Clinical trials: Female Contraception
HIV Infections
AmbassADDOrs for Health Study
The goal of the study is to evaluate Malkia Klabu ("Queen Club") in Tanzania, a loyalty program intervention that creates adolescent girls and young women (AGYW)-friendly drug shops where AGYW can access HIV prevention services…
- Trial name
- ADDO (NCT05357144)
- Testing
- Loyalty card program at drug shops & supply of HIVST and SRH products, Comparison drug shops
- Where
- 2 sites in Tanzania
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
YAZ, Oral Contraceptive Registration in China
The purpose of this study is to evaluate the effectiveness in terms of prevention of pregnancy and safety of the oral contraceptive YAZ in healthy Chinese women.
- Trial name
- NCT00819312
- Testing
- YAZ (SH T00186, BAY86-5300)
- Where
- 17 sites in China, Hong Kong
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Bayer
Postpartum Contraception
Effect of Joint Provision of Community Group-based Counseling with Individual Counseling on Postpartum Contraception
The aim of this trial is to assess the effectiveness of joint provision of community group-based demonstration counseling methods with routine individual family planning counseling provided to prenatal and postnatal women on…
- Trial name
- NCT06766409
- Testing
- A community group-based demonstration counseling method, An individual family planning counseling
- Where
- Ethiopia
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Contraception
GA Levonorgestrel Intrauterine Contraceptive System (LCS) Phase III Study China
The purpose of this study is to assess the efficacy, safety, bleeding pattern of low dose LNG (12 mg/ 24 hrs), delivered locally by a new intrauterine contraceptive system suitable for use by women 18 to 40 years of age.
- Trial name
- NCT00884260
- Testing
- Levonorgestrel IUS (LCS, BAY86-5028)
- Where
- 25 sites in Australia, China and 1 more
- Volunteers
- 918 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Women, Female Contraception
Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard
This will be a multi-site, participant-blinded, randomized clinical trial. The investigators will randomize 1000 eligible participants in a 4:1 ratio to two different copper IUDs: 800 to Mona Lisa NT Cu380 Mini and 200 to…
- Trial name
- NCT03124160
- Testing
- Mona Lisa® NT Cu380 Mini, ParaGard® TCu380A
- Where
- 16 sites in United States
- Volunteers
- 1,105 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraception, Sexually Transmitted Infections
Connecting Healthy Women: Examining the Effect of an Intervention From the Effect of Being Reachable
The investigators propose to test a community-developed and targeted intervention that employs community health workers (CHWs) as aides to newly Medicaid-insured women.
- Conditions
- Contraception, Sexually Transmitted Infections, Cervical Cancer
- Trial name
- NCT02157168
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 2,267 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Bacterial Vaginosis, HIV
The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis
The proposed study, Hormonal Contraception \& BV (HCBV), will investigate the effect of NET-EN and DMPA on recurrent BV, vaginal microbiota and inflammatory markers among women at high risk for HIV in Kampala, Uganda.
- Trial name
- HCBV (NCT02905890)
- Testing
- Norethisterone enantate, Condoms
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Contraception, Breastfeeding
Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial
The investigators goal is to measure the impact of timing of postpartum contraceptive implant insertion on breastfeeding success and duration and to explore women's experiences with and attitudes towards contraceptive and…
- Conditions
- Contraception, Breastfeeding, Postpartum Contraception
- Trial name
- NCT02866279
- Testing
- Etonogestrel Contraceptive Implant
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Contraception, Pain
The Effect of Nitroglycerin on the Intrauterine Device (IUD) Insertion Experience in Nulliparous Women
Increasing ease of access of long-acting birth control methods, like intrauterine devices (IUDs), is an important way to reduce the risk of unintended pregnancy.
- Trial name
- NCT01490073
- Testing
- Insertion of nitroglycerin ointment
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraceptive Usage, HIV Infections
Effect of Dolutegravir on Etonogestrel Levels in HIV-infected Women in Botswana
The primary aim is to assess if etonogestrel (ENG) implant users taking dolutegravir (DTG) have a 20% or greater change in their ENG plasma levels, compared to women taking no antiretroviral therapy (ART).
- Conditions
- Contraceptive Usage, HIV Infections, Drug Interaction
- Trial name
- NCT03336346
- Testing
- dolutegravir, ENG implant, Efavirenz
- Where
- Botswana
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Columbia University
Contraception, Menopause
Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers
Estetrol (E4) is being developed in two indications supporting women health care: first E4 is combined with a progestin, [drospirenone (DRSP)] and is used as a new combined oral contraceptive (COC) for the prevention of pregnancy…
- Trial name
- NCT03075956
- Testing
- 5 mg E4 single-dose, 15 mg E4 single-dose, 45 mg E4 single-dose
- Where
- Bulgaria
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Estetra
Anemia
Levonorgestrel Intrauterine System Effects on Hemoglobin and Serum Ferritin Among Anemic Women in Kenya
Women with mild/moderate anemia who are seeking contraception will be randomized to a levonorgestrel (LNG) intrauterine system (IUS) or an LNG/ethinyl estradiol (EE)/ferrous fumarate combined oral contraceptive (COC) regimen and…
- Trial name
- LISA (NCT05233956)
- Testing
- LNG IUS, COCs
- Where
- Kenya
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- FHI 360
Contraceptive Usage
A Phase I Study to Evaluate the PK and PD of a Single Injection of Levonorgestrel Butanoate for Female Contraception
To evaluate the levonorgestrel (LNG) pharmacokinetic (PK) profile following injection of a single 20 mg dose of levonorgestrel butanoate (LB).
- Trial name
- CCN011 (NCT02173808)
- Testing
- levonorgestrel butanoate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Premier Research
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Contraception
Investigation of Three Contraceptive Hormone Patches in Regard to Inhibition of Ovulation Following Application Over 3 Treatment Cycles in Healthy, Young Women.
The primary objective of this trial is to examine whether ovulation is suppressed after use of hormone patches containing different dosages of ethinyl estradiol (EE) and gestodene (GSD) for 3 treatment cycles.
- Trial name
- NCT01204190
- Testing
- Gestodene/EE Patch (BAY86-5016)
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Efficacy and Safety of a Combined Oral Contraceptive of Estradiol Valerate and Dienogest in Healthy Female Subjects
To evaluate the efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in healthy female subjects.
- Trial name
- NCT01638910
- Testing
- EV/DNG (Qlaira, BAY86-5027)
- Where
- 39 sites in China, Hong Kong and 3 more
- Volunteers
- 955 people, healthy volunteers welcome
- Sponsor
- Bayer
Women, Contraception
Annovera™ Drug-Drug Interaction Study
A Drug-Drug Interaction (DDI) study to evaluate the effects of itraconazole and rifampin on the Pharmacokinetics of Segesterone Acetate and Ethinyl Estradiol from the Annovera Contraceptive Vaginal System (CVS)
- Trial name
- NCT04290390
- Testing
- Segesterone Acetate and Ethinyl Estradiol, Rifampin, Itraconazole
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- TherapeuticsMD
Contraception, Contraception Behavior
Patient-Centered Reproductive Decision Support Tool for Women Veterans
The investigators have developed a web-based decision support tool to help women Veterans get the information and care they need to achieve their reproductive goals, whether that includes optimizing their health before desired…
- Conditions
- Contraception, Contraception Behavior, Prepregnancy Health, Reproductive Health
- Trial name
- MyPath (NCT04584294)
- Testing
- MyPath Web-Based Informational and Decision Support Tool
- Where
- 12 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Contraception
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)
The purpose of this study is to assess the contraceptive efficacy of the Etonogestrel (ENG) + 17β-Estradiol (E2) vaginal ring in women between 18 and 35 years of age based on the number of in-treatment pregnancies as expressed by…
- Trial name
- NCT02524288
- Testing
- ENG-E2 125 μg/300 μg vaginal ring
- Volunteers
- 1,941 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Prenatal Care Late, Contraceptive Usage
Community-based Provision of Urine Pregnancy Tests as Linkage to Reproductive Health Services
Kenyan families experience persistently high rates of maternal and neonatal mortality, which disproportionately affects women with low income and education and those who live far from health services.
- Conditions
- Prenatal Care Late, Contraceptive Usage, Pregnancy Complication
- Trial name
- NCT03626597
- Testing
- Urine Pregnancy Test, CHV-based post-test counseling & referral, Phone-based post-test counseling & referral
- Where
- Kenya
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Indiana University