Clinical trials: Female Fertility
Childhood Cancer, Fertility Issues
Addressing Fertility Information Needs and Distress
The purpose of this study is to develop and refine a behavioral intervention to address fertility-related information needs and fertility-related distress among female adult survivors of childhood cancer.
- Trial name
- NCT06834945
- Testing
- AYA SPARK
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Pelvic Organ Prolapse, Pelvic Floor Prolapse
Laparoscopic Lateral Suspension With Mesh & Sacrocervicopexy for the Treatment of Uterine Prolapse
This study is aimed to compare the efficiency of two uterus-preserving laparoscopic methods to treat uterine prolapse in a randomized controlled trial.
- Trial name
- NCT03421457
- Testing
- Uterus-preserving laparoscopic lateral suspension with mesh, Uterus-preserving laparoscopic sacrocervicopexy with mesh
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Infertility, Female, Premature Ovarian Failure
Second Step Protocol in Poor Ovarian Responder (POR)
Reduced ovarian reserve and the consequent poor ovarian response are very recurent in infertile patients, indeed a percentage of 10%-24% of couples addressed to infertility program may be classified as Poor Ovarian Responder…
- Conditions
- Infertility, Female, Premature Ovarian Failure, Fertility Disorders
- Trial name
- POR (NCT03480412)
- Testing
- Follicular Phase, Luteal Phase
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Chronic Endometritis, Uterus; Scar
Fertility Restoration Using Autologous Mesenchymal Stem Cells
Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the…
- Conditions
- Chronic Endometritis, Uterus; Scar, Uterine Synechiae, Fallopian Tube Obstruction
- Trial name
- NCT04432467
- Testing
- Autologous mesenchymal stem cells, standard treatment
- Where
- Belarus
- Volunteers
- 10 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Fertility-Sparing Treatment (FST), Atypical Endometrial Hyperplasia
Ultrasound and Histology in AEH and Early EEC Treated Conservatively
Ultra-S.A.F.E. is a multicenter, ambispective observational study investigating the ultrasound and histological characteristics of patients with atypical endometrial hyperplasia (AEH) or endometrioid endometrial carcinoma (EEC)…
- Conditions
- Fertility-Sparing Treatment (FST), Atypical Endometrial Hyperplasia, Early Endometrial Cancer (EEC)
- Trial name
- ULTRA-SAFE (NCT07028242)
- Testing
- Hysteroscopic fertility-sparing surgery and hormonal treatment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometritis, Infertility
Fertility Outcomes After Antibiotic Treatment In Women With Chronic Endometritis
Chronic endometritis (CE) is a long-lasting inflammation of the lining of the uterus. Many women with CE do not have symptoms, but the condition may affect fertility, embryo implantation, and pregnancy outcomes.
- Conditions
- Endometritis, Infertility, Hysteroscopy, Pregnancy Disease
- Trial name
- MORE (NCT07603492)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
PCOS
Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility
The study aimed to assess how a 6-month insulin sensitizer therapy impacts insulin resistance, glucose tolerance, and hormonal levels in women with PCOS.
- Trial name
- NCT07058675
- Testing
- Metformin Hydrochloride 500 MG, Myoinositol
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Endometriosis
Laparoscopy Versus Laparotomy for Colorectal Endometriosis
Study hypothesis: equivalency of laparoscopic compared to laparotomic colorectal resection for endometriosis on digestive, gynaecologic, general symptoms and quality of life.
- Trial name
- NCT00939861
- Testing
- laparoscopy, laparotomy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Tenon Hospital, Paris
Infertility
Food Intake Among Women and Men in Fertility Treatment
Worldwide infertility is highly prevalent and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment.
- Trial name
- Food&Fertility (NCT05454046)
- Testing
- Food intake among women and men in fertility treatment
- Where
- 8 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Aalborg University Hospital
Female Fertility and Bariatric Surgery
Female Fertility Outcome Following Bariatric Surgery: Five Years Follow up
Maternal morbid obesity is an important risk factor in modern obstetrics, it has been associated with higher infertility rates and obstetrics complications.
- Trial name
- NCT04392661
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 197 people
- Sponsor
- Tanta University
Breast Cancer - Female, Fertility
Fertility Decision and Outcomes in Young Women With Breast Cancer
This observational study is to learn about the fertility outcomes and decision after breast cancer diagnosis, and the current status of fertility consultation and decision support in young women diagnosed with breast cancer in…
- Trial name
- NCT07804745
- Testing
- No intervention (observational study)
- Where
- 3 sites in China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cervical Cancer
Prospective Study of Fertility-sparing Treatment Strategy in Patients With Early Cervical Cancer(SYSUGO-005/CSEM009)
Patients with cervical cancer staging IB1-IIA2 desiring keeping their fertility function will be recruited. Before treatment, MRI scanning will be used to exclude retroperitoneal lymph node metastasis, involvement of lower part…
- Trial name
- SYSUGO-005 (NCT02624531)
- Testing
- Taxane, radical trachelectomy
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Hemoglobin, Stem Cell Transplant
Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
Background: Some treatments for cancer or other diseases can lead to infertility in women. These treatments include chemotherapy, some stem cell transplants, and pelvic radiotherapy. They are called gonadotoxic therapies.
- Conditions
- Hemoglobin, Stem Cell Transplant, Aplastic Anemia
- Trial name
- NCT02225145
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Infertility, Miscarriage
International NaProTechnology Evaluation and Surveillance of Treatment for Infertility and Miscarriage (iNEST)
NaProTechnology (NPT) is a treatment option for infertility or miscarriage that identifies issues in a couple's fertility and fixes them to the extent possible by medical intervention.
- Trial name
- iNEST (NCT01363596)
- Testing
- Creighton Model System in conjunction with Natural Procreative Technology (NPT)
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 834 people
- Sponsor
- University of Utah
Preterm Birth, Gestational Diabetes Mellitus (GDM)
Evaluation of Maternal and Neonatal Outcomes in Women Are Conceived Through Assisted Reproductive Technology Compared to Other Fertility Treatments and Naturally Conceived Women: It is a Retrospective Cohort Study Conducted Over a 5-year Period at a Fertility Center in a Lebanese Hospital
Background: The number of couples experiencing difficulties conceiving and seeking treatment for infertility has increased dramatically over time.
- Conditions
- Preterm Birth, Gestational Diabetes Mellitus (GDM), Gestational Hypertension
- Trial name
- non (NCT06836843)
- Testing
- Since this is an observational study rather than an interventional study, the exposure type refers to all potential factors influencing pregnancy both before and during pregnancy
- Where
- Lebanon
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Lebanese University
IVF, Body Weight
Nutritional Status of Women Undergoing in Vitro Fertilization
Infertility affects around 15 % of couples in their reproductive years. Even though the use of assisted reproductive technologies (ART) in aforementioned couples is increasing, their success rate is still relatively low.
- Conditions
- IVF, Body Weight, Nutrient Deficiency, Dietary Vitamin B12 Deficiency Anemia
- Trial name
- NCT05865015
- Where
- 2 sites in Slovenia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Endometriosis
Ovarian Blockade During Fertility Preservation in Patients With Endometriosis
The aim of the study is to demonstrate the non-inferiority of dienogest on the number of mature oocytes collected compared with "conventional" ovarian stimulation protocols (using a GnRH agonist or antagonist), in patients with…
- Trial name
- PFENDO (NCT06106919)
- Testing
- surveys (Fertiqol and WHOQOL-BREF)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
DSD, 46,XY, DSD, Ovotesticular
Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer).
- Conditions
- DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development
- Trial name
- DSD (NCT06692049)
- Testing
- Gonadectomy
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Erin Rowell
Stem Cell Transplantation
Survey of the Need for Information on Fertility and Menopause-Related Treatment Effects Among HSCT Patients
Primary Objective: To understand the importance of receiving information on fertility- and menopause-related treatment effects for female patients undergoing hematopoietic stem cell transplantation.
- Trial name
- NCT00429455
- Testing
- Survey
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- M.D. Anderson Cancer Center