Clinical trials: Ferritin
IBD, Non Invasive Markers,IL6,Lactoferrin,Ferritin
The Validity of Novel Non-invasive Inflammatory Markers for Monitoring of Patients With Ulcerative Colitis
Ulcerative Colitis (UC) is a disease known for repeated relapses and remissions. So, meticulous follow-up is required to individualize treatment plans according to the status of each patient.
- Trial name
- NCT04670250
- Testing
- non invasive markers
- Volunteers
- 160 people
- Sponsor
- Assiut University
SARS-CoV-2 Infection
PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19
The purpose of this study is to evaluate the safety, reactogenicity, and immune response of the SpFN COVID-19 vaccine with Army Liposomal Formulation QS21 (ALFQ) adjuvant in healthy adults ages 18-55.
- Trial name
- NCT04784767
- Testing
- 25 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant), Sodium chloride, USP, for injection (0.9% NaCl), 50 µg SpFN_1B-06-PL + ALFQ (QS21 Adjuvant)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Fatigue, Iron-deficiency
Effect of Iron on Cerebral Dopamine Receptor Density in Non-anaemic Premenopausal Women With Low Ferritin and Fatigue
This study investigates the effect of intravenous iron substitution in non-anaemic premenopausal women with iron deficiency on: Changes in the cerebral Dopamine (DA) receptor density after iron substitution, shown by brain PET…
- Trial name
- NCT03305705
- Testing
- Iron Carboxymaltose, Sodium chloride 0.9%
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Albina Nowak, MD
Acute Myeloid Leukemia, Non-M3 Acute Myeloid Leukemia
Prognostic Value of CAR, AFR and Ferritin in Non-M3 AML
This prospective cohort study aims to evaluate the prognostic significance of the C-reactive protein-to-albumin ratio (CAR), albumin-to-fibrinogen ratio (AFR), and serum ferritin level in newly diagnosed de novo non-M3 acute…
- Conditions
- Acute Myeloid Leukemia, Non-M3 Acute Myeloid Leukemia, De Novo Acute Myeloid Leukemia With Multilineage Dysplasia
- Trial name
- NCT07810829
- Volunteers
- 208 people
- Sponsor
- Assiut University
Thrombocytosis, Iron-Deficiency Anemia
Ferinject® in Patient With Thrombocytosis Secondary to Inflammatory Bowel Disease (IBD)
The aim of this study is to show the benefits for patients, with a high platelet count, iron deficiency and IBD, receiving intravenous iron therapy.
- Trial name
- NCT00882414
- Testing
- FERINJECT® (Ferric carboxymaltose)
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Vifor Pharma
Anemia, Critical Illness
Hepcidine and Iron Deficiency in Critically Ill Patients
Anaemia is very frequent among critically ill patients, concerning more than 60 % of them at admission and more than 80% at intensive care unit discharge.
- Conditions
- Anemia, Critical Illness, Hospitalized for 5 Days or More
- Trial name
- HEPCIDANE (NCT02276690)
- Testing
- hepcidin, ferritin and transferrin saturation
- Where
- France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Montpellier
Postmenopausal Osteoporosis, Iron Metabolism Disorders
Association of Serum Ferritin and Bone Mineral Density With Bone Metabolism in Chinese Healthy Postmenopausal Women
Large amounts of experimental and animal evidence have confirmed that iron accumulation is associated with bone loss. However, it is still lack of the clinical studies relating iron accumulation to bone loss, especially in the…
- Trial name
- NCT03512743
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Pregnancy, Helicobacter Pylori Infection
Effects of Dietary Heme/Non-heme Iron and Helicobacter Pylori (Hp) Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Iron deficiency is considered one of the main nutritional deficiency disorders despite the apparent availability of a high-quality diet even in developed countries, and Iron deficiency anemia (IDA) is the most common form of…
- Conditions
- Pregnancy, Helicobacter Pylori Infection, Iron-Deficiency Anemia
- Trial name
- NCT01071759
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- E-DA Hospital
Still's Disease, Adult-Onset, Sepsis
Glycosylated Ferritin in Macrophagic Activation Syndromes
In healthy subjects, from 50 to 80 % of the serum ferritin is glycosylated [1, 2] . A decrease in the percentage of ferritin glycosylation can be observed in inflammatory diseases, malignancies, infections, or liver disease but…
- Conditions
- Still's Disease, Adult-Onset, Sepsis, Macrophagic Activation Syndrome
- Trial name
- FERRITGLY01 (NCT02143986)
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Brugmann University Hospital
Influenza
Influenza HA Ferritin Vaccine, Alone or in Prime-Boost Regimens With an Influenza DNA Vaccine in Healthy Adults
Background: Influenza, or "flu", is a very common infectious respiratory disease. Researchers want to develop a vaccine against flu. Vaccines teach the body to fight or prevent an infection.
- Trial name
- NCT03186781
- Testing
- VRC-FLUNPF081-00-VP (HA-F A/Sing), VRC-FLUDNA082-00-VP (DNA A/Sing)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Beta-thalassemia, Serum Ferritin
Efficacy and Safety of Efficacy and Safety of Continued Iron Chelation Therapy In Poly-transfused Thalassemia Patients With Low Serum Ferritin (< 500 ng/ml)
safety and efficacy of different iron chelation therapy in transfusion dependent beta-thalaasemia patients with low serum ferritin and continued regular transfusion regimen.
- Conditions
- Beta-thalassemia, Serum Ferritin, Iron Chelation Therapy
- Trial name
- NCT01996683
- Testing
- desferal, ferriprox, blood transfusion
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Myelodysplastic Syndrome, Iron Overload
Study of Deferasirox for Treatment of Transfusional Iron Overload in Myelodysplastic Patients
The purpose of this trial is to examine the safety and efficacy of deferasirox in patients with Myelodysplastic Syndrome (MDS) and chronic iron overload from blood transfusions.
- Trial name
- NCT00110266
- Testing
- Deferasirox
- Where
- 48 sites in United States, Canada
- Volunteers
- 176 people
- Sponsor
- Novartis Pharmaceuticals
MDS
Prognostic Value of Serum Erythropoietin Level,Ferritin Level and Fibrinogen in Adult Low Risk MDS
1. assessment of the penefit of erythropoietin administration in decreasing the frequency of blood transfusion in adult low risk MDS 2.
- Trial name
- NCT04573686
- Testing
- Erythropoietin
- Volunteers
- 50 people
- Sponsor
- Assiut University
Anemia, Iron-Deficiency, Kidney Failure, Chronic
DRIVE Trial (Dialysis Patients' Response to Intravenous [IV] Iron With Elevated Ferritin)
This study explores the safety and efficacy of intravenous iron therapy in anemic hemodialysis patients treated with epoetin alfa, who have higher serum ferritin levels, but low to normal transferrin saturation.
- Conditions
- Anemia, Iron-Deficiency, Kidney Failure, Chronic, Hemodialysis
- Trial name
- DRIVE (NCT00224081)
- Testing
- Sodium ferric gluconate,
- Where
- 29 sites in United States
- Volunteers
- 134 people
- Sponsor
- Watson Pharmaceuticals
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications
Cardiovascular disease is the leading cause of illness and death among individuals with type 2 diabetes mellitus (T2DM). Chronic low-grade inflammation contributes significantly to blood vessel damage, atherosclerosis, and…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure
- Trial name
- NCT07847112
- Volunteers
- 85 people
- Sponsor
- Assiut University
Anemia, Iron Deficiency
Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?
Globally, the most common cause of anemia is thought to be iron deficiency anemia (IDA). This was assumed to be the major cause of anemia in Cambodia, because Cambodian diets, which consist mainly of rice, lack iron-rich animal…
- Conditions
- Anemia, Iron Deficiency, Hemoglobin Disorder, Infection
- Trial name
- NCT02481375
- Testing
- Multiple micronutrients, Iron
- Where
- Cambodia
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Atherosclerosis, Intermittent Claudication
Does the Reduction of Total Body Iron Storage (TBIS) Alter Mortality in a Population of Patients With Advanced PVD?
Veterans Affairs Cooperative Study #410, The Iron and Atherosclerosis Trial, FeAST, a 24-hospital prospective randomized single-blinded clinical trial of graded iron reduction was conducted between May 1, 1999 and April 30, 2005…
- Conditions
- Atherosclerosis, Intermittent Claudication, Peripheral Vascular Diseases
- Trial name
- FeAST (NCT00032357)
- Testing
- Ferritin reduction to 25 ng/ml by phlebotomy
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 1,277 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Iron Deficiency
Iron Replacement in Blood Donors
Blood donors who have a low fingerstick hemoglobin level are usually deferred from donating. A possible solution to the problem of repeated deferrals might be for Blood Banks to offer donors with low hemoglobin levels oral iron…
- Trial name
- NCT00327067
- Where
- United States
- Volunteers
- 1,820 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
SAH, Dementia
Ferritin and Iron Burden in SAH sIRB
Ruptured cerebral aneurysms lead to subarachnoid hemorrhage (SAH),that has a high morbidity and mortality rate, the severity of which is predicted by the "Hunt-Hess grade" (HHG).
- Trial name
- NCT03754725
- Testing
- Deferiprone pill, Montreal Cognitive Assessment
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- Duke University
Serum Ferritin
Effects of Lactoferrin-enriched Whey on Iron Status in Females
The goal of this work is to study the effects of twice daily ingestion of a whey protein, rice protein, or maltodextrin drink enriched with lactoferrin- (200 mg), iron (6 mg) and vitamin B12 (5.2 µg) for 16-weeks on iron…
- Trial name
- NCT06232642
- Testing
- Lactoferrin, iron and B12 in Whey Protein, Lactoferrin, Iron and B12 in Rice Protein, Lactoferrin, Iron and B12 in Maltrodextrin
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Utah State University