Clinical trials: Fecal Incontinence and Constipation
Irritation; Anus
Validation of TRansanal Irrigation Adherence scaLe (TRIAL)
Transanal irrigation (TAI) is a method used to empty stools from the recto-sigmoid and colon (from the descending colon to the transverse colon).
- Trial name
- NCT06805903
- Testing
- TRansanal Irrigation Adherence scaLe
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries, Constipation
Pharmacokinetics of Neostigmine and Glycopyrrolate
A group of 6 able-bodied healthy volunteers will receive Neostigmine (NEO) and Glycopyrrolate (GLY) intravenously and via 2 methods of Iontophoresis (ION): one-patch and two-patch administration, with subsequent blood draws over…
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT04027972
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Functional Colonic Disease, Fecal Incontinence
Effect of Lumbo-sacral Magnetic Stimulation on Colonic Motility
The purpose of this study is to evaluate the effect of sacral nerve magnetic stimulation on the colonic motility in healthy subjects, in incontinent and constipated patients.
- Trial name
- NCT00213317
- Testing
- lombo-sacral magnetic stimulation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Multiple Sclerosis, Anorectal Disorders
Effect of Need to Void on Rectal Sensory Function in Multiple Sclerosis
Multiple sclerosis causes demyelinating lesions, which can induce multiple symptoms. Ano-rectal avec urinary disorders are frequent due to specific lesions in inhibitor/activator encephalic centers, or interruption on medullary…
- Conditions
- Multiple Sclerosis, Anorectal Disorders, Bladder Dysfunction
- Trial name
- NCT04057222
- Testing
- No intervention
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Gérard Amarenco
Painful Bladder Syndrome, Interstitial Cystitis
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Purpose: 1. To demonstrate better symptoms control (pain, urinary urgency and frequency) with sacral neuromodulation (SNM) in patients with interstitial cystitis /painful bladder syndrome (IC/PBS) using a stimulation frequency of…
- Conditions
- Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction
- Trial name
- NCT01312259
- Testing
- Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Pelvic and Sexual Health Institute
Defecation Disorder, Constipation - Functional
Barriers to Rectal Irrigation in Defaecatory Dysfunction
Rectal irrigation is the introduction of warm tap water through the anal canal into the rectum to initiate defaecation. NICE recommends that rectal irrigation be considered in patients with constipation(1) and faecal incontinence…
- Conditions
- Defecation Disorder, Constipation - Functional, Constipation by Outlet Obstruction, Faecal Incontinence
- Trial name
- NCT06569446
- Testing
- There is no intervention. This a qualitative study to explore barriers to rectal irrigation
- Volunteers
- 34 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Abdominal Pain, Deglutition Disorders
Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes
Healthcare delivery now mandates shorter visits with higher documentation requirements, undermining the patient-provider interaction.
- Conditions
- Abdominal Pain, Deglutition Disorders, Fecal Incontinence, Nausea
- Trial name
- AEGIS (NCT02530216)
- Testing
- AEGIS (Automated Evaluation of Gastrointestinal Symptoms)
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Cedars-Sinai Medical Center
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Multiple Sclerosis, Constipation
Symptoms and Treatment Assessment of Ano-Rectal Disorders in Multiple Sclerosis Patients : STAR-Q
Multiple sclerosis (MS) is known to cause urinary disorders, sexual and bowel dysfunction. Urinary symptoms due to MS are well known and profit of multiple questionnaire or tool developed in MS patients.
- Conditions
- Multiple Sclerosis, Constipation, Fecal Incontinence
- Trial name
- STAR-Q (NCT04996186)
- Testing
- Clinical interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Pierre and Marie Curie University
Constipation
Biofeedback for Dyssynergic Constipation
Constipation affects 4% of adults in the United States (U.S.). An estimated half of constipated patients are unable to relax pelvic floor muscles during defecation, a type of constipation called pelvic floor dyssynergia (PFD).
- Trial name
- NCT00127257
- Testing
- Biofeedback, Diazepam, Pelvic floor retraining
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Encopresis
Internet-based Treatment of Early Childhood Fecal Incontinence
Encopresis, also known as fecal incontinence, is the voluntary or involuntary passage of stools causing soiling of clothes by a child over 4 years of age.
- Trial name
- NCT00067769
- Testing
- Internet-based intervention UCanPoopToo, treatment as usual
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Constipation Aggravated, Fecal Incontinence With Fecal Urgency
A Comparison of Quality of Life Between MAlone Procedure and Percutaneaous Endoscopic Caecostomy in Patients With Antegrade Colonic Enema
Background: Antegrade colonic enema (ACE) is a second intent treatment of severe constipation and/or fecal incontinence following the failure of medical treatment.
- Trial name
- MAPEC (NCT05040139)
- Testing
- Malone Procedure, Percutaneous endoscopic caecostomy
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Nantes University Hospital