Clinical trials: Feeding; Difficult, Newborn
Prader-Willi Syndrome
PWS European Blood Bank for Infants and Controls From 0 to 48 Months
The present project aims to determine the underlying mechanisms for the switch from failure to thrive to excessive weight gain and hyperphagia with impaired satiety in PWS.
- Trial name
- NCT02529085
- Testing
- blood samples
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Body Composition, Feeding; Difficult, Newborn
Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty
Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment.
- Conditions
- Body Composition, Feeding; Difficult, Newborn, Nutrition Disorder, Infant
- Trial name
- NCT04599010
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Breastfeeding, Ankyloglossia
Physiotherapy in the Treatment of Breastfeeding Difficulties
The objective of this randomized, single-blind clinical trial is to compare the efficacy of two treatments (Myofunctional Therapy and breastfeeding sessions) in infants who have difficulty breastfeeding during the first week of…
- Conditions
- Breastfeeding, Ankyloglossia, Lactation Disorders
- Trial name
- NCT05843279
- Testing
- Myofunctional therapy
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad de Almeria
Premature Infant Sleep
Sleep Organization in Premature Infants With Feeding Difficulties
Babies born too soon, premature babies, can have complications following birth because their systems are immature. Hospitals help prevent deformities and delays in motor development by using therapeutic positioning to provide…
- Trial name
- NCT01946308
- Testing
- Conformational positioning system
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Infant,Premature, Feeding; Difficult, Newborn
Nifty Feeding Cup Versus Generic Medicine Cup Preterm Infants Who Have Difficulty Breastfeeding
The investigators will establish an evidence base for the Nifty Feeding Cup by evaluating its effectiveness and caregiver satisfaction.
- Trial name
- NCT03280381
- Testing
- Nifty feeding cup, Generic medicine cup
- Where
- Ghana
- Volunteers
- 200 people
- Sponsor
- PATH
Immaturity, Oral Intolerance
Effect of Kangaroo Care on Heart Rate Variability
Physiological processes leading to a preterm infant to be able to feed orally has not been fully understood. The investigators hypothesized that maturation of autonomic nervous system may play a major role in this process and…
- Conditions
- Immaturity, Oral Intolerance, Postnatal Adaptation
- Trial name
- NCT01865409
- Testing
- Kangaroo Care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih University
Swallowing Disorder, Perinatal Asphyxia
Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia
The transition period to full oral feeding in infants with perinatal asphyxia is important in predicting long-term outcomes. The transition to independent oral feeding is accepted as a discharge criterion by the American Academy…
- Conditions
- Swallowing Disorder, Perinatal Asphyxia, Feeding; Difficult, Newborn, Feeding Disorder of Infancy or Early Childhood
- Trial name
- NCT05687708
- Testing
- Non-Nutritive Sucking
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medipol University
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Feeding Disorder Neonatal
Feasibility of Aerodigestive Stimulation Therapy Trial
The goal of this study is to demonstrate safety, feasibility, and efficacy of a novel pharyngo-esophageal stimulation technique in restoring aerodigestive and swallowing functions in select infants at-risk for chronic gavage tube…
- Trial name
- FAST (NCT06118697)
- Testing
- Esophageal stimulation with high resolution esophageal manometry and nutritive oral feeding therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sudarshan Jadcherla
Congenital Disorders
Feeding After Neonate Surgery Review
The purpose is to determine what factors, if any, lead to delayed feeding, discharge with a NG tube, G-tube placement or Nissen fundoplication.
- Trial name
- NCT00229866
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Healthcare of Atlanta
Treatment Failure, Lethargy
RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia
Burden: Pneumonia remains the leading infectious cause of death accounting for 920,000 children under five around the world. This means a loss of over 2,500 child lives every day, or over 100 every hour.
- Conditions
- Treatment Failure, Lethargy, Altered Mental Status, Convulsion, Non-Epileptic
- Trial name
- NCT03369093
- Testing
- Amoxicillin
- Where
- Bangladesh
- Volunteers
- 308 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Dysphagia of Newborn
The Effects of Pacifier-Activated Lullaby on Oral Feeding Among Preterm Infants
Preterm infants often have difficulty learning how to feed by mouth because the coordination of sucking, swallowing, and breathing develops later in pregnancy.
- Trial name
- Music therapy (NCT07819734)
- Testing
- Pacifier-Activated Lullaby (PAL) Therapy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Stunting, Wasting
Weight Patterns in the Month After Birth
This is a prospective cohort study that will be conducted in four low income countries to describe newborn weight patterns in the first month after birth and their association with clinical and demographic factors including…
- Conditions
- Stunting, Wasting, Undernutrition, Feeding Patterns
- Trial name
- NCT04025827
- Testing
- Dietary intake
- Where
- 5 sites in United States, Guinea-Bissau and 3 more
- Volunteers
- 741 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neonatal Encephalopathy, Feeding; Difficult, Newborn
OMT to Improve Feeding After Hypothermia
The goal of this study is to determine if infants with neonatal encephalopathy will achieve full oral feeds faster after therapeutic hypothermia has completed if they are treated with osteopathic manipulative treatment.
- Trial name
- NCT03380013
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
Premature Birth, Breastfeeding, Exclusive
taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge
Investigators aim to improve the skills of premature or sick term infants in breastfeeding by boosting motor learning with transcutaneous vagus nerve stimulation.
- Conditions
- Premature Birth, Breastfeeding, Exclusive, Feeding; Difficult, Newborn
- Trial name
- NCT06417385
- Testing
- taVNS soterix device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Feeding; Difficult, Newborn, Necrotizing Enterocolitis
A Multi-strain Synbiotic Versus a Multi-strain Probiotic in Premature Infants
The aims are to 1) compare two probiotic treatments (multi-strain synbiotic vs. multi-strain probiotic) on bifidobacteria fecal colonization counts at 1, 2, 3, and 4 weeks of life, 34 weeks corrected gestation age (CGA) ; 2)…
- Trial name
- NCT01337921
- Testing
- Multi-strain Probiotic
- Sponsor
- University of Nebraska
Premature Birth, Feeding; Difficult, Newborn
Effects of a Valved Feeding System in Late-preterm Newborns: the Safe Oral Feeding Trial
Comparing with a randomized controlled trial two different feeding systems in two groups of late-preterm newborns for evaluating which is more efficient in promoting the coordination in the process of sucking-swallowing-breathing…
- Conditions
- Premature Birth, Feeding; Difficult, Newborn, Feeding, Bottle
- Trial name
- SOFT (NCT04400175)
- Testing
- Valved ergonomic teat, Standard silicon teat
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy
Congenital Heart Disease
The Efficacy of Systematic Oral Feeding Education Program
After the intervention of Systematic Oral Feeding Education Program: 1. The feeding techniques scores of the main caregivers in the experimental group will be higher than those in the control group. 2.
- Trial name
- SOFEP (NCT06763497)
- Testing
- Systematic Oral Feeding Education Program
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Swallowing Dysfunction
Promotion of Thickened Feeds to Manage Newborns With Feeding Difficulties
Swallowing dysfunction and delay of oral feeding skills in premature infants significantly delay discharge from the hospital. Thickening oral formula or breast milk feeds with commercial thickeners and rice cereal has been used…
- Trial name
- NCT00859092
- Testing
- Simply Thick
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- David Oelberg, M.D.