Clinical trials: Fertility Disorders
Fertility
Exploring and Validating Biomarkers in Menstrual Blood
This study aims to find out whether menstrual blood can provide similar useful biological information to a standard blood sample taken from a vein in the arm as well as uterine biopsies and vaginal swabs.
- Trial name
- MB1 (NCT07638085)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genie Fertility Ltd
Abnormal Fertilization, Infertility
Outcomes of Embryos Created From Abnormally Fertilized Oocytes
The purpose of this study is to retrospectively analyze data from multiple clinics in a fertility network on embryos that were created from abnormally fertilized oocytes (AFO) including the rate of transfers and any clinical…
- Trial name
- NCT07666243
- Volunteers
- 92 people
- Sponsor
- Inception Fertility Research Institute, LLC
Fertility, Male Fertility
Sperm, Exposure and Endocrine Disruptors
The proposed research aims to 1) measure male participants' urinary levels of EDCs and sperm quality before and after report-back and EDC reduction intervention and assess changes, 2) assess the extent to which MM's program…
- Conditions
- Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
- Trial name
- SEED (NCT07703046)
- Testing
- EDC Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Million Marker Wellness, Inc.
Infertility, Female, Fertility Disorders
Comparison of Two PPOS Models for Pituitary Suppression
The scarcity of evidence regarding the interchangeable use of different progestogens poses challenges, particularly in international egg donation and fertility preservation programs where standardizing protocols is crucial for…
- Trial name
- NCT06304220
- Testing
- Cerazet
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- NextFertility
Infertility, Fertility
A Trial to Compare the Efficacy and Safety of Ovarian Stimulation With GONAL-f® and Luveris® Starting on Day 1 Versus Day 6 in Women Undergoing Assisted Reproductive Technique
This is a phase IIIb, interventional, multicenter, multinational, randomised, open-label, comparative trial which primary objective is to generate data on the ovarian stimulation profile obtained when Luveris® is started either…
- Conditions
- Infertility, Fertility, Follicle Stimulating Hormone Deficiency
- Trial name
- NCT01497197
- Testing
- GONAL-f®, Luveris®, Recombinant human chorionic gonadotropin (r-hCG)
- Where
- United Arab Emirates
- Volunteers
- 174 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Fertility Issues
DaVitri: Semi-Automated Vitrificacion Clinical Study
The main objective of this clinical study is to demonstrate the non-inferiority of the semi automated device (DaVitri) developed by Overture Life in the preparation procedures for vitrification of human samples.
- Trial name
- DaVitri (NCT05607771)
- Testing
- Manual Vitrification, Automated Vitrification
- Where
- 2 sites in Argentina
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Overture Life
Hypogonadism
Influence of Administration Route of Testosterone on Male Fertility
Exogenously administered testosterone will override the normal negative feedback of endogenous testosterone on the hypothalamus and pituitary.
- Trial name
- NCT00705796
- Testing
- MPP10, testosterone, Testosterone
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Acerus Pharmaceuticals Corporation
Male Infertility, Low Sperm Quality
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the…
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy
- Trial name
- NCT07740161
- Testing
- WeNatal For Him Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
Fertility Disorders
Evaluating the Usability of the Product Kinder System Trial, Home Based Hormone for In-Vitro Fertilization (IVF) Monitoring System.
In-vitro fertilisation (IVF) treatment involves women undergoing hormone stimulation (drug dosing) to produce more oocytes (eggs) to increase their chances of fertilisation.
- Trial name
- NCT05634850
- Testing
- Kinder
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- Planet Innovation
Fertility Disorders
ASA 81 mg vs 162 mg During Frozen Embryo Transfer (FET)
The use of low dose aspirin is recommended for high risk patients to reduce the risk of pre-eclampsia, placental abruption and antepartum hemorrhage.
- Trial name
- NCT06128395
- Testing
- Frozen embryo transfer
- Where
- Canada
- Volunteers
- 1,207 people
- Sponsor
- Clinique Ovo
Endometriosis
Pilot Study on a Dietary Supplement With EndoGen™ as Adjunct Therapy in Women With Endometriosis
Current treatments for endometriosis, such as NSAIDs and hormone therapies, are meant for long-term use but often cause side effects, including stomach, liver, heart, and kidney issues; allergies; and hormonal problems like…
- Trial name
- NCT07228975
- Testing
- MetrioFen Gocce
- Where
- 7 sites in Italy
- Volunteers
- 36 people
- Sponsor
- Endok s.r.l.
Fertility Disorders
Menopur And Rekovelle Combination Study
This study proposes to evaluate the effect of adding HP-hMG (Menopur) to follitropin delta in a "mixed protocol" regimen, using an individualized, fixed dose of follitropin delta based on the established algorithm, combined with…
- Trial name
- MARCS (NCT03483545)
- Testing
- Follitropin delta and HP-hMG
- Where
- 4 sites in Canada
- Volunteers
- 160 people
- Sponsor
- Dr François Bissonnette
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Healthy Elderly Volunteers, Mild-to-moderate Alzheimer's Disease Patients
A Two-part Multiple Dose Study to Assess the Safety and Effects of AZD3293 in Healthy Elderly and Alzheimer's Patients
This is a two-part multiple dose study in healthy male and female (of non-child bearing potential) elderly volunteers, and in Alzheimer's disease patients, to assess the safety, effects on the body, and blood, CSF, and urine drug…
- Trial name
- NCT01795339
- Testing
- AZD3293
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Multifollicular Stimulation
An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen
This is a prospective, observational and multicentric study to compare the Gonal-f FbM (filled by mass) dose prescribed by the doctor with the Gonal-f FbM dose determined by the CONSORT (Consistency in r-FSH Starting doses for…
- Trial name
- NCT01080729
- Testing
- Recombinant-follicle stimulating hormone (r-FSH)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
3 Year Retrospective Analysis of IVF in Comparison With INVOcell
Retrospective chart review of data on the use of traditional IVF and INVOcell IVC collected from clinics using both technologies. The retrospective data will be utilized for a comparison of the two methods.
- Trial name
- NCT05189405
- Testing
- INVOcell IVC
- Where
- 4 sites in United States
- Volunteers
- 450 people
- Sponsor
- INVO Bioscience, Inc.
Endometriosis, Adhesive
Prevention of Adhesions During Celioscopy for Endometriosis. Impact of the Use of Anti-adhesion Treatment on Clinical Signs and Fertility at One Year
Thus is a longitudinal, prospective, multicentric observational study performed in mainland France, among a sample of gynaecology surgeons practising at endometriosis "expert" centres.
- Trial name
- ENDHY (NCT02612818)
- Testing
- Coelioscopy
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Nordic Pharma SAS
Infertility
Impact of Follicular and Blood G-CSF During a Natural Cycle of IVF
Recently, scientists look into G-CSF (Granulocyte - Colony Stimulatin Factor). The use of this molecule is increasing in reproduction pathology.
- Trial name
- GCSFnat (NCT01668225)
- Testing
- Blood test
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- Clinique Ovo
Fertility, Infertility
New Strategies to Evaluate the Reproductive Tract Microbiome
The goal of this observational study is to evaluate alternative less invasive sampling methods for the analysis of the endometrial microbiome.
- Conditions
- Fertility, Infertility, Reproductive Health, Microbiome Analysis
- Trial name
- niMICROBIOME (NCT06920797)
- Testing
- Reproductive tract microbiome analysis
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Igenomix