Clinical trials: Femur Fracture
Femoral Neck Fractures, Periprosthetic Fractures
Postoperative Periprosthetic Fractures in Hip Fracture Patients: Exeter vs Anatomic SP2 Lubinus Stem
Recent studies have indicated a high incidence of postoperative periprosthetic femoral fracture in elderly patients treated with two commonly used cemented polished, tapered femoral stems.
- Trial name
- PPFEvL (NCT03326271)
- Testing
- Exeter stem, Lubinus SP2 stem
- Volunteers
- 2,527 people
- Sponsor
- Sundsvall Hospital
Femoral Fracture
Analgesia For Positioning Patient With Femur Fracture For Spinal Anaesthesia
This study is performed to determine the efficacy of ultrasound-guided fascia iliaca compartment block during positioning for spinal anaesthesia in patient undergoing repair of proximal femur fracture surgery comparing with…
- Trial name
- NCT02983344
- Testing
- Ropivacaine, Fentanyl, Ultrasound
- Where
- Malaysia
- Volunteers
- 24 people
- Sponsor
- Kuala Lumpur General Hospital
Femoral Neck Fractures
Vertical Femoral Neck Fractures in Young Adult Patients
Does the current techniques of internal fixation of vertical neck fracture in young adult patients give a satisfactory radiological and functional outcome at one year follow up?
- Trial name
- NCT04687592
- Testing
- reduction and fixation
- Volunteers
- 30 people
- Sponsor
- Assiut University
Blood Loss, Postoperative, Blood Loss, Surgical
EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDY
Perioperative blood loss is one of the most frequently encountered and significant complications of spine surgery. Intraoperative and post-operative bleeding cause various complications and negatively affect patient outcomes.
- Conditions
- Blood Loss, Postoperative, Blood Loss, Surgical, Femoral Fracture, Tibial Fracture
- Trial name
- NCT07625709
- Testing
- Intervention with Tranexamic Acid, Control group (Normal Saline)
- Where
- Nepal
- Volunteers
- 54 people
- Sponsor
- Kathmandu University School of Medical Sciences
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Hip Fractures (ICD-10 72.01-72.2)
Mobility and Activity of Daily Living Outcomes After a Hip Fracture.
Hip fractures in especially older adults cause severe clinical and functional impacts. Despite improved surgical care, one year mortality remains 14-30%, and fewer than half of the survivors regain their pre-fracture functional…
- Trial name
- MOVE-HIP (NCT07556263)
- Where
- Netherlands
- Volunteers
- 1,200 people
- Sponsor
- JointResearch
Hip Fractures, Stroke
Feasibility of the Geriatric Activation Program Pellenberg With Caregiver Involvement
This interventional study aims to see if involving caregivers as exercise partners with the physiotherapist throughout in-hospital geriatric rehabilitation and the first six weeks following discharge is feasible.
- Conditions
- Hip Fractures, Stroke, Frailty
- Trial name
- NCT05419284
- Testing
- GAPP+Care, +Care, Observation of GAPP+Care
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Direct Oral Anticoagulants (DOACs), Femoral Fractures
Impact of Treatment With Oral Anticoagulants of Patients With Fractures of the Upper End of the Femur
In 2023, oral anticoagulant treatments (anti Xa: apixaban , rivaroxaban, etc.) are tending to replace anti vitamin K treatments in many medical indications. Their prescription is increasing rapidly in the elderly.
- Conditions
- Direct Oral Anticoagulants (DOACs), Femoral Fractures, Surgery
- Trial name
- ANTI_XA AOD (NCT06382584)
- Testing
- Femoral fracture surgery
- Where
- France
- Volunteers
- 610 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Osteoporosis
Clinical Validation of BBCT-hip
The clinical study is aimed at assessing the accuracy of the in silico methodology BBCT-hip. BBCT-hip takes as inputs the subject-specific height and weight, and the CT scan of his femur to predict the risk of fracture for the…
- Trial name
- ValidaBBCT-hip (NCT06270758)
- Testing
- CT scan at the femur
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Fear of Other Medical Care
Kinesiophobia and Fear of Falling After Femur Fracture
This study will be conducted as intervention research to determine the effect of mobilization training to be provided to the patient undergoing hip arthroplasty on postoperative kinesiophobia and fear of falling.
- Trial name
- NCT06133608
- Testing
- MOBILIZATION TRAINING
- Volunteers
- 50 people
- Sponsor
- Kastamonu University
Hip Fractures, Quality of Life
Postoperative Intervention Educational Program on the Quality of Life of Patients With Hip Fracture
The objective of this study is to determine the impact of a postoperative educational intervention program on the health-related quality of life (HRQoL) of patients with hip fracture using a controlled clinical trial in a…
- Trial name
- NCT04650360
- Testing
- Postoperative Intervention Educational Program
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- University of Extremadura
Hip Fractures
The Safety of Anesthesia Management for Traumatic Hip Surgery in Elderly
Trauma for hip joint is common in old people. Anesthesia in these types of old patients carries more risk than the adult population.
- Trial name
- NCT02692989
- Testing
- Hip fracture surgery and anesthesia
- Where
- Jordan
- Volunteers
- 1,270 people
- Sponsor
- University of Jordan
Anesthesia, Hip Fracture Surgery
Efficacy of Perioperative Anesthesia Care Bundle on Prognosis in Elderly Undergoing Hip Fracture Surgery
This study is going to research the hypothesis that to strengthen the comprehensive treatment of perioperative anesthesia is possible to improve the prognosis of patients with hip fracture and reduce mortality.
- Conditions
- Anesthesia, Hip Fracture Surgery, Nursing
- Trial name
- EPAPHUS (NCT03429010)
- Testing
- New "guideline" anesthesia strategy team
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pelvic Fractures, Fragility Fractures of the Pelvis (FFP)
Assessment of Treatment Variability for Pelvic Ring Fragility Fractures
Fragility fractures of the pelvic ring are a common injury associated with poor patient outcomes and high healthcare costs. Management of these injuries is evolving with increasing frequency of operative stabilization of the…
- Trial name
- Pelvis ATV (NCT07351123)
- Testing
- Surgical stabilization of pelvic fracture, Closed treatment of pelvic fracture
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Maryland, Baltimore
Femoral Neck Fractures
Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty
This study is a double-blinded placebo-controlled clinical trial evaluating the efficacy of 1 gram of topically applied tranexamic acid vs. saline placebo for the reduction of transfusion following hip hemiarthroplasty surgery.
- Trial name
- NCT02664909
- Testing
- Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- UConn Health
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
Femoral Neck Fractures, Internal Fixation
Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation
This study is a prospective randomized controlled clinical study. Patients with femoral neck fracture (AO classification 31-B) will be randomly divided into three-screw fixation group and four-screw fixation group.
- Trial name
- NCT04869332
- Testing
- three cancellous screws, four cancellous screws
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Osteoporosis Risk, Fracture of Femur
Prediction Model of Hip Fragility Fracture Realistic Data From a Traumatology Department and Orthogeriatric Ward.
The aim of the project is to build a prediction model of hip fragility fracture using hospital data routinely collected in the traumatology department from the last 12 years and up to date Explainable Artificial Intelligence…
- Conditions
- Osteoporosis Risk, Fracture of Femur, Fragility
- Trial name
- NCT06545487
- Testing
- BLOOD SAMPLE
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Hip Fracture of Intertrochanteric Type, Thromboembolic Event
Diffrence in Thromboprofilaksis in Elderly Ostoepenic Hip Fractures According to Mobility Status by Genetic Analysis
Hip fracture is a common and severe disease in elderly patients. The question of the study is whether elderly patients with severe osteopenia have significantly lower levels of the collagen-binding protein Hsp47 than relatively…
- Conditions
- Hip Fracture of Intertrochanteric Type, Thromboembolic Event, Osteopenia, Thrombosis Embolism
- Trial name
- HSP 47 (NCT06959017)
- Testing
- Gene Expression Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Femoral Neck Fractures, Breathing Exercises
Effect of Liuzijue and Box Breathing on Inspiratory Capacity and Blood Pressure After Femoral Neck Fracture Immobilization
The purpose of this study is to understand how two simple breathing exercise techniques (Liuzijue and box breathing) affect inspiratory capacity and blood pressure in people who were immobilized after a femoral neck fracture.
- Conditions
- Femoral Neck Fractures, Breathing Exercises, Inspiratory Capacity, Blood Pressure
- Trial name
- NCT07389291
- Testing
- Liuzijue Qi Gong Exercise, Box Breathing Technique
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Saveetha University
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