Clinical trials: Femur Fractures
Stroke, Acute, Parkinson Disease
Assessment of the Rehabilitative Effects of Curved-walking Training in Stroke, Parkinson and Orthopaedic Populations
The recovery of walking ability is crucial to promote independence in daily living and is one of the major goal of neuromotor rehabilitation.
- Conditions
- Stroke, Acute, Parkinson Disease, Femur Fracture
- Trial name
- NCT03545477
- Testing
- Novel locomotion treatment: curved-walking training, Standard locomotion treatment: straight-walking training, Standard physical therapy
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Atypical Femur Fracture
Personalizing Osteoporosis Care: Clinical & Genetic Risk Factors for AFFs
The overall objective of this project is to identify clinical and genetic risk factors for Atypical Femur Fractures (AFFs) in Anti-resorptive therapy (ART) users by conducting a case control study of 330 cases of AFFs and 660…
- Trial name
- NCT04110795
- Testing
- No Intervention
- Where
- 3 sites in Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Bone Fracture, Tibia Fracture
Efficacy and Safety of SurgiFill™in Patients With Femur or Tibia Fracture
This study is designed to investigate the safety and efficacy of SurgiFill™, a bone grafting material, in patients with femur or tibia fracture.
- Conditions
- Bone Fracture, Tibia Fracture, Femur Fracture
- Trial name
- NCT07518836
- Testing
- femur or tibia fracture, SurgiFill™
- Where
- 3 sites in South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Hip Fractures, Knee Osteoarthritis
Effect of Remimazolam and Propofol on Postoperative Delirium
Remimazolam is an ultra-short acting benzodiazepine agonist which is used widely for general anesthesia and sedation. Remimazolam has several advantages.
- Conditions
- Hip Fractures, Knee Osteoarthritis, Femur Fracture
- Trial name
- NCT05514405
- Testing
- Remimazolam (Byfavo), Propofol
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inje University
Atypical Femur Fracture
Evaluation of IVA (SE Femur Scans) to Identify Incomplete AFFs
DXA scanners are routinely used to assess bone mineral density (BMD) and fracture risk in osteoporosis patients. They provide detailed bone imaging in a low radiation setting.
- Trial name
- NCT01747304
- Testing
- DXA Se femur scans (previously called IVA femur)
- Where
- Canada
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Osteoarthritis, Traumatic Arthritis
Actis Total Hip System 2 Year Follow-up
Two-year (2 year) information regarding the performance of the commercially available Actis™ Total Hip System in order to obtain and evaluate the clinical outcomes on a series of cementless primary total hip arthroplasty (THA)…
- Conditions
- Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Congenital Hip Dysplasia
- Trial name
- Actis14014 (NCT02783274)
- Testing
- Actis Total Hip System
- Where
- 9 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- DePuy Orthopaedics
Femur Fracture, Tibial Fractures
Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
The purpose of this trial is to determine whether oral acetaminophen and intravenous ketorolac are viable alternatives to opioid medication regimens for the pain management of patients with tibial and femoral shaft fractures…
- Trial name
- NCT04761302
- Testing
- Intravenous ketorolac and oral acetaminophen, Intravenous morphine and oral oxycodone
- Where
- Puerto Rico
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Distal Femur Fracture
Early Weight Bearing in Distal Femur Fractures
Assessment of the effect of double plating and single lateral plating on early weight bearing as a primary outcome and improving union and decreasing complications as secondary outcomes.
- Trial name
- NCT06806839
- Testing
- dual plating, single plating
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain, Femur Fracture
Comparing Suprainguinal Fascia Iliaca Block With Erector Spinae Plane Block in Hip and Proximal Femur Surgery
Most hip fractures occur in the elderly population. Opioid-related respiratory depression is more common in the elderly population but can cause severe brain damage or death.
- Conditions
- Postoperative Pain, Femur Fracture, Regional Anesthesia
- Trial name
- NCT05642975
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Marmara University
Osteoporosis Risk, Fracture of Femur
Prediction Model of Hip Fragility Fracture Realistic Data From a Traumatology Department and Orthogeriatric Ward.
The aim of the project is to build a prediction model of hip fragility fracture using hospital data routinely collected in the traumatology department from the last 12 years and up to date Explainable Artificial Intelligence…
- Conditions
- Osteoporosis Risk, Fracture of Femur, Fragility
- Trial name
- NCT06545487
- Testing
- BLOOD SAMPLE
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Femur Head Fracture, Arthroscopy
Is There a Role for Hip Arthroscopy in Patients With Femoral Head Fractures?
Femoral head fractures, often caused by high-energy trauma, pose significant challenges due to complications like avascular necrosis, post-traumatic osteoarthritis, and sciatic nerve damage.
- Trial name
- NCT06491420
- Testing
- fixation with arthroscopy
- Where
- Egypt
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Osteoporosis, With or Without Treatment, Bisphosphonate Treatment
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
Bisphosphonates are drugs that prevent bone loss by blocking the activity of cells that normally resorb bone. The most common examples of these drugs are Boniva and Fosamax.
- Conditions
- Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)
- Trial name
- NCT01875458
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hemorrhage, Fracture Femur
Comparative Use of Tranexamic Acid Intravenous and Topical Application in Intertrochanteric Fractures With PFNA
An intertrochanteric (ITF) trochanteric fracture of the femur is an exclusively extra capsular fracture in which the fracture line extends from the greater trochanter to the lesser trochanter.
- Trial name
- NCT04696224
- Testing
- Tranexamic acid, Saline solution
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Femur Intertrochanteric Fractures
Partial Weight Bearing Proximal Femoral Nail Due to Intertrochanteric Fracture.
Femur intertrochanteric fractures (FITC) are one of the most common fractures of the lower extremity, caused by osteoporosis, caused by minor trauma in elderly patients.
- Trial name
- randomized (NCT05602155)
- Testing
- Group 1, Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Closed Supracondylar Fracture of Femur
Immediate Weight Bearing Versus Protected Weight Bearing in Supracondylar Distal Femur Fractures
This study is designed to examine if immediate weight bearing on a distal femur fracture fixed with a primary locking plate, either a distal condylar locking plate or a LISS (less invasive stabilization system), is safe and…
- Trial name
- WtBrFemFx (NCT03167099)
- Testing
- Full Weight Bearing
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Femur Fracture
Effect of Preoperative Carbohydrate Loading in Femur Fracture
Femur fracture is very common in older people. It makes the people bedridden for long time at hospital. The fracture of femur is generally managed by the surgical procedure.
- Trial name
- NCT04838366
- Testing
- Carbohydrate loading
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Pertrochanteric Fracture of Femur, Closed
FEA, Biomechanical and Clinical Study of R.O. Peritrochanteric Fractures With PFLP vs Cephalomedullary Nail.
Hip fractures are the second most common fracture regardless of age, while at the same time its incidence is on the rise and it is expected to keep increasing in the future.
- Trial name
- NCT05286905
- Testing
- Osteosynthesis cephalomedullary nail, Osteosynthesis proximal femur locking plate
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Femur Neck Fracture, Arthroplasty Complications
Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
After total hip arthroplasty using an 'Modular Dual Mobility' acetabular cup, which is effective in reducing the risk of dislocation, one of the serious complications occurring after total hip arthroplasty, the blood metal ion…
- Trial name
- NCT05181566
- Testing
- Total hip replacement arthroplasty using modular dual mobility cup, Total hip replacement arthroplasty using conventional acetabular cup
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Fracture of Femur
Outcomes of Hemiarthroplasty Versus Cephalo-medullary Fixation to Treat Unstable Intertrochanteric Femoral Fractures
Comparing functional outcomes of hemiarthroplasty (prosthetic joint) versus cephalo-medullary fixation ( proximal femoral intramedullary nail) in the treatment of unstable intertrochanteric femoral fractures (proximal femur…
- Trial name
- NCT05134805
- Testing
- Bipolar hemiarthroplasty , proximal femoral nail
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University