Clinical trials: Fecal Incontinence (FI)
Fecal Incontinence (FI)
Safety and Feasibility Evaluation of ALVIV Laser Based Treatment for Fecal Incontinence
The purpose if this interventional First in Human study is to assess the Safety and Performance of the ALVIV System laser based treatment in patients diagnosed with Fecal Incontinence.
- Trial name
- NCT07436676
- Testing
- ALVIV Laser Treatment
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Alviv Ltd.
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Evaluation of the new Axonics External Trial System (ETS-02) in patients with overactive bladder (OAB) and/or fecal incontinence (FI).
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
- Trial name
- NCT07335484
- Testing
- Axonics External Trial System (ETS)
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- Axonics, Inc.
Fecal Incontinence (FI), Anorectal Malformations
Effectiveness of Electrical Stimulation and Biofeedback on Fecal Incontinence in Children With Repaired Anorectal Malformation
This study aimed to investigate and compare the effect of electrical stimulation and biofeedback with electrical stimulation alone on fecal incontinence in children with repaired imperforate anus, with ages from 6 to 10 years.
- Trial name
- NCT07366476
- Testing
- behavioral therapy, biofeedback, electrical stimulation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sinai University
Fecal Incontinence
A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Fecal incontinence is the involuntary leakage of stool from the anus. Doctors at Mayo Clinic are doing a research study to assess the effects of a medication, clonidine, on fecal incontinence and rectal functions in women.
- Trial name
- NCT00884832
- Testing
- Clonidine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Normal Subjects, Fecal Incontinence
Trial to Evaluate Fecobionics in Fecal Incontinence (FI) (NORMAL and ABNORMAL-FI)
The objective is to determine the length-tension properties of the anal sphincters using Fecobionics in normal subjects and FI patients during anal distension and during simulated evacuation.
- Trial name
- NCT05412069
- Testing
- Fecobionics
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Faecal Incontinence, Faecal Incontinence With Faecal Urgency
UCon Treatment of the Symptoms of Faecal Incontinence (FI)
UCon is a medical device for treatment of the symptoms of overactive bladder and fecal incontinence (FI). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature e.g.…
- Trial name
- NCT05864807
- Testing
- UCon
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- InnoCon Medical
Fecal Incontinence, Irritable Bowel Syndrome With Diarrhea
The Role of Fiber in the Prevention and Treatment of Fecal Incontinence
The purpose of this study is to determine the effect of fiber supplementation on the fecal metagenome and metabolome in relation to symptoms and anorectal physiology in post-menopausal women with irritable bowel syndrome with…
- Trial name
- NCT04806386
- Testing
- Psyllium
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Massachusetts General Hospital
Fecal Incontinence
Translumbosacral Neuromodulation for FI
Fecal Incontinence (FI) affects 40 million Americans, predominantly women and elderly. It is a major health care burden, significantly impairs quality of life and psychosocial function.
- Trial name
- TNT (NCT03899181)
- Testing
- Translumbosacral Neuromodulation Therapy (TNT)
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Augusta University
Fecal Incontinence (FI), Healthy Female Volunteer
Dose-Efficacy of rTMS in Healthy Young Female Volunteers
This study is aimed to develop a new therapy based on non-invasive repetitive magnetic stimulation rehabilitation for FI in patients who do not respond to conventional therapies.
- Trial name
- NCT07192328
- Testing
- rTMS and rTLSMS administered using a Magstim Rapid2 repetitive stimulator at pre-identified hotspots (cortical, lumbar, and sacral regions bilaterally).
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital de Mataró
Fecal Incontinence, Inflammatory Bowel Disease (IBD)
Faecal Incontinence iNtervention Study
Inflammatory Bowel Disease (IBD) affects 250,000 adults in the United Kingdom (UK) and causes bouts of diarrhoea which are hard to control. Over a quarter of patients experience extremely distressing faecal incontinence (FI).
- Trial name
- FINS (NCT02355834)
- Testing
- IBD nurse intervention
- Where
- 6 sites in United Kingdom
- Volunteers
- 67 people
- Sponsor
- London North West Healthcare NHS Trust
Fecal Incontinence
Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fecal Incontinence
Single-Arm, multi-center, prospective, open-label registry study for commercially available rechargeable implantable neurostimulator (INS model 5101); also referred to as R20.
- Trial name
- NCT07499258
- Testing
- Axonics SNM System INS Model 5101 (R20)
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 55 people
- Sponsor
- Axonics, Inc.
Accidental Bowel Leakage, Fecal Incontinence
Diet and Fecal Incontinence in Senior Women
Investigators will conduct a single-arm pre-post intervention pilot study in 46 older women with Fecal Incontinence (FI), also known as Accidental Bowel Leakage (ABL).
- Conditions
- Accidental Bowel Leakage, Fecal Incontinence, Incontinence, Bowel Incontinence
- Trial name
- NCT03510052
- Testing
- Diet Modification Pilot Program (DPM)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Pennsylvania
MRI in Evaluation of Fecal Incontinence
Fecal Incontinence (FI) is a Debilitating Physical and Psychological Disorder Characterizedbytheinvoluntary Loss of Flatus or Liquid/Solid Stool.
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool.
- Trial name
- NCT07898748
- Testing
- 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fecal Incontinence
A Prospective, Multi-center, Randomized, Blinded Study to Evaluate Durasphere FI for the Treatment of Fecal Incontinence
The purpose of this study is to evaluate a new injectable bulking agent for the treatment of fecal incontinence in adult men and women.
- Trial name
- NCT00762047
- Testing
- Durasphere FI
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Carbon Medical Technologies
Fecal Incontinence (FI), Anorectal Malformations
Effect of Pudendal Nerve Electrical Stimulation on Fecal Incontinence in Children With Repaired Anorectal Malformation
This randomized controlled clinical trial aims to evaluate the effect of pudendal nerve electrical stimulation on fecal incontinence in children with repaired anorectal malformation.
- Trial name
- NCT07099339
- Testing
- Behavioral Therapy, Kegel Exercise, Pudendal Nerve Electrical Stimulation
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Sinai University
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
F15 Recharge Free Axonics SNM System Clinical Study
Multicenter, prospective, non randomized, single arm evaluation of patients with overactive bladder (OAB) and/or fecal incontinence (FI) employing the Axonics recharge free SNM System.
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI)
- Trial name
- NCT06186765
- Testing
- Axonics SNM System (Model 4101)
- Where
- 16 sites in United States, Netherlands and 1 more
- Volunteers
- 144 people
- Sponsor
- Axonics, Inc.
Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Rectal neoplasia is one of the most prevalent cancers in Spain, and the treatment of choice is total mesorectal excision (TME), as it has demonstrated significant oncological improvements.
- Conditions
- Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant, Quality of Life (QOL), Fecal Incontinence (FI)
- Trial name
- NCT07632196
- Testing
- Posterior tibial nerve stimulation intervention group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Fecal Incontinence
Diet and Stool Metabolites in Fecal Incontinence
Fecal Incontinence (FI) is a debilitating and common condition with a prevalence ranging from 7-15% in community dwelling women.
- Trial name
- NCT02485522
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania