Clinical trials: Fecal Continence Disorders
Urinary Tract Infections
Quick-Wee Versus Bladder Stimulation System to Collect Midstream Urine From Pre-continent Infants
Urinary tract infections are common in infants. Obtaining urine from pre-continent children can be difficult and time consuming.
- Trial name
- ES-Stimquick U (NCT04587999)
- Testing
- bladder stimulation, Quick wee
- Where
- 3 sites in Canada, France
- Volunteers
- 230 people
- Sponsor
- Fondation Lenval
Neurogenic Bladder, Continent Cutaneous Urinary Diversion
Implantation of Continent Catheterizable Channel : Native Bladder or Enterocystoplasty ?
PURPOSE. To compare the results between two sites of implantation of the continent catheterizable channel (CCC): native bladder or enterocystoplasty. METHODS.
- Conditions
- Neurogenic Bladder, Continent Cutaneous Urinary Diversion, Mitrofanoff
- Trial name
- ICODE (NCT04922437)
- Testing
- Native bladder implantation, Enterocystoplasty implantation
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Central Hospital, Nancy, France
Incontinence, Overactive Bladder, Stress Urinary Incontinence
Investigation of the Suburothelial Myofibroblast Network and of Smooth Muscle Function and Control in the Human Urinary Outflow Tract
The aim is to find out if adreno-muscarinic synergy is present also in human tissues of the urinary outflow tract that have a dual adrenergic-muscarinic receptor fitting.
- Trial name
- NCT01227447
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Prostate Cancer, Post Prostatectomy Incontinence
Anatomical and Functional Differences Between Continent and Incontinent Men Post Radical Prostatectomy
One out of every six men will be diagnosed with prostate cancer and post prostatectomy up to 75% report urinary incontinence. There are many hypotheses about the exact cause of post prostatectomy stress incontinence (PPI).
- Trial name
- NCT01832831
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Urinary Incontinence, Urinary Incontinence, Stress
Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women
Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence (UI), Urinary Bladder, Overactive
- Trial name
- SE-inc1 (NCT06933407)
- Testing
- Strain Elastography
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
Inflammatory Bowel Diseases, Anorectal Malformations
StoMakker Mobile Application
The goal of this clinical trial is to investigate if access to the StoMakker application will significantly improve health-related quality of life in children receiving surgery resulting in an ileostomy, colostomy or continent…
- Conditions
- Inflammatory Bowel Diseases, Anorectal Malformations, Spina Bifida, Ostomy
- Trial name
- StoMakker (NCT06065995)
- Testing
- StoMakker
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Bladder Exstrophy
Long-term Outcomes of Patients Treated for Bladder Exstrophy by Questionnaires.
The bladder exstrophy epispadias complex (BEEC) is a rare spectrum of congenital conditions due to abnormal development of the cloacal membrane.
- Trial name
- QUALEXSTRO (NCT05690594)
- Testing
- Self or straight administered questionnaire
- Where
- 2 sites in France
- Volunteers
- 42 people
- Sponsor
- Hospices Civils de Lyon
Spina Bifida, Neurogenic Bowel
Bowel Continence Across the Lifespan in People With Spina Bifida
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida.
- Conditions
- Spina Bifida, Neurogenic Bowel, Bowel Incontinence
- Trial name
- BCALS (NCT07390318)
- Testing
- Retrograde Enema, Antegrade Enema
- Where
- 24 sites in United States
- Volunteers
- 943 people
- Sponsor
- David Chu
Urinary Tract Infections
Clean Catch Urine Feasibility and Contamination Rate Compared to Bladder Catheterization Urine in Pre-Continent Children
Introduction: Urinary tract infections (UTIs) are a common source of infection in children, accounting for a significant proportion of visits every year.
- Trial name
- NCT06265142
- Testing
- Bladder catheterization, clean catch urine via bladder massage technique
- Volunteers
- 80 people
- Sponsor
- Oman Medical Speciality Board
Spinal Cord Injuries, Urinary Diversion
Efficacy and Safety of a Continent Cutaneous Urinary Diversion in Spinal Cord Injury Patients
Continent Cutaneous Urinary Deviation (CUD), using the Mitrofanoff, Yang-Monti or Casale principle, is offered to patients with neurological diseases who are unable to perform intermittent catheterisation through the native…
- Conditions
- Spinal Cord Injuries, Urinary Diversion, Neurogenic Bladder
- Trial name
- ELESDUCCBM (NCT04936217)
- Testing
- Data collection, Interview using a validated questionnaire
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Rectal neoplasia is one of the most prevalent cancers in Spain, and the treatment of choice is total mesorectal excision (TME), as it has demonstrated significant oncological improvements.
- Conditions
- Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant, Quality of Life (QOL), Fecal Incontinence (FI)
- Trial name
- NCT07632196
- Testing
- Posterior tibial nerve stimulation intervention group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Fecal Incontinence
Mechanisms of Improving Fecal Continence Muscles Motor Function
The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles…
- Trial name
- NCT06532123
- Testing
- continence muscles resistance device
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Fecal Continence Disorders, Posterior Pelvic Static Disorders
Fecal Incontinence and Rectal Static Disorder
This study evaluate the rate of occurrence of fecal incontinence in patients who had surgery for posterior pelvic static disorder versus those with medical management.
- Trial name
- NATUROSTATIQ (NCT04566640)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Rennes University Hospital
Fecal Incontinence, Faecal Incontinence
FENIX™ Continence Restoration System Registry
The FENIX Registry is a multi-center, observational database designed to collect data regarding the FENIX™ Continence Restoration System in everyday clinical practice, evaluate the clinical course of patients from pre-operative…
- Trial name
- NCT04007250
- Testing
- FENIX™ Continence Restoration System
- Where
- 2 sites in France, Germany
- Volunteers
- 94 people
- Sponsor
- Torax Medical Incorporated
Fecal Incontinence, Inflammatory Bowel Disease (IBD)
Faecal Incontinence iNtervention Study
Inflammatory Bowel Disease (IBD) affects 250,000 adults in the United Kingdom (UK) and causes bouts of diarrhoea which are hard to control. Over a quarter of patients experience extremely distressing faecal incontinence (FI).
- Trial name
- FINS (NCT02355834)
- Testing
- IBD nurse intervention
- Where
- 6 sites in United Kingdom
- Volunteers
- 67 people
- Sponsor
- London North West Healthcare NHS Trust
Rectal Neoplasms, Colostomy Stoma
Pseudo Continent Perineal Colostomy vs Permanent Left Iliac Colostomy After Abdominoperineal Resection for Ultra Low Rectal Adenocarcinoma
Aim of this study is to compare the cost-effectiveness and the quality of life in the 6 months following the surgery of a pseudo continent perineal colostomy (PCPC) and a permanent left iliac colostomy (PLIC) following an…
- Conditions
- Rectal Neoplasms, Colostomy Stoma, Quality of Life
- Trial name
- NCT04141566
- Testing
- Perineal pseudocontinent colostomy, Permanent left iliac colostomy
- Where
- Morocco
- Volunteers
- 35 people
- Sponsor
- Moroccan Society of Surgery
Bladder Calculi, Continent Catheterizable Urinary Reservoir
Comparison of Trans-Stomial Bladder Lithotripsy Using Mini-Percutaneous Equipment Versus Trans-stomial Bladder Lithotripsy Using Flexible Fibroscope, Percutaneous Approach and Open Cystolithotomy in Patients With Continent Catheterizable Urinary Reservoir
The urological management of neurological patients is crucial to ensure patient survival and improve their quality of life. The natural progression of disease in central neurological bladders typically involves a major decrease…
- Conditions
- Bladder Calculi, Continent Catheterizable Urinary Reservoir, Trans-Stomal Bladder Lithotripsy, Open Cystolithotomy
- Trial name
- Mini-DUCC (NCT07643454)
- Testing
- QoL-DUCC questionnaire, Qualiveen Questionnaire
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Rectal Neoplasms, Fecal Incontinence
The Role of Biofeedback in Improving Continence After Anterior Resection
The purpose of this study is to determine whether biofeedback exercises improve anal continence after anterior resection for rectal cancer.
- Conditions
- Rectal Neoplasms, Fecal Incontinence, Aged
- Trial name
- NCT00515853
- Testing
- Biofeedback
- Where
- United Kingdom
- Volunteers
- 121 people
- Sponsor
- University of Southampton
Fecal Incontinence, Bowel Dysfunction
LIBERATE - PRO: Eclipse™ System Registry
A prospective, open label post market registry to collect Patient Reported Outcomes in an online data capture registry, maintained by Pelvalon, of women with fecal incontinence exiting the LIBERATE study (NCT02428595) continuing…
- Conditions
- Fecal Incontinence, Bowel Dysfunction, Bowel Incontinence, Accidental Bowel Leakage
- Trial name
- LIBERATEPRO (NCT03028636)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pelvalon, Inc.
Overactive Bladder
Efficacy and Safety Study of Botulinum Toxin Type-A (Dysport®) in Continent Female Subjects Suffering From Idiopathic Overactive Bladder
The purpose of this study is to determine the optimal dose of botulinum toxin type A injected in the detrusor muscle to improve urinary symptoms, urodynamic parameters and quality of life of continent women suffering from…
- Trial name
- NCT00578097
- Testing
- Botulinum toxin type A
- Where
- 34 sites in Belgium, Czechia and 6 more
- Volunteers
- 81 people
- Sponsor
- Ipsen