Clinical trials: Female Contraception
Uterine Bleeding Profile Prediction
A Study to Learn More About How a Smartphone App Called MyIUS Predicts Future Menstrual Bleeding in Women After They Have Begun Using Intrauterine Birth Control Method (a Birth Control Device is Inserted Into a Woman's Uterus by Her Doctor)
Researchers are looking to learn more about future menstrual bleeding in women who have started using intrauterine contraception methods.
- Trial name
- MyIUS (NCT04989595)
- Testing
- MyIUS app
- Where
- 6 sites in Brazil, Denmark and 4 more
- Volunteers
- 3,045 people, healthy volunteers welcome
- Sponsor
- Bayer
Hiv, Contraception
Mobile Phone Messaging to Improve Reproductive Health for Women Living With HIV in Kenya (Mobile WACh Empower)
Use of a mobile health (mHealth) intervention to provide reproductive life counseling to women living with HIV may improve delivery of integrated reproductive health/HIV services and prevent adverse reproductive health outcomes.
- Conditions
- Hiv, Contraception, Fertility Issues
- Trial name
- NCT05285670
- Testing
- Digital counseling plus interactive two-way SMS dialogue
- Where
- 10 sites in Kenya
- Volunteers
- 3,310 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - LNG
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- EC-Obesity (NCT02863445)
- Testing
- Levonorgestrel-based emergency contraception 1.5 mg, Levonorgestrel-based emergency contraception 3.0mg
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Study Investigating the Efficacy and Safety of a Contraceptive Patch for 13 Cycles
This study is examining a birth control patch for 13 cycles (1 year).
- Trial name
- NCT00910637
- Testing
- Gestodene/EE Patch (BAY86-5016)
- Where
- 63 sites in United States
- Volunteers
- 1,502 people, healthy volunteers welcome
- Sponsor
- Bayer
Fetal Alcohol Spectrum Disorders, Pregnancy
CARRII Native Intervention Optimization Trial
The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP).
- Conditions
- Fetal Alcohol Spectrum Disorders, Pregnancy, Alcohol-Related Disorders, Drinking, Alcohol
- Trial name
- NCT07547696
- Testing
- CARRII Native Cores
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pregnancy, Breastfeeding
The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months
The study's purpose is to determine if early (2-3 week) versus traditional (6-8 week) postpartum follow up is associated with a higher rate of breastfeeding at 6 months.
- Conditions
- Pregnancy, Breastfeeding, Contraception, Cervical Cancer
- Trial name
- NCT02221895
- Testing
- Postpartum follow up appointment 2-3 weeks after delivery, Postpartum follow up 6-8wk after delivery
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Contraception
Non-interventional, Real Life Study on Satisfaction With LNG-IUS in Spanish Young Women (18-30 Years Old) With Different Parity Status and Menstrual Bleeding Pattern
The aim of this non-interventional study (NIS) is to assess, under real-life conditions, woman's satisfaction with Levonogestrel IntraUterine System (LNG-IUS) in a young (18-30 years old (y.o.)) Spanish population taking into…
- Trial name
- BERTA (NCT03493295)
- Testing
- Levonogestrel IntraUterine System (LNG-IUS)
- Where
- Spain
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Sayana® Press Self-injection Study in Malawi
The feasibility of Sayana Press self-injection and the potential for this practice to increase contraceptive continuation has never been assessed in family planning programs in low-resource settings.
- Trial name
- NCT02293694
- Testing
- Sayana Press
- Where
- Malawi
- Volunteers
- 735 people, healthy volunteers welcome
- Sponsor
- FHI 360
Female Contraception
Bioequivalence Study of Patches With Different Release Profiles
The purpose of this study was to determine the bioequivalence of a norelgestromin/ethinyl estradiol (NGMN/EE) transdermal contraceptive system.
- Trial name
- NCT00697307
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Vaginosis, Bacterial
Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers
It is not known if the use of NuvaRing® alters these innate and inflammatory biomarkers of inflammation. Hypothesis: The hypothesis is that NuvaRing® will alter inflammatory biomarkers of inflammation, such as vaginal defensin…
- Trial name
- NCT01448291
- Testing
- Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Contraception, Obesity
Pharmacokinetics of Implanon in Obese Women
Prior studies examining the pharmacokinetics, safety, and efficacy of the new etonogestrel-containing single rod implantable contraceptive device, Implanon, did not include women who exceeded 130% of ideal body weight.
- Trial name
- NCT00724438
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Contraceptive Usage
Assess Performance Attributes and Acceptability of Non-medicated Intravaginal Rings Among Sexually Active Women in Atlanta, GA
A randomized open label crossover trial to assess performance attributes and acceptability of non-medicated intravaginal rings among sexually active women in Atlanta, GA
- Trial name
- NCT07039591
- Testing
- Pro-type IVR
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Population Council
Hiv, Contraception Behavior
TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use
The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia.
- Trial name
- NCT06852508
- Testing
- TwySHE
- Where
- Zambia
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Opioid Use Disorder
Sex and Female Empowerment
This study will develop and initially evaluate Sex and Female Empowerment (SAFE), an intervention designed to increase acceptance of and adherence to contraceptive practices among opioid-agonist-maintained women of childbearing…
- Trial name
- SAFE (NCT02197715)
- Testing
- Computer-adaptive SAFE, Face-to-face SAFE, Usual Care
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Contraception
Spermicidal Efficacy Of A Vaginal Gel
There is an urgent need to develop non-hormonal innovative preventive measures under the control of women that can prevent unintended pregnancy.
- Trial name
- NCT03833115
- Testing
- vaginal gel containing or not sodium lauryl sulfate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Contraception
Thorough QT/QTc Study of Multiple Oral Doses of NOMAC-E2 (Org 10486 0 + Org 2317) in Healthy Women (Study 292011)(P05802)
The trial is a single-center randomized, double-blind, double-dummy, placebo and positive controlled, parallel group clinical trial.
- Trial name
- NCT00779532
- Testing
- Moxifloxacin, NOMAC-E2 (Org 10486-0 + Org 2317)
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Diabetes Mellitus, Type 2
A Research Study Looking Into the Effect of Semaglutide and NNC0480 0389 on Blood Levels of a Birth Control Pill in Woman After Menopause
Novo Nordisk is developing a combination therapy with the investigational drug NNC0480-0389 and an already approved medicine called "semaglutide" for the treatment of type-2 diabetes (T2D).
- Trial name
- NCT05153564
- Testing
- Semaglutide 1.34 mg/mL, Semaglutide 3.0 mg/mL, NNC0480-0389 10 mg/mL
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
HIV, Immune Cells (Mucosal and Systemic)
Quantification of Immune Cells in Women Using Contraception (CHIC II)
This study is being done to understand if using birth control causes changes in the immune cells within the reproductive tract (including the cervix and the lining of the uterus) of healthy women.
- Conditions
- HIV, Immune Cells (Mucosal and Systemic), Contraception
- Trial name
- CHIC-II (NCT01873170)
- Testing
- levonorgestrel exposure, DMPA exposure, etonogestrel exposure
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Contraception
Contraceptive Effectiveness of Sino-implant (II) in China
A cohort study to Evaluate the contraceptive effectiveness of Sino-implant (II) during the 3rd and 4th years of use in Chinese women
- Trial name
- NCT01936454
- Where
- 5 sites in China
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- FHI 360
Pharmacokinetics, Therapeutic Equivalency
Bioequivalence Study of the Oral Contraceptive (OC) Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.
The purpose of the study is to determine the bioequivalence of Norgestimate (NGM) and Ethinyl Estradiol (EE) in 2 formulations of 250 mcg NGM/25 mcg EE, 1 without folic acid and 1 containing 400 mcg folic acid.
- Conditions
- Pharmacokinetics, Therapeutic Equivalency, Contraceptives, Oral
- Trial name
- NCT00709644
- Testing
- Norgestimate; Ethinyl Estradiol; Folic acid.
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.