Clinical trials: Female Genital Disease
Cervical Intraepithelial Neoplasia Grade 2/3, Adenocarcinoma in Situ
Effectiveness of Cervical Screening in Unvaccinated, Herd Effect Protected Women (HPV400)
To identify: 1) Whether being informed infrequently results about screening is at least as a) safe and b) accurate as frequently obtaining all information from (the present combination of opportunistic/organized) cervical…
- Trial name
- HPV400 (NCT04755517)
- Testing
- Frequent information of cytological/ HPV DNA screening results
- Where
- 18 sites in Finland
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Recurrent Ovarian Carcinoma
Helping Ovarian Cancer Patients Cope With Their Illness (HOPE)
This clinical trial compares the effect of the Helping Ovarian Cancer Patients Cope with Their Disease (HOPE) intervention to usual care for the reduction of hopelessness and helplessness in patients with ovarian cancer that has…
- Trial name
- NCT06666218
- Testing
- Behavioral Intervention, Electronic Health Record Review, Interview
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Fred Hutchinson Cancer Center
Ovarian Cancer, Testicular Germ Cell Tumor
Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002559
- Testing
- filgrastim, cisplatin, ifosfamide
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Epithelial Ovarian Cancer
Phase III Trial of Stage I Ovarian Cancer After Surgery
To compare the Overall survival of adjuvant chemotherapy versus observation in stage I epithelial ovarian cancer after comprehensive staging surgery
- Trial name
- NCT04063527
- Testing
- adjuvant chemotherapy
- Where
- 103 sites in Japan, South Korea
- Volunteers
- 360 people
- Sponsor
- Japanese Gynecologic Oncology Group
Endometrial Cancer
Physical Activity After Endometrial Cancer
Researchers propose to apply Social Cognitive Theory to improve understanding of the mechanisms of physical activity adherence for endometrial cancer survivors participating in a physical activity intervention.
- Trial name
- NCT00501761
- Testing
- Personalized Exercise Program, Questionnaire, Suggested Exercise Program
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Ovarian Cancer, Peritoneal Carcinomatosis
Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients
The purpose of this study is to determine if NIF fluorescent imaging is an effective approach to detect the gross ovarian tumoral tissues and peritoneal implants in Ovarian cancer patients.
- Trial name
- OV-AP-ICG-IV (NCT01834469)
- Testing
- iv injection of ICG
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Oncology, Endometrial Cancer
Patients Characteristics, Treatment Pattern & Outcomes of Patients With Advanced, Recurrent or Metastatic Endometrial Carcinoma
This is a national observational retrospective multi-site chart review study of patients with advanced, recurrent or metastatic endometrial carcinoma.
- Conditions
- Oncology, Endometrial Cancer, Advanced Cancer, Recurrent Cancer
- Trial name
- ENDOVIE (NCT05364905)
- Testing
- Chemotherapy
- Where
- 30 sites in France
- Volunteers
- 200 people
- Sponsor
- ARCAGY/ GINECO GROUP
Diabetes Mellitus, Non-Insulin-Dependent, Breast Cancer
Translating Healthy Lifestyle Interventions for Cancer Survivors
Investigators proposed to refine and test the feasibility and acceptability of a 4-month multi-modal lifestyle intervention in African American female breast or endometrial cancer survivors diagnosed with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Non-Insulin-Dependent, Breast Cancer, Endometrial Cancer
- Trial name
- NCT02690766
- Testing
- Standard Behavioral Weight Change Intervention
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ovarian Cancer, Colorectal Cancer
EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide
This study is looking at the safety and tolerability of the experimental biological drug EMD 273066 when given with low dose cyclophosphamide to patients with recurring EpCAM positive ovarian, prostate, colorectal or non-small…
- Conditions
- Ovarian Cancer, Colorectal Cancer, Carcinoma, Non-small-cell Lung, Prostate Cancer
- Trial name
- NCT00132522
- Testing
- EMD 273066
- Where
- 5 sites in United States, Switzerland
- Volunteers
- 45 people
- Sponsor
- EMD Serono
Ovarian Cancer, Fallopian Tube Cancer
Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study
This is a prospective preference study that will evaluate non-inferiority of the innovative treatment (RRS with delayed RRO) as compared to the standard treatment (RRSO) with respect to high grade serous (ovarian) cancer incidence
- Trial name
- NCT05287451
- Testing
- RIsk-Reducing Salpingectomy (RRS), Risk-Reducing Oophorectomy-RRO, Risk-Reducing Salpingo-Oophorectomy-RRSO
- Where
- 11 sites in United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Hypoactive Sexual Desire Disorder
Waitlist Controlled Comparison of Cognitive-behavioral vs. Mindfulness-based Online-treatments for Women With Low Sexual Desire
Problems with sexual function are common and distressing. The most frequent sexual difficulty in women is a lack of sexual desire with a prevalence of 20-30%.
- Trial name
- MiSELF (NCT03780751)
- Testing
- Cognitive-behavioral treatment, Mindfulness-based treatment
- Where
- Germany
- Volunteers
- 266 people
- Sponsor
- Ruhr University of Bochum
Amenorrhea, Endometriosis
Psychological Impact of Amenorrhea in Women With Endometriosis
The purpose of the study is to evaluate the impact on quality of life, psychological health, sexuality and chronic pain of therapies which determine amenorrhea in symptomatic women with endometriosis, through the administration…
- Conditions
- Amenorrhea, Endometriosis, Quality of Life
- Trial name
- NCT02393482
- Testing
- Estroprogestinic therapy (Etinil-estradiol/levonorgestre), Gonadotropin-releasing hormone agonist (Leuprorelin acetate), Add back therapy 1 (tibolone)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Cagliari
Partner Notification Following STI Diagnosis
Partner Notification Strategies for MSM in Peru
The goal of the proposed research is to assess new strategies for partner management and sexually transmitted infection (STI) control to reduce the spread of HIV-1 among men who have sex with men (MSM) in Latin America.
- Trial name
- NCT01720641
- Testing
- Internet, Referral Card, Internet and Referral Card
- Where
- Peru
- Volunteers
- 370 people
- Sponsor
- University of California, Los Angeles
Breast Cancer, Ovarian Cancer
Pilot Study Evaluating the Oncogramme: Analysis of Response to Induction Treatment of Patients With Breast or Ovarian Cancer.
The choice of treatments for cancers by systemic way - chemotherapy, hormone therapy and targeted therapies - is currently defined by criteria for population groups and not to an individual.
- Trial name
- ONCO S-O (NCT02910622)
- Testing
- Chimio-oncogramme
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Vaginal Discharge
Safety and Clinical and Microbiological Efficacy of the Combination of Fluconazole and Secnidazole for the Treatment of Symptomatic Vaginal Discharge
Genital tract infections (GTIs) have increased in the past decade and there is an association between sexually transmitted infections (STIs) and other infections like bacterial vaginosis (BV), with the HIV transmission.
- Trial name
- NCT02111629
- Testing
- Fluconazole and Secnidazole
- Where
- Colombia
- Volunteers
- 118 people
- Sponsor
- Universidad Nacional de Colombia
Endometrial Cancer
Treatment With Medroxyprogesterone Acetate Plus LNG-IUS in Young Women With Early Stage Endometrial Cancer
A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of Levonorgestrel-releasing intrauterine system (LNG-IUS) plus Medroxyprogesterone Acetate(MPA) in Young Women with Early Stage…
- Trial name
- NCT01594879
- Testing
- MIrena(LNG-IUS), oral MPA
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Korean Gynecologic Oncology Group
Endometriosis, Endometrioma
Optimum Menstrual Cycle Time for Endometrioma Excision
This study evaluates the optimum day of menstrual period for the excision of endometriomas to minimize the damage of surgery to normal ovarian tissue.
- Trial name
- NCT03484546
- Testing
- laparoscopic endometrioma cyst excision
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Cervical Cancer, Intraepithelial Neoplasia
Triage Strategies in Cervical Cancer Prevention
While there is broad consensus that HR-HPV detection is the best available primary screening test, there is no agreement about the most efficient and reliable triage procedure for HR-HPV positive women.
- Trial name
- FRIDA (NCT02510027)
- Testing
- HPV screening and triage tests
- Where
- Mexico
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Female Reproductive Problem, Infertility
Use of Corifolitropin Alfa in Oocyte Donors
The purpose of this study is to determine if corifollitropin alfa (long-term gonadotropin administration) is effective in a controlled ovarian stimulation protocol in oocyte donors compared to daily gonadotropin administration…
- Trial name
- NCT02213627
- Testing
- Corifollitropin alfa, Recombinant FSH, HP-hMG
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Cervical Cancer, Locally Advanced Cervical Cancer
Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC
It is a prospective, open-label, randomized, controlled phase II/III clinical trial in which patients with PD-L1-positive FIGO stage IB3, IIA2 and IIB（tumors >4 cm in diameter）will be enrolled and randomly divided into the…
- Conditions
- Cervical Cancer, Locally Advanced Cervical Cancer, Concurrent Chemoradiotherapy, Neoadjuvant Chemoimmunotherapy
- Trial name
- NCT06288373
- Testing
- Camrelizumab, Cisplatin, Nab paclitaxel
- Where
- 12 sites in China
- Volunteers
- 440 people
- Sponsor
- Tongji Hospital
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