Clinical trials: Feasibility and Acceptability
HIV-1-infection
D²EFT Graphical Informed Consent
D²EFT-GIC is a substudy of D²EFT study (NCT03017872), a randomised clinical trial of second-line antiretroviral therapies. The goal of D²EFT-GIC is to evaluate a novel tool, the "Graphical Informed Consent" (GIC), within D²EFT.
- Trial name
- D²EFT-GIC (NCT04668443)
- Testing
- Graphical Informed Consent (GIC)
- Where
- Nigeria
- Volunteers
- 12 people
- Sponsor
- Kirby Institute
Anxiety, Depression - Major Depressive Disorder
Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents
The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia…
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Burnout, Insomnia
- Trial name
- NCT07868783
- Testing
- Transcendental Meditation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Fibromyalgia, Pain
Feasibility and Acceptability of Home-based Stretching Exercises in Fibromyalgia
The study aims to gather knowledge about the patient's acceptance of the intervention and testing procedures, assess the adherence to the intervention, estimate the recruitment rate, and inform the sample size calculation for a…
- Conditions
- Fibromyalgia, Pain, Quality of Life
- Trial name
- NCT06176053
- Testing
- Homebased stretching exercise and app supervision
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University College of Northern Denmark
Alcohol Use Disorder
A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults
American emerging adults (EAs; aged 18-29 years) have the highest rates of alcohol use disorder (AUD) and the lowest levels of treatment engagement of any age group.
- Trial name
- NCT07214831
- Testing
- Large language model-based chatbot brief alcohol intervention session
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Hiv
TelePrEP for At-risk Youth in Colorado
Youth represent the largest proportion of new HIV infections in Colorado, reflective of their inadequate access and uptake of pre-exposure prophylaxis(PrEP)for HIV prevention.
- Trial name
- NCT05520905
- Testing
- TelePrEP
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autonomic Nervous System Imbalance, Heart Rate Variability (HRV)
Evaluating the Feasibility, Acceptability, and Preliminary Outcomes of Heart Rate Variability Biofeedback for Individuals With Opioid Use Disorder.
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary outcomes of a heart rate variability biofeedback (HRVB) intervention among adults with opioid use disorder (OUD) receiving residential…
- Conditions
- Autonomic Nervous System Imbalance, Heart Rate Variability (HRV), Opioid Use Disorder, Breathing Techniques
- Trial name
- NCT07361731
- Testing
- Heart rate variability biofeedback
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Arizona State University
Body Image
Evaluation of a Brief Influencer-Delivered Body Image Video
A 60-second video will be created by a high-engaging adult female influencer via a partnership with an influencer agency, Dove/Unilever, and CAR to be delivered by the same influencer to her followers on Instagram and TikTok.
- Trial name
- NCT07850037
- Testing
- Beauty on your own terms video, Neurodiversity video
- Where
- United Kingdom
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of the West of England
PrEP Uptake, Stimulant Abuse
Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).
Pepped on PrEP is an innovative pilot RCT designed by an interdisciplinary team to develop a counseling and problem-solving PrEP adherence intervention with a Behavioral Activation (BA) approach that aims to re-engage…
- Conditions
- PrEP Uptake, Stimulant Abuse, Adherence, Medication
- Trial name
- NCT03137342
- Testing
- Pepped on PrEP Package
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brown University
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood
Feasibility and Acceptability of Remote Saliva Collection
The purpose of this study is to evaluate the practicality and acceptability of collecting biological samples and health information from childhood survivors of acute lymphoblastic leukemia (ALL) and their siblings.
- Trial name
- NCT07884474
- Testing
- Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Caregivers
Feasibility and Acceptability of an LLM-based Chatbot for Family Caregivers: Evaluation Study
This study evaluates the feasibility and acceptability of using the artificial intelligence (AI) chatbot mobile application (an LLM-based Chatbot) to support the well-being of informal care partners of individuals with traumatic…
- Trial name
- NCT07280650
- Testing
- LLM-based Chatbot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Alcohol Use Disorder, Substance Use Disorders
A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use
The purpose of this study is to compare the feasibility, acceptability, and efficacy of a dialectical behavior therapy skills training webapp known as "Pocket Skills" in outpatients and community members seeking treatment for…
- Trial name
- NCT05094440
- Testing
- Dialectical behavioral therapy skills training (DBT-ST)
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Centre for Addiction and Mental Health
Obesity & Overweight, Emotional Eating
Online Group Programme on Mindful Eating During Medication-Supported Weight Loss
The goal of this clinical trial is to evaluate the feasibility and acceptability of a digitally delivered, mindfulness-based nutrition group program for adults with obesity who are taking GLP-1 receptor agonist medication and…
- Conditions
- Obesity & Overweight, Emotional Eating, Emotional Eating Behaviour, Online Intervention
- Trial name
- NCT07701291
- Testing
- Online Group Intervention on Mindful Eating
- Volunteers
- 28 people
- Sponsor
- Bern University of Applied Sciences
Depressive Symptoms, Major Depressive Disorder
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology
The primary aim of this pilot study is to assess the feasibility, acceptability, and preliminary evidence of efficacy of a self-guided, cognitive behavioral therapy (CBT)-based mobile app intervention (SparkRx) for symptoms of…
- Conditions
- Depressive Symptoms, Major Depressive Disorder, Depression, Cardiology
- Trial name
- NCT05461599
- Testing
- SparkRx Mobile App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Limbix Health, Inc.
Bereavement
Cultural Adaptation of a Self-help App for Grieving Syrian Refugees in Switzerland
The goal of this pilot RCT is to investigate the acceptability and feasibility of an unguided culturally adapted self-help app for grieving Syrian refugees in Switzerland.
- Trial name
- NCT06246708
- Testing
- Self-help app with information for grieving Syrian Refugees, Wait-list
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Abortion, First Trimester
Acceptability and Feasibility of a Simplified Medical Abortion Regimen in Georgia
This study examined the acceptability and feasibility of using a simplified regimen of medical abortion in the eastern and western regions of the country of Georgia.
- Trial name
- NCT02398838
- Testing
- Home administration of 200 mg mifepristone, Home or clinic administration of 400 mcg buccal misoprostol
- Where
- 4 sites in Georgia
- Volunteers
- 622 people
- Sponsor
- Gynuity Health Projects
Depression, Anxiety
Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress
The aims of this study are to test the effectiveness and acceptability of internet-delivered treatment for depression, anxiety and stress in university students.
- Conditions
- Depression, Anxiety, Stress
- Trial name
- EAITDAS (NCT02614443)
- Testing
- Space from Depression, Space from Anxiety, Space from Stress
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Silver Cloud Health
Suicide
The INSPiRe Programme: Developing an Intensive Suicide Prevention Therapy for Suicidal Prisoners
This study aims to assess the acceptability and feasibility of a short-term, intensive Cognitive Behavioural Therapy (CBT) delivered to male prisoners who have thoughts of ending their lives.
- Trial name
- NCT03499548
- Testing
- INSPiRe Programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Manchester
Loneliness
Establishing Social Connections in Urban Areas: Evaluating a Community-based Programme
The aim of this study is to evaluate the feasibility and acceptability of a new community-based programme designed to tackle loneliness for young and working-age adults.
- Trial name
- NCT06805136
- Testing
- Community-based social interaction intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- Queen Mary University of London
Psychosis, Suicidal
Acceptability and Feasibility of MOL in Acute Inpatient Units
The current study aims to test the acceptability and feasibility of a psychological therapy called Method of Levels (MOL) as an intervention for people in acute psychiatric inpatient units who are experiencing psychosis and/or…
- Trial name
- NCT05377294
- Testing
- Method of Levels therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester