Clinical trials: Femoral Head Necrosis
Degenerative Osteoarthritis, Rheumatic Arthritis
CoreHip - Post Market Clinical Follow-Up Study
The study is designed as a prospective, non-interventional multicentre cohort study. The product under Investigation will be used in Routine clinical practice and according to the authorized Instructions for Use (IfU).
- Conditions
- Degenerative Osteoarthritis, Rheumatic Arthritis, Fractures, Hip, Necrosis, Femur Head
- Trial name
- NCT03685110
- Testing
- CoreHip Total Hip Arthroplasty
- Where
- 6 sites in Germany, Switzerland
- Volunteers
- 248 people
- Sponsor
- Aesculap AG
Avascular Necrosis of the Femoral Head
Biologically Assisted Core Decompression of the Femoral Head Using the PerFuse Instrument and BioCUE
This study will evaluate the performance of biologically assisted core decompression with the PerFuse instrument and BioCUE in patients with bone lesions in the femoral head.
- Trial name
- REGP-44-00 (NCT02662881)
- Testing
- PerFuse Percutaneous Decompression System, BioCUE Platelet Concentration System
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Non Traumatic Osteonecrosis of the Femoral Head (Hip)
Safety, Tolerability, and Preliminary Efficacy of Intra-Articular Injection of Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Non-Traumatic Avascular Necrosis of the Femoral Head
This is a first-in-human, single-arm, open-label, dose-escalation, exploratory Phase I clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of local injection of mesenchymal stem cell-derived…
- Trial name
- NCT07787923
- Testing
- Exosome Intervention Group
- Volunteers
- 15 people
- Sponsor
- Beijing Jishuitan Hospital
Avascular Necrosis of Femoral Head
Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head
The purpose of this study is to test the effect of zoledronic acid over 2 years in preventing early collapse and progression of joint dome depression (≥ 2 mm by X-ray) of the femoral head in patients with large (> 30%: criteria…
- Trial name
- EZAPCOFH (NCT00939900)
- Testing
- zoledronic acid (aclasta)
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Arthritis
AMIStem Primary Hip System Prospective Post-marketing Multi-centre Surveillance Study
This is a multicentre post-marketing prospective study to evaluate performance and clinical outcomes of AMIIStem primary hip system.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT01107340
- Testing
- AMIStem Hip System
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 500 people
- Sponsor
- Medacta International SA
Osteoarthritis, Avascular Necrosis
Taperloc Complete Microplasty vs Taperloc Complete Standard: Randomized Controlled Study on Bone Mineral Density
The primary purpose of this study is to measure the postoperative changes in bone mineral density, comparing the Taperloc Complete Reduced Distal Microplasty stem and the standard length Taperloc Complete Reduced Distal stem.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- taperloc (NCT02087436)
- Testing
- Taperloc Complete Microplasty, Taperloc Complete Standard
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Avascular Necrosis of Femur, Bone Marrow
Autologous Bone Marrow Concentration for Avascular Necrosis of Femoral Head
This study aims to evaluate the effect of bone marrow concentration on avascular necrosis of femur head by comparing clinical and imaging outcomes between patients receiving core decompression surgery with intraoperative bone…
- Trial name
- NCT03787329
- Testing
- Core decompression surgery with bone marrow concentration, Core decompression surgery
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Pei-Yuan Lee, MD
Necrosis of Femoral Head, Knee Osteoarthritis
Ketamine Prevent POCD
Previous study demonstrated that neuroinflammation induced by surgery is the main cause of the postoperative cognitive dysfunction. As an agonist of NMDA receptor, ketamine is proved to be an anti-inflammation agent.
- Trial name
- KPPOCD (NCT02220400)
- Testing
- Ketamine
- Where
- 3 sites in China
- Volunteers
- 484 people
- Sponsor
- RenJi Hospital
Arthroplasty, Replacement, Hip
A Post Market Clinical Follow-up Study With the aneXys Cup
The purpose of the study is the evaluation of the clinical and radiological short- to long-term safety and performance of the aneXys cup. The data will be used for an ongoing evaluation of the product safety and performance.
- Trial name
- NCT03274830
- Testing
- aneXys
- Where
- 3 sites in Germany
- Volunteers
- 102 people
- Sponsor
- Mathys Ltd Bettlach
Osteolysis, Arthroplasty Complications
Plasmafit® Revision Structan® Hip Endoprosthesis Cup
The aim of this observational study is to collect clinical and radiological results of the new Plasmafit® Revision Structan® Hip Endoprosthesis Cup in a standard patient population and when used in routine clinical practice.
- Conditions
- Osteolysis, Arthroplasty Complications, Instability of Prosthetic Joint, Degenerative Osteoarthritis
- Trial name
- NCT04255966
- Testing
- Plasmafit® Revision Structan®
- Where
- 4 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Legg-Calve Perthes Disease
Intraarticular Corticosteroid Therapy in Perthes Disease.
Legg-Calve-Perthes disease (LCP) represents the loss of blood flow to the head of the femur, resulting in significant hip pain and potential long term disability.
- Trial name
- NCT01026909
- Testing
- Aristospan 20mg
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Seattle Children's Hospital
Osteoarthritis, Avascular Necrosis
Evaluate E1 Wear, Clinical Performance of E1 Liner in THA in Korean Patient Population
Evaluate E1 wear, Clinical Performance of E1 liner in THA in Korean Patient Population
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- E1Hip (NCT02087449)
- Testing
- E1-Hip Bearing
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.