Clinical trials: Female Contraception
Contraception
LCS12 Adolescent Study
The study will assess the safety of a sex hormone (levonorgestrel) releasing T-shaped intrauterine contraceptive system in female adolescents under 18 years of age.
- Trial name
- NCT01434160
- Testing
- Skyla (Levonorgestrel, BAY86-5028)
- Where
- 41 sites in Austria, Belgium and 6 more
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Investigate Impact of Yasmin vs Microgynon on Hemostasis Parameters in Healthy Women
The objective of this study was to investigate the impact of the oral contraceptive YASMIN (containing: drospirenone 3 mg/ethinyl estradiol 30 mcg) in comparison with the oral contraceptive MICROGYNON (containing: levonorgestrel…
- Trial name
- NCT00651846
- Testing
- Yasmin (DRSP 3mg/EE 0.03 mg), Microgynon (LNG 0.15 mg/EE 0.03 mg)
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bayer
Insulin Sensitivity, Cardiovascular Risk
Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women
Birth control pills are the most commonly used method of birth control. The purpose of this research study is to examine whether birth control pills change heart disease risk and how the body handles blood sugar when given to…
- Conditions
- Insulin Sensitivity, Cardiovascular Risk, Perimenopausal Disorder
- Trial name
- NCT01475513
- Testing
- Ortho Cyclen®
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Contraception
Kenya Sino-implant (II) PK Study
A cross-sectional study to compare pharmacokinetics of Sino-implant (II) during four years of used and Jadelle during five years of use by Kenyan women.
- Trial name
- NCT01930994
- Where
- Kenya
- Volunteers
- healthy volunteers welcome
- Sponsor
- FHI 360
Contraceptive Devices, Long-Acting Reversible Contraception
Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women
This pilot study aims to assess the feasibility, acceptability, and effectiveness of using nitrous oxide (N2O) sedation for intrauterine device (IUD) insertions for nulliparous adolescent and young adult women in a primary care…
- Conditions
- Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health
- Trial name
- NCT04089852
- Testing
- Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Sterility, Female, Contraception
Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization
More than 345,000 U.S. women undergo either tubal ligation ("getting her tubes tied") or Essure procedures each year to permanently avoid pregnancy.
- Conditions
- Sterility, Female, Contraception, Contraceptive Device; Complications
- Trial name
- NCT03438682
- Testing
- Essure, Laparoscopic sterilization, Intrauterine Device (IUD)
- Where
- United States
- Volunteers
- 89,203 people, healthy volunteers welcome
- Sponsor
- Yale University
Contraception Behavior
Debunking Myths About Contraceptive Safety Among Women in Kingston, Jamaica
The primary hypothesis is that the intervention video - based on strategies from cognitive psychology - can correct women's misinformation about long-acting reversible contraception (LARC) and result in higher use of LARC.
- Trial name
- NCT03775642
- Testing
- Intervention video, Control video
- Where
- Jamaica
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Contraception
A Study to Compare 3 Doses of a Hormonal Intra-uterine Device Containing Levonorgestrel and Indomethacin With a Hormonal Intra-uterine Device Containing Only Levonorgestrel to Assess the Effect and Safety of the Combined Components
This study is the first study investigating the combined intrauterine administration of LNG (levonorgestrel) and IND (indomethacin). It is a combined proof-of-concept (PoC) and dose finding (DF) study in pre-menopausal women.
- Trial name
- INDessa (NCT03562624)
- Testing
- BAY98-7443, Levonogestrel (Skyla, BAY86-5028)
- Where
- 7 sites in Germany, United Kingdom
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Bayer
Hormonal Contraception
Contraceptive Hormones, Immunity, and Microbiome Evaluation
The study is a prospective cohort study to explore the mechanisms underlying the HIV risk associated with pharmacologic doses of exogenous sex hormones via hormonal contraceptives specially progestin-containing hormonal…
- Trial name
- CHIME (NCT03660046)
- Testing
- Depot medroxyprogesterone acetate (DMPA), Etonogestrel implant (Eng-Implant), Levonorgestrel IUD (Lng-IUD)
- Where
- 3 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Emory University
Contraception
A Study to Evaluate Inhibition of Ovulation of Two Oral Estrogen/Progestogen Regimens in Healthy, Young Females Over a Period of 3 Treatment Cycles
Investigation of a new pill containing an estrogen and a progestin in order to monitor the inhibition of the ovulation in young healthy females over 3 treatment cycles
- Trial name
- NCT00631124
- Testing
- BAY86-4891 (Estradiol / Drospirenone)
- Where
- 2 sites in Germany
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
A Trial of Group Versus Individual Family Planning Counseling in Ghana
This study uses a randomized, noninferiority design to determine whether group family planning counseling is as effective as individual family planning counseling among gynecological patients with unmet need at two teaching…
- Trial name
- GCFP (NCT00814411)
- Testing
- group family planning counseling, Individual family planning counseling
- Where
- 3 sites in United States, Ghana
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Contraceptive Device; Complications
The Contraceptive Efficacy and Safety of an Intravaginal Acetic Acid Thermoreversible Gel on Chinese Women.
The study aims to explore the efficacy and safety of an intravaginal acetic acid thermoreversible gel in Chinese women of reproductive age, comparing it with nonoxinol gel by assessing the six-month Pearl Index and the incidence…
- Trial name
- contraception (NCT06203080)
- Testing
- ancetate gel, nonoxinol gel
- Where
- 4 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Contraception Behavior, Contraception
The Influence of Trust in the Health Care System on Postpartum Contraceptive Choice
The purpose of this research is to understand the relationship between trust in the health care system and choice of contraception during the postpartum period among pregnant women receiving prenatal care.
- Trial name
- NCT02213874
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Female Contraception
Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive
Participants in the study will use mifepristone 50 mg once-a-week for one year as a contraceptive. With this, we want to confirm that the chances of getting pregnant while using this contraceptive are very small.
- Trial name
- WOMEN&More (NCT06394999)
- Testing
- Mifepristone 50 mg
- Where
- 14 sites in Netherlands
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Focus: Contraceptive Counseling, Focus: Postpartum Contraception
Investigating the Effect of a Prenatal Family Planning Counseling Intervention Led by Community Health Workers on Postpartum Contraceptive Use Among Women in the West Bank
The purpose of this study is to measure the difference in proportion of postpartum women using contraception after a Community Health Worker (CHW) family planning educational intervention compared to women who receive standard…
- Trial name
- NCT01854671
- Testing
- family planning counseling let by community health workers
- Where
- Palestinian Territories
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Contraception: Optional Applicator for Insertion of Vaginal Ring
Performance and Safety of Vaginal Ring Applicator in Healthy Females (MK-8342A-063)
The purpose of the study is to assess the performance and safe use of the vaginal ring applicator as an optional aid for insertion of a placebo vaginal ring into the vagina in healthy women
- Trial name
- NCT02275546
- Testing
- Single-use, non-sterile applicator
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Organon and Co
IUD, Analgesia
TENS Unit for Analgesia During IUD Insertion
Subjects will be screened over the phone or in Tufts GYN clinic for participation in the study. If eligible and interested in participating, written informed consent (and assent if applicable) will be obtained.
- Conditions
- IUD, Analgesia, Patient Preference, Pain, Acute
- Trial name
- NCT06240260
- Testing
- TENS (transcutaneous electrical nerve stimulation) unit, Standard care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Healthy
A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)
The primary purpose of this trial is to assess the pharmacokinetic profile of NOMAC, E2 and E1 after multiple and single dose administration of the combined oral contraceptive NOMAC-E2
- Trial name
- NCT00711607
- Testing
- nomegestrol acetate and estradiol
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Study to Investigate Efficacy and Safety of a New Oral Contraceptive
The purpose of this study is to evaluate the safety and effectiveness of a new 4-phasic preparation in the prevention of pregnancies in a large group of volunteers.
- Trial name
- NCT00185289
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K)
- Where
- 50 sites in Austria, Germany and 1 more
- Volunteers
- 1,392 people, healthy volunteers welcome
- Sponsor
- Bayer