Clinical trials: Femur Fractures, open to volunteers
Femoral Fracture, Fragility Fracture
Essential Amino Acid Supplementation for Femoral Fragility Fractures
This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture.
- Conditions
- Femoral Fracture, Fragility Fracture, Muscle Atrophy
- Trial name
- NCT06050668
- Testing
- Essential Amino Acid Supplementation
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Michael C Willey
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Proximal Humeral Fractures
Hip-allograft In Proximal Humerus Fractures Versus Plate Implantation Alone: a Randomized Controlled Trial
Proximal humerus fractures (PHFs) are common osteoporotic fractures in adults and the elderly, leading to significant disability and reduced quality of life.
- Trial name
- HIPPI (NCT07538700)
- Testing
- Locking plate fixation with femoral allograft augmentation
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Tergooi Medical Center
Fracture of Neck of Femur
Medial Enhancement Technique for the Treatment of Old Femoral Neck Fractures
A prospective, multi-center, randomized controlled study was conducted to validate the safety and effectiveness of employing the medial augmentation technique (incorporating the dynamic condylar screw and medial support plate)…
- Trial name
- NCT06713031
- Testing
- cannulated compression screws + iliac bone graft, DCS + medial support plate + iliac bone graft
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chinese PLA General Hospital
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Hip Fracture Surgeries
Comparative Study Between Pericapsular Nerve Group Block (PENG) And Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block for Positioning Analgesia Prior to Spinal Anesthesia in Hip Fracture Patients
To evaluate and compare the effectiveness of the Pericapsular Nerve Group (PENG) block alone versus the PENG block combined with the Lateral Femoral Cutaneous Nerve (LFCN) block in providing adequate analgesia for patient…
- Trial name
- NCT07687290
- Testing
- PENG Block, LCFN block, bupivacaine 0.25%.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Frailty, Hip Fracture
Frailty, Hip Fractures and Inflammatory Biomarkers
We ought to investigate if hip fracture patients suffering from frailty have higher inflammatory burden according to simple inflammatory biomarkers.
- Conditions
- Frailty, Hip Fracture, Inflammatory Biomarkers
- Trial name
- NCT06614478
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Hip Fracture, Perioperative Myocardial Injury
Nerve Block and Perioperative Myocardial Injury in Elderly Hip Fracture
This single-center, retrospective cohort study evaluates whether a single preoperative peripheral nerve block can reduce the risk of perioperative myocardial injury in elderly patients undergoing delayed hip fracture surgery…
- Conditions
- Hip Fracture, Perioperative Myocardial Injury, Myocardial Injury After Noncardiac Surgery
- Trial name
- PNB-CARD (NCT07751146)
- Testing
- PNB, Non-PNB
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Hip Fractures
Circum-Psoas Blocks Versus Combined Lumbar and Sacral Plexus Blocks in Hip Fracture Surgery
Hip fracture (HF) is one of the major worldwide problems that constitute a significant mortality rate, ranging from 14- 36% in the first year after injury, and is associated with profound temporary and sometimes permanent…
- Trial name
- NCT05660603
- Testing
- control, LSP, CP
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Osteoporosis, Osteoarthritis, Hip
Metabolic Profiling of Hematopoietic Stem Cells in Clonal Hematopoiesis (CHIP)
Bone marrow samples will be collected from patients undergoing hip arthroplasty surgery. Blood and bone marrow samples will be used for metabolic profiling and analysis of relevant CHIP mutations.
- Conditions
- Osteoporosis, Osteoarthritis, Hip, Hip Fractures, Clonal Hematopoiesis of Indeterminate Potential
- Trial name
- NCT05246813
- Testing
- Blood and bone marrow cell collection
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Imelda Hospital, Bonheiden
Articular Fractures
Geriatric Distal Femur
The goal of this clinical trial is to compare two types of surgical fixation in patients with specific kinds of distal femur fractures.
- Trial name
- NCT07237191
- Testing
- Single Implant Fixation, Dual Implant Fixation
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Wake Forest University Health Sciences
Femur Fracture
Effect of a Femoral Venting Hole on Embolic Load in Prophylactic Intramedullary Nailing
The purpose of this study is to measure intraoperative embolic burden during prophylactic intramedullary nailing of impending femur fractures in patients treated with versus without venting, to find the association between…
- Trial name
- NCT07778238
- Testing
- Femoral venting+ intramedullary nailing, Standard intramedullary nailing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Femur Neck Fracture, Hip Fractures
Lumbar Erector Spinae Plane Block Versus PENG Block for Hip Fracture Surgery
The purpose of this clinical trial is to compare two different nerve block techniques-the Pericapsular Nerve Group (PENG) block and the Lumbar Erector Spinae Plane Block (L-ESPB)-for managing pain after hip fracture surgery in…
- Conditions
- Femur Neck Fracture, Hip Fractures, Postoperative Pain
- Trial name
- NCT07910487
- Testing
- Pericapsular Nerve Group Block, Lumbar Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Beni-Suef University
Tourniquet Hypertension
A Long Axis Approach to the Femoral Artery Block (FAB) for Managing Tourniquet Pain and Hypertension in Below-the-Knee Fracture Surgery
This is a prospective, randomized, double-blind controlled trial evaluating an ultrasound-guided femoral artery block (FAB) using a long-axis in-plane approach compared with a short-axis approach and a control group.
- Trial name
- FAB (NCT07548567)
- Testing
- Femoral artery block - short-axis, Femoral artery block - long-axis, Normal saline injection (control)
- Where
- Greece
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Distal Femur Fractures
Single vs. Dual Implant Fixation for Distal Femur Fractures in Older or Compromised Adults
The goal of this clinical trial is to assess the feasibility of conducting a larger study comparing single implant fixation (SIF) and dual implant fixation (DIF) for treating distal femur fractures (DFF) in older or compromised…
- Trial name
- NCT06944964
- Testing
- Single Implant Fixation (SIF), Dual Implant Fixation (DIF)
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Articular Fractures
Single Versus Dual Implant Fixation of Distal Femur Fractures
The goal of this clinical trial is to compare two types of surgical fixation in patients with specific kinds of distal femur fractures.
- Trial name
- PRORP (NCT06286670)
- Testing
- Single Implant Fixation, Dual Implant Fixation
- Where
- 16 sites in United States
- Volunteers
- 144 people
- Sponsor
- Wake Forest University Health Sciences
Echocardiography, Hip Fractures
Preoperative Focused Cardiac Ultrasound in Hip Fracture Surgery (PrEcho)
The primary objective of this study is to investigate the impact of preoperative focused transthoracic ultrasound (FOCUS) on intraoperative hypotension and postoperative complications in hip fracture surgery.
- Conditions
- Echocardiography, Hip Fractures, Risk Assessment, Anesthesia
- Trial name
- PrEcho (NCT05862493)
- Testing
- FOCUS echocardiography
- Volunteers
- 100 people
- Sponsor
- Umeå University
Hip Fracture, Analgesia Post Fracture
PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture
Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture.
- Trial name
- NCT07046052
- Testing
- continuous infusion of levobupivacaine, Programmed Intermittent Bolus of Levobupivacaine
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- University College Cork
Dementia, Hip Fracture
Communication for Early Mobilisation of People Living With Dementia Following Surgery for Hip Fracture
This goal of this study is to identify ways that healthcare professionals communicate that are effective in helping a person living with dementia to stand or walk after surgery for a broken hip (hip fracture).
- Conditions
- Dementia, Hip Fracture, Early Mobilisation, Communication Research
- Trial name
- VOICE-HF (NCT07418268)
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
Delirium - Postoperative
Effects of PNB Timing on Postoperative Delirium for Hip Fracture
Hip fracture is a common cause of hospitalization in older adults and is associated with substantial pain and a high risk of delirium.
- Trial name
- NCT07856108
- Testing
- Peripheral Nerve Block for Hip Fracture
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's