Clinical trials: Fentanyl
Pain
Pharmacokinetic Study of Fentanyl 400 µg Sublingual Spray, Actiq® 400 µg Transmucosally, and Fentanyl Citrate Injection 100 µg Intravenously (iv)
The objective of this study was to compare the rate of absorption and bioavailability of fentanyl 400 µg sublingual spray, Actiq® 400 µg transmucosally, and fentanyl citrate injection 100 µg intravenously.
- Trial name
- NCT01780233
- Testing
- Fentanyl 400 µg sublingual spray, Actiq® 400 µg transmucosally, Fentanyl citrate injection 100 µg intravenously
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- INSYS Therapeutics Inc
Opioid Use, Unspecified
Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery
The purpose of this study is to determine if methadone improves postoperative pain control in pediatric patient's undergoing cardiac surgery.
- Trial name
- CV_RCT_M_F (NCT02747875)
- Testing
- Methadone, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Andrew Waberski
Pain, Acute
Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain
The objective of this study is to evaluate the potential opioid-sparing effect associated with the novel combination of fentanyl and sub-dissociative ketamine in adult patients with moderate to severe pain in the emergency…
- Trial name
- NCT03959852
- Testing
- Fentanyl, Fentanyl and Ketamine, Ketamine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Healthy
Study Evaluating Inhaled AeroLEF Delivered in 4 Aerosol Delivery Devices in Healthy Volunteers
This was an open-label, two-phase, crossover, safety, pharmacokinetic (PK), and pharmacodynamic (PD) study in normal, healthy, non-smoking, fasting male and female subjects. The first phase (A.
- Trial name
- LEF-07 (NCT00794209)
- Testing
- i.v fentanyl, AeroLEF
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- YM BioSciences
Analgesia
Depodur vs Fentanyl Infusion for Post-C/S Analgesia
Epidurally administered Depodur provides equal or superior analgesia as an epidural infusion of fentanyl for the first 48 hours after a cesarean section.
- Trial name
- NCT00762554
- Testing
- Depodur, Fentanyl
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
Dexmedetomidine VS Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics.
- Trial name
- NCT03463083
- Testing
- Dexmedetomidine, Bupivacaine, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor 2
Brief Summary: Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication…
- Trial name
- NCT02758405
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Analgesia
Confirmatory Study of HFVI Guided Analgesic Administration in Surgical Subjects
The current study is intended to be a prospective clinical performance validation study designed to confirm the clinical utility of HFVI-guided fentanyl administration during sevoflurane anesthesia.
- Trial name
- NCT04049656
- Testing
- HFVI
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Primigravida in Labour Pains
Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.
- Trial name
- NCT01205360
- Testing
- Bupivacaine-Fentanyl Mixture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Anesthesia
Propofol-fentanyl-ketamine (PFK) Combination Versus General Anesthesia Using Propofol and Fentanyl in Patients Undergoing Endoscopic Procedures.
Conscious sedation provides adequate control of pain and anxiety for the majority of routine endoscopic procedures as well as adequate amnesia.
- Trial name
- NCT04473846
- Testing
- PK general anesthesia, PFK combination
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Fentanyl Dependence
The Effects of Fentanyl Abuse on Executive Function and Related Brain Activity
There is a widespread abuse of prescription opioids and a dramatic increase in the availability of illicit opioids. These have created the "opioid epidemic" which is one of the most severe public health crisis in US History.
- Trial name
- NCT05469217
- Testing
- fMRI brain imaging
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ariel University
Abscess
Pain Management in ED for Incision and Drainage of Abscess
Patients presenting with painful procedures in the Emergency Department (ED) have been shown to frequently have inadequate pain management.
- Trial name
- NCT01881997
- Testing
- Fentanyl, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles