Clinical trials: Feasibility and Acceptability
Pregnancy Related
Feasibility and Acceptability of Butterfly iQ
The purpose of this study is to investigate feasibility and acceptability of a novel intervention to integrate Butterfly IQ into antenatal care (ANC) service delivery in Malawi.
- Trial name
- FAB-IQ (NCT05054504)
- Testing
- Butterfly iQ
- Where
- Malawi
- Volunteers
- 1,575 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Autism Spectrum Disorder
Acceptability and Efficacy of a Culturally Adapted, Low-Frequency Parent-Mediated Early Start Denver Model (ESDM) Versus Standard Care in Young Children With Autism
Early intervention is effective in improving developmental outcomes of children on the autism spectrum. However, cultural and contextual factors may influence parental acceptability of treatment models, highlighting a need for…
- Trial name
- NCT07840586
- Testing
- Early Start Denver Model
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- National University Hospital, Singapore
Schizophrenia
Exploratory Study of a Digital Therapeutics in People With Schizophrenia
CT-155 is a novel prescription digital therapeutic (PDT) being developed by Click Therapeutics, Inc. (Click) and Boehringer Ingelheim (BI) using an interactive, software-based intervention to treat schizophrenia
- Trial name
- NCT05438160
- Testing
- Clinical Learning Study smartphone app (i.e., the study app)
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Click Therapeutics, Inc.
Maternal Care Patterns
Birth Companion Intervention in Ethiopia, Kenya and Nigeria
The study aims to assess the acceptability; feasibility; implementation cost; and penetration of the birth companion intervention introduced at health facilities.
- Trial name
- NCT05565196
- Testing
- Birth companions
- Where
- 5 sites in Ethiopia, Kenya and 1 more
- Volunteers
- 10,360 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Hepatitis C, Chronic
The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study
Direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) offers a cure to those with chronic HCV infection. For marginalized communities, linkage to care services often aren't enough to overcome barriers to accessing the…
- Trial name
- NOW (NCT03987503)
- Testing
- Epclusa (SOF/VEL), Standard of care, Fibroscan® 430 Mini Plus
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Manchester Intermittent Diet in Gestational Diabetes Acceptability Study
A two-arm non-blinded randomised feasibility protocol trial designed to assess the feasibility, safety, and acceptability of an intermittent low energy diet (ILED) vs best National Health Service (NHS) care in women with…
- Conditions
- Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy, Intermittent Fasting, Pregnancy Related
- Trial name
- MIDDAS-GDM (NCT05344066)
- Testing
- Best NHS Care, Intermittent Low Energy Diet
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Parent-Child Relations, Parenting
Examine the Feasibility and Acceptability of Project Support
In this study, the investigators will conduct a proof-of-concept pilot trial of delivering the Project Support Positive Parenting Module (Project Support) to n = 30 families waiting for trauma-focused services.
- Conditions
- Parent-Child Relations, Parenting, Child Mental Disorder
- Trial name
- NCT06391229
- Testing
- Project Support
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical University of South Carolina
Physical Inactivity
Feasibility, Acceptability, and Preliminary Efficacy of a Six-week Physical Activity Intervention for Black Women
The current study will be a randomized controlled pilot study conducted in the Midwest. Participants will be randomly assigned to a behavioral intervention or a wait-list control group, each lasting six weeks.
- Trial name
- NCT05997888
- Testing
- At-Home Strength Training Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stress - Prevention of Sleep Disorders, PTSD and Depression
Solomiya App - CBT-based Self-help Intervention
The project aims to investigate the feasibility and acceptability of a smartphone intervention for depressive symptoms and insomnia in people living under prolonged stress due to the ongoing war in Ukraine.
- Trial name
- SOLOAPP-FAIT (NCT07104695)
- Testing
- Solomiya App - CBT-based self-help intervention
- Where
- Ukraine
- Volunteers
- 80 people
- Sponsor
- Solveig Kemna
Cancer
Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study
Patients living with cancer commonly have chronic pain due to the disease or to cancer treatments. Virtual reality, a new technology that immerses the user in pleasant, diverting, and exciting virtual environments, may lower…
- Trial name
- DISCOVR (NCT07228377)
- Testing
- virtual reality pain therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Type 1 Diabetes
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in Kenya.
Diabetes mellitus (diabetes) is a chronic condition that represents a major public health and clinical concern. Self-monitoring of blood glucose (SMBG) is a critical part of the care of individuals with diabetes.
- Trial name
- ACCEDE (NCT05944731)
- Testing
- Continuous glucose monitor
- Where
- Kenya
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Thoracic Aortic Disease
Accessing the Clarity and Acceptability of Recruitment Materials for a Study on Thoracic Aortic Disease Surveillance
People who are invited to take part in health research are usually given written information, such as invitation letters, and information sheets.
- Trial name
- ACCESS-TAD (NCT07574151)
- Testing
- Acceptability and Clarity
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cancer, Insomnia Chronic
Device Feasibility and Acceptability to Improve Insomnia in Cancer
Sleep disruption is common among young adult cancer survivors for a variety of reasons. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve chronic sleep disorders.
- Trial name
- NCT05875129
- Testing
- VAVA prototype
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Trachoma
App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders
Trachomatous inflammation-follicular (TF) is diagnosed by looking for clinical signs of infection of everted eyelids (conjunctivae) of children.
- Trial name
- NCT04002726
- Testing
- Inter-grader agreement (IGA) app
- Where
- Tanzania
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Depression, Anxiety
Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress
The aims of this study are to test the effectiveness and acceptability of internet-delivered treatment for depression, anxiety and stress in university students.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- EAITDAS (NCT02614443)
- Testing
- Space from Depression, Space from Anxiety, Space from Stress
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Silver Cloud Health
Survivorship
Anti-Inflammatory Lifestyle Intervention for Emerging Adult Cancer Survivors
To test the feasibility and acceptability of AILI and associated research procedures among emerging adult cancer survivors (EACS, N=16) age 18-29.
- Trial name
- HEAL (NCT06442397)
- Testing
- Anti-Inflammatory Lifestyle Intervention
- Sponsor
- Virginia Commonwealth University
Patient Participation
Using Patient Feedback in Mental Health Services
Aim: This study aims to assess how feasible and acceptable it is to deliver facilitated team meetings, designed to support mental health teams to listen and learn from patient feedback and how helpful and feasible the evaluation…
- Trial name
- NCT05603325
- Testing
- Person Centered Practice, Interview
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- NHS Grampian
Serious Illness, Existential Distress
AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness
The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the AI Assisted Personalized Legacy Program intervention to patients with serious illness.
- Trial name
- NCT07009210
- Testing
- AI Assisted Personalized Legacy Program
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic