Clinical trials: Feasibility Study
Distal Radius Fracture, Scaphoid Fracture
Acceptability and Safety of 3D Printed Wrist-based Splints
Non-invasiveness, avoidance of complications and comfort are important issues in the clinical management of conservatively treated distal radius and scaphoid fractures.
- Trial name
- 3D-splinting (NCT05075135)
- Testing
- Swibrace 3D-splint, Plaster cast
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Conjunctivitis, Glaucoma
Feasibility Study and Preliminary Application Study on Iris OCTA
All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. The main outcomes are iris blood flow density and vascular density.
- Conditions
- Conjunctivitis, Glaucoma, Myopia, Diabetic Retinopathy
- Trial name
- NCT03631108
- Testing
- OCTA (ZEISS)
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Choice Behavior
DÉCISION+, a Continuous Professional Development Program to Improve Optimal Drug Prescription : a Feasibility Study
The objective of this project is to evaluate the feasibility of a larger randomized trial of the efficacy of DECISION+, a continuous professional development program integrating multiple components, to promote shared decision…
- Trial name
- NCT00354315
- Testing
- Continuous medical education (CME)
- Where
- Canada
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Stress
Meditation to Reduce Stress and Improve Quality of Life
The purpose of this study is to test a simple meditation program that is easy to learn; inexpensive; easy to practice; non-religion based; and has wide applicability to multiple medical conditions.
- Trial name
- NCT01047917
- Testing
- Meditation DVD
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Xerostomia
Mesenchymal Stemcells for Radiation Induced Xerostomia
The current study aims to assess the safety and feasibility of the injection of autologous adipost tissue derived MSCs on radiation-induced salivary gland hypofunction and xerostomia in head and neck cancer participants.
- Trial name
- MESRIX (NCT02513238)
- Testing
- Mesenchymal stem cell, Isotonic NaCl
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Distress, Psychological, Depression - Major Depressive Disorder
Relief From Stress Via Social Protection in Senegal
Despite the growing prevalence of mental health disorders in low- and middle-income countries, significant barriers to seeking and accessing mental health services persist.
- Conditions
- Distress, Psychological, Depression - Major Depressive Disorder, Generalized Anxiety Disorder (GAD)
- Trial name
- RESTORE (NCT06698471)
- Testing
- Community worker training, Referral to Health System
- Where
- Senegal
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Pulpitis, Dental Pulp Diseases
Intentional Pulpotomy to Preserve Hopeless Molars
When proximal carious lesions of primary molars are located in close proximity to the cementum enamel junction (CEJ), marginal seal is challenging and extraction is recommended.
- Conditions
- Pulpitis, Dental Pulp Diseases, Tooth Diseases
- Trial name
- NCT04385693
- Testing
- Pulpotomy, Extraction and placement of space maintainer
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cancer Survivors, African Americans
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
This pilot study will assess the feasibility of a gratitude intervention to promote physical activity, and well-being and positively impact biomarkers of health among older African American breast cancer survivors.
- Conditions
- Cancer Survivors, African Americans, Women, Psychology, Positive
- Trial name
- NCT05473026
- Testing
- Gratitude Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Nasopharyngeal Carcinoma
To Study the Feasibility and Quality of Life of Medial Group Retropharyngeal Node Sparing in Nasopharyngeal Carcinoma
This is an randomized, controlled, phase 3 clinical trial. The purpose of this study is to evaluate whether medial group retropharyngeal node （MRLN） sparing could reduce the incidence of radiation-caused dysphagia and improve…
- Trial name
- NCT03346109
- Testing
- medial group retropharyngeal node（MRLN） sparing
- Where
- China
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Loneliness, Ageing
Physical Activity Intervention for Loneliness
The purpose of this study will be to examine the feasibility of a Physical Activity Intervention for Loneliness (PAIL) in community-dwelling older adults.
- Conditions
- Loneliness, Ageing, Physical Activity
- Trial name
- PAIL (NCT03458793)
- Testing
- Group walking and group educational workshops
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
HPV, Vaccine Acceptance
Addressing HPV Vaccine Hesitancy by Co-Designing a Digital Health Intervention
This study looks at a digital platform that supports HPV vaccination in schools. The goal is to see if it is useful, easy to use, and practical in real school settings, especially in areas where fewer people get vaccinated.
- Conditions
- HPV, Vaccine Acceptance, Vaccine Decision Making, HPV Vaccination
- Trial name
- HPV-END-IT (NCT07632963)
- Testing
- HPV-Kompassen
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Stress, Depression
Sinasprite: A Pilot Feasibility Study for Patients With Anxiety or Stress
The investigators are proposing a prospective one-arm cohort study testing the feasibility of a game designed to improve symptoms in adults with mild levels of stress, depression, and anxiety.
- Conditions
- Stress, Depression, Anxiety
- Trial name
- NCT02955784
- Testing
- Sinasprite Mobile App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Adults With Overweight and Obesity
A Feasibility Study of Mindfulness Training Transcranial Direct Current Stimulation (tDCS) in Adults With Overweight and Obesity
This study will investigate the feasibility of combining an app-based Mindfulness training (MT) with at-home administered transcranial direct current stimulation (tDCS) in adults with overweight or obesity and assess whether MT…
- Trial name
- MINDED (NCT05865912)
- Testing
- Mindfulness training + real tDCS
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King's College London
Flow Determination
Real-time Observation of Microcirculatory Hemodynamics in Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
The morphologic change of microvessels has the clinical value to distinguish cancerous from non-cancerous mucosa. The aim of this study was to observe gastric mucosa microcirculatory hemodynamic changes real-time using pCLE…
- Trial name
- NCT02595151
- Testing
- CLE
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colorectal Cancer
Feasibility, Reliability, and Satisfaction of CEA Using Home Based (Automated) Capillary Blood Sampling
The goal of this study is to determine the feasibility of CEA assessments at home using (automated) capillary sampling in patients in the follow-up after treatment for colorectal cancer.
- Trial name
- CASA-I (NCT05646030)
- Testing
- TAP-II, Lancet capillary sampling, Venipuncture
- Where
- Netherlands
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Delirium - Postoperative
Effectiveness of Electroencephalography Guided Anesthesia
This study will use brain wave information, known as electroencephalography (EEG), to help guide anesthesia delivery during surgery.
- Trial name
- EEG Anesthesia (NCT07567729)
- Testing
- EEG-guided anesthesia training program for anesthesia providers, EEG-Guided Intervention
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Stanford University
Multiple Sclerosis, Fatigue
Physiological Responses in Experimentally Induced Cognitive Fatigue in People With Multiple Sclerosis (MS)
The current study will add to the current knowledge by combining several electrophysiological techniques to examine the relationship between physiological responses and cognitive fatigue and daily activity performance in a…
- Conditions
- Multiple Sclerosis, Fatigue, Stress
- Trial name
- PREFIMS (NCT05003375)
- Testing
- High-challenging cognitive protocol to provoke stress and (cognitive) fatigue
- Where
- 2 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Alzheimer Disease
The Gut - PRO Study
The purpose of this study is to assess the safety and feasibility of an oral probiotic supplement (PS) intervention in individuals with dementia or mild-cognitive impairment (MCI) due to Alzheimer's disease or at risk of dementia…
- Trial name
- NCT07413744
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neurofibromatosis 1, Noonan Syndrome
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial
Background: RASopathies are a group of genetic diseases that affect a child s development. They cause physical, cognitive, and behavioral symptoms. Caring for a child with a RASopathy can be stressful.
- Conditions
- Neurofibromatosis 1, Noonan Syndrome, Legius Syndrome, Cardiofaciocutaneous Syndrome
- Trial name
- NCT05361811
- Testing
- Waitlist, ACT Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Infection, Coronavirus, Infections
Xofluza-Wearables Feasibility-Study
The goal of this prospective, interventional, single-center study is to assess whether the early detection of Influenza with smart wearable device algorithms and alerting, rapid testing, and subsequent Baloxavir treatment…
- Conditions
- Infection, Coronavirus, Infections, Influenza, Transplant
- Trial name
- NCT06161454
- Testing
- Baloxavir Marboxil
- Where
- United States
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
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