Clinical trials: Feasibility Study
Non-valvular Atrial Fibrillation
The CONFORMAL Early Feasibility Study
An evaluation of the safety and performance of the Conformal Left Atrial Appendage Seal for Left Atrial Appendage Occlusion
- Trial name
- NCT03616028
- Testing
- left atrial appendage closure
- Where
- 11 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Conformal Medical, Inc
Healthy
Safety Study of Textile Binder for Abdominal Compression
This safety study was carried out to investigate to what extent the use of an abdominal binder influences IAP. The study was designed as a comparative cross-over study measuring bladder pressure.
- Trial name
- NCT00385892
- Testing
- Abdominal binder
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Steatosis of Liver
Liver Fat and Glucagon Resistance
One in four adults worldwide have too much fat stored in the liver which is known as metabolic associated steatotic liver disease (MASLD). This was previously known as non- alcoholic fatty liver disease (NAFLD).
- Trial name
- NCT06154096
- Testing
- Acute glucagon infusion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Healthy
Improving Night Shift Nurses' Health and Reducing Burnout
Healthy and happy nurses are essential to ensuring optimal patient outcomes and organizational success. The evidence on the negative impacts of night shift on nurses' health and cognitive function, and their implications on…
- Trial name
- NCT06829979
- Testing
- Access to napping/relaxation room, Blue and green light blocking glasses
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Vaginal Atrophy
Clinical Performance and Safety of the VITA AV Clinical System
The primary objective of this clinical investigation is to demonstrate that treatment with the VITA AV clinical system is feasible and to evaluate clinical performance and safety when used to improve the symptoms and signs of…
- Trial name
- NCT06207227
- Testing
- VITA AV Clinical System
- Where
- Georgia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AVeta Medical
Periodontitis, Gingivitis
Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools
Periodontal diseases and dental pathologies are highly prevalent oral diseases. Thirty-three to fifty percent of adult population presented at least one untreated caries and more than 50% of French population are affected by…
- Conditions
- Periodontitis, Gingivitis, Dental Caries, Diagnosis
- Trial name
- Odonto3D (NCT06006429)
- Testing
- Numerical dental impression by intraoral scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Healthy Participants
Personalized Virtual Reality for Promoting Well-Being and Psychological Flexibility in General Practitioners
General Practitioners (GPs) face significant daily challenges, and promoting their well-being is essential. In particular, psychological flexibility (PF) is a key indicator of well-being.
- Trial name
- NCT07140705
- Testing
- Transformative Virtual Reality Experience and ACT for General Practitioners
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Primary Open-angle Glaucoma
GORE Glaucoma Drainage Implant Clinical Study Dominican Republic
The objective of this early feasibility clinical study is to evaluate the safety and effectiveness of several different GORE Glaucoma Drainage Implant configurations in subjects with primary open-angle glaucoma that is…
- Trial name
- NCT05557058
- Testing
- Gore Glaucoma Device Implant (GORE GDI)
- Where
- Dominican Republic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Sedentary Lifestyle
The Engaged4Life Study: Enhancing the Health-Promoting Effects of Older Adults' Activity Portfolios
This study designs and tests a multi-component intervention- Engaged4Life- designed to enhance physical activity (PA), cognitive activity (CA), social interaction (SI) and personal meaning (PM) in low-engaged community-dwelling…
- Trial name
- NCT03337204
- Testing
- Technology-assisted self-monitoring, Workshop and Peer Mentoring
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston College
Radial Artery Cannulation
Comparative Study Between the Effect of Ultrasound Guided Median Nerve Block , Radial Nerve Block and Local Infiltration on Feasibility of Radial Artery Cannulation
Arterial line placement is often needed in various critical care settings. It is a basic procedure performed for continuous blood pressure (BP) monitoring and rapid access for repeated arterial blood gas samples, as it is…
- Trial name
- NCT05459792
- Testing
- median nerve block, radial nerve block, local infiltration
- Where
- 2 sites in Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Anxiety and Depression, Disorders of Gut-brain Interaction
Development of an Online ACT Intervention for Disorders of Gut-Brain Interaction
The goal of this clinical trial is to develop and test the iACTforDGBI intervention in a sample of Swedish individuals with DGBI (Disorders of Gut-Brain Interaction).
- Trial name
- iACTforDGBI (NCT06309004)
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Arthritis, Rheumatoid
6-Month Phase I/II Open Label PRTX-100 in Previous Rheumatoid Arthritis Study Participants and Sera Collection
Part A Primary Objective To determine the safety of six months of PRTX-100 administration. Part B Primary Objective To obtain antisera from normal volunteers that have developed anti-PRTX-100 antibodies.
- Trial name
- SPARTA-II (NCT02330445)
- Testing
- PRTX-100
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Protalex, Inc.
Breastfeeding, Breastfeeding Support
Peer-Support Breastfeeding Program for Mothers in Severe Socioeconomic Deprivation: Feasibility Study
Breastfeeding provides well-established and "irreplaceable" health benefits for both mothers and infants. However, breastfeeding rates in France remain among the lowest in Europe and are strongly associated with socioeconomic…
- Conditions
- Breastfeeding, Breastfeeding Support, Health Disparities, Health Inequalities
- Trial name
- PARTAGE (NCT07499466)
- Testing
- Peer-Support Breastfeeding Intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Aging, Healthy, Risk Reduction
The REMINDER Program for Older Adults Supported by Residential and Daycare Facilities
Dementia and mild cognitive impairment (MCI) deeply impact individuals' well-being and are expected to increase due to population aging, with global cases projected to rise to 152.8 million by 2050.
- Conditions
- Aging, Healthy, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT06733181)
- Testing
- REMINDER intervention
- Where
- Portugal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Appendix, Ultrasonography
Telementoring for Identifying the Appendix Using Telesonography
The investigators investigated the feasibility of the clinical application of novice-practitioner-performed/offsite-mentor-guided ultrasonography for identifying the appendix.
- Trial name
- TIAT (NCT02665767)
- Testing
- Smartphone-based Telesonography
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Overweight and Obesity
Evaluating the Feasibility of a Dietary Weight Loss Program to Overcome Obesity and Its Comorbidity Among Arab Populations
This study aims to develop and test a culturally tailored online weight loss program for the Saudi population. Building upon the success of a previous program in the United States, the research team will adapt educational…
- Trial name
- NCT06415695
- Testing
- Education sessions
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asma Yahya
Airway Management
Upper Airway Ultrasound Training Requirements
The applications of point-of-care ultrasonography (POCUS) of the upper airway are growing over the last decade. It's clinical applications include both diagnosis of upper airway pathology as well as pre-intubation airway…
- Trial name
- NCT05466409
- Testing
- Visualization of the hyoid bone, Visualization of vocal cords, Localization of thyrohyoid membrane
- Where
- Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Repetitive Negative Thinking
Feasibility and Preliminary Efficacy of a Web-Based Self-Help Program for College Students
The goal of this pilot study is to test the feasibility and preliminary efficacy of the repetitive negative thinking (RNT) focused web-based self-help program in college students.
- Trial name
- NCT06192056
- Testing
- RNT Focused Web- Based Self-Help Program
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Halic University
Hemorrhoids
The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
The investigators' aim is to assess if they can complete a study measuring the effect of local anaesthetic gel (Instillagel) on reducing pain experienced by patients undergoing a common treatment for haemorrhoids (piles).
- Trial name
- TAB (NCT04031131)
- Testing
- Instillagel, KY Gel
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Julie Dawson
Autism Spectrum Disorder, Parent-Child Relations
Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
The objective of this study is to conduct a pilot randomised controlled trial (RCT) evaluating the feasibility, acceptability, and preliminary efficacy of a 6-week mobile app-based intervention in empowering and supporting…
- Trial name
- NCT05927207
- Testing
- TRIP
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
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