudi population. Building upon the success of a previous program in the United States, the research team will adapt educational…
- Trial name
- NCT06415695
- Testing
- Education sessions
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asma Yahya
Abortion, Therapeutic
Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western Ukraine
The study will examine how a simplified outpatient medical abortion procedure using mifepristone and misoprostol, with the option to take mifepristone at a place of woman's choosing, works in Ukraine.
- Trial name
- NCT02981030
- Testing
- Mifepristone, Misoprostol
- Where
- 2 sites in Ukraine
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Underweight, Malnutrition
Study of Effect of Microfinance on Under 5 Health in Rural India
Investigators propose a feasibility and pilot study for a cluster randomised controlled trial. The proposed trial will evaluate the effects of an economic intervention (microfinance) in self-help groups of poor and marginalised…
- Trial name
- NCT01845545
- Testing
- Early provision of microfinance
- Where
- India
- Volunteers
- 2,469 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Neuro-Degenerative Disease, Cancer
Feasibility of Administering Clonidine as a Pharmacological Challenge in Imaging Studies
This will be a Phase 1, open label study of the pharmacokinetics (PK) and pharmacodynamics (PD) of clonidine, an alpha-2 adrenergic (a2a) agonist, in healthy volunteers.
- Trial name
- a2a Agonist (NCT04030572)
- Testing
- Clonidine Pill
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Childbirth Problems
Adapting the Stanford Obstetric Recovery Checklist in Postpartum Women to a Digital Health Platform: A Feasibility Study
Explore patient experiences engaging with a digital tool (app- and web-based) to support postpartum recovery. Postpartum recovery involves physical, emotional, and social changes, and many patients report unmet needs for timely…
- Trial name
- STORK (NCT07408557)
- Testing
- A digital application - Postpartum Companion
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Physical Inactivity
The Role of Intermediaries in Connecting Individuals to Local Physical Activity - Study Protocol
Intermediaries help people to connect to community-based services and supports, including physical activity and exercise groups (physical activities). They do this by acting as a link person.
- Trial name
- NCT06260995
- Testing
- Social Prescribing Link Worker Intermediary Intervention, Local Sports Partnership Community Development Officer Intervention
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
PTSD
Post-Deployment Afghanistan/Iraq Trauma Related Inventory of Traits (PATRIOT): Phase 1 (Feasibility Study)
The long-term goal of this research project is to identify genes that contribute to or guard against developing posttraumatic stress disorder (PTSD) and to better understand how genes and life experiences work together to impact…
- Trial name
- PATRIOT (NCT01153529)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer
Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay
Epigenomics is developing a colon cancer screening assay based on differential methylation of specific CpG sites for the detection of early stage disease.
- Trial name
- NCT00696345
- Where
- 5 sites in Germany, Hungary
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
End Stage Kidney Disease, Immunological Tolerance
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
The study seeks to determine if patients with a pre-existing, well-functioning kidney transplant from a HLA-identical living donor can be withdrawn from immunosuppressive medications without compromising allograft function…
- Conditions
- End Stage Kidney Disease, Immunological Tolerance, Kidney Transplant Failure and Rejection, Chronic Kidney Diseases
- Trial name
- NCT05525507
- Testing
- Conditioning and Stem cell infusion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Osteoarthritis
Wrist Cartilage - High Resolution in Vivo MR T2 Mapping- a Feasibility Study
Purpose:Evaluate the feasibility of T2 cartilage mapping on MRI of the wrist and correlate with T2 mapping of knee cartilage. Study protocol: Phase 1. 10 healthy volunteers, Phase 2.
- Trial name
- NCT00669201
- Where
- 2 sites in Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
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