Clinical trials: Female Contraception
Contraception
A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom
WHAT IS THE FEMALE CONDOM? The female condom being examined in this study is investigational (experimental) and is not yet approved by the Food and Drug Administration (FDA).
- Trial name
- NCT01223313
- Testing
- Woman's Condom
- Where
- 10 sites in United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Premier Research
Obesity
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - LNG
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- EC-Obesity (NCT02863445)
- Testing
- Levonorgestrel-based emergency contraception 1.5 mg, Levonorgestrel-based emergency contraception 3.0mg
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
A Study to Evaluate the Pharmacokinetics (PK) of Medroxyprogesterone Acetate Following an Injection of TV-46046 in Healthy Women of Reproductive Age
The primary objective of this study is to evaluate and compare the pharmacokinetic profile of Medroxyprogesterone acetate following subcutaneous administration of 3 different doses of TV-46046 and a dose of Depo-subQ Provera in…
- Trial name
- NCT04682353
- Testing
- TV-46046, Depo-subQ Provera
- Where
- 3 sites in United States, Dominican Republic
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Contraception, Menopause
Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol
This study is being conducted to further understand the elimination pathways, metabolite profile and pharmacokinetic (PK) profile of carbon 14 labelled estetrol ([14C] estetrol).
- Trial name
- NCT02720224
- Testing
- Estetrol
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Estetra
Contraception
Study to Evaluate Cycle Control With Norgestimate/Ethinyl Estradiol and Drospirenone/Ethinyl Estradiol in Healthy Sexually Active Females
The purpose of this study in healthy sexually active females is to evaluate the cycle control with norgestimate/ethinyl estradiol versus drospirenone/ethinyl estradiol.
- Trial name
- NCT00745901
- Testing
- Norgestimate/ethinyl estradiol; Drospirenone/ethinyl estradiol
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Contraception
Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel
This study will determine the effects of St. John's wort, a common herbal remedy, on metabolism of the female contraceptive hormone levonorgestrel.
- Trial name
- NCT00131885
- Testing
- St. John's Wort, Levonorgestrel
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hemostasis, Oral Contraceptive
A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women
This study is being conducted to evaluate the impact of a 91-day extended cycle oral contraceptive compared to two 28-day oral contraceptive regimens on hemostatic parameters in healthy women.
- Trial name
- NCT01252186
- Testing
- 91-day Levonorgestrel Oral Contraceptive, 28-day Levonorgestrel Oral Contraceptive, 28-day Desogestrel Oral Contraceptive
- Where
- 24 sites in United States, Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Teva Women's Health
Contraception
E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada Study
The objectives of this study are to evaluate the contraceptive efficacy, vaginal bleeding pattern (cycle control), and the general safety and acceptability of the 15 mg estetrol (E4)/3 mg drospirenone (DRSP) combination in…
- Trial name
- NCT02817841
- Testing
- 15 mg E4/3 mg DRSP
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,148 people, healthy volunteers welcome
- Sponsor
- Estetra
Postpartum
Home-based Delivery of the Contraceptive Implant in Postpartum Guatemalan Women
Abstract Background: Postpartum contraception is important to prevent unintended and closely spaced pregnancies following childbirth.
- Trial name
- NCT04005391
- Testing
- Offer of Participant's Choice of Contraception Method
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sterilization, Female, Fallopian Tube Occlusion
Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion
The overarching goal of this study is to find an alternative method to hysterosalpingogram (HSG) to confirm bilateral tubal occlusion after permanent contraception.
- Trial name
- NCT04071392
- Testing
- Hysterosalpingogram (HSG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cystitis, Interstitial, Dysmenorrhea
Chronic Pain Risk Associated With Menstrual Period Pain
The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic…
- Conditions
- Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain
- Trial name
- CRAMPP (NCT02214550)
- Testing
- cyclic microgestin 1/20, continuous microgestin 1/20
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Contraception
A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)
The primary objective of this trial was to identify at least one next generation ring (NGR) that demonstrates inhibition of ovulation (which was considered confirmed if in the subset of participants ovulation was observed in less…
- Trial name
- NCT01709318
- Testing
- Nomegestrol acetate (NOMAC), Etonogestrel (ENG), Ethinyl estradiol (EE)
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Obesity, Contraception
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- UPA-Obesity (NCT02859337)
- Testing
- UPA-ECx1, UPA-ECx2
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Genital Tract Mucosal Immunity, Genital Tract Microflora
Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception
This pilot study is being performed to investigate the influence that starting contraception with an IUD has on the local immune cell populations and features, with a particular focus on the cells and cell-surface features that…
- Trial name
- CHIC (NCT01240811)
- Testing
- IUD placement, Levonorgestrel IUD, Copper T380A IUD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sharon Achilles
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Abnormal Uterine Bleeding, Unspecified, Uterine Bleeding Heavy
Treatment of Unacceptable Bleeding Patterns in ETG Implant Users With an Oral Contraceptive
This double-blinded, placebo-controlled, randomized trial will compare the effects of the use of a combined oral contraceptive pill to a placebo pill for women who are experiencing irregular and/or heavy bleeding associated with…
- Trial name
- ROBI (NCT01963403)
- Testing
- EE 30mcg/LNG 150mcg
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of California, Davis
Contraception
Dose-finding Study for the Ultralow-dose Levonorgestrel Intrauterine Contraceptive System (LCS)
The purpose of this study is to investigate if drug doses lower than the one released from Mirena® would be as effective for contraception as Mirena®.
- Trial name
- NCT00185380
- Testing
- Levonorgestrel IUS (BAY86-5028, G04209B), Levonorgestrel IUS (BAY86-5028, G04209C), Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- 35 sites in Finland, Hungary and 3 more
- Volunteers
- 742 people
- Sponsor
- Bayer
HIV, Contraception
Reaching Adolescent Girls and Young Women Through Girl-Friendly Drug Vendors
We will pilot an intervention to deliver sexual and reproductive health services, including HIV self-testing (HIVST) and contraception, to adolescent girls and young women (AGYW) at accredited drug dispensing outlets (ADDOs) in…
- Trial name
- NCT04045912
- Testing
- AGYW-Friendly Services, HIVST
- Where
- Tanzania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception, Inhalation of Nitrous Oxide
Nitrous Oxide for Pain Management During In-office Transcervical Sterilization
This is a randomized, double blind study that aims to measure the difference in maximum pain experienced during in-office transcervical sterilization (Essure®) for women receiving either inhaled nitrous oxide or standard oral…
- Trial name
- NEST (NCT02312739)
- Testing
- In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pregnancy Prevention
A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy
This is an open-label, single-treatment study. All subjects will receive 12 months of oral contraceptive therapy with DR-103. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT00996580
- Testing
- DR-103
- Where
- 94 sites in United States
- Volunteers
- 3,597 people, healthy volunteers welcome
- Sponsor
- Teva Women's Health