Clinical trials: Fertility Disorders
HIV, Infertility
HIV and Ovarian Reserve
Recent evidence suggests a decline in fertility of persons living with HIV (PLWH) (delayed pregnancies, sponteanous abortions, especially when patients receive an antiretroviral therapy, early menopause, amenorrhea and…
- Trial name
- VIHRO (NCT03572270)
- Testing
- AMH test, pelvic ultrasound
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Ovarian Diseases, Ankylosing Spondylitis
Ovarian Reserve and Ankylosing Spondylitis
The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC).
- Conditions
- Ovarian Diseases, Ankylosing Spondylitis, Anti-Mullerian Hormone Deficiency
- Trial name
- NCT04209881
- Testing
- ovarian reserve for Ankylosing spondylitis and control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Aneuploidy, Pregnancy
The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
The goal of our research is to increase live birth rates in infertile women and to reduce the incidence of aneuploidy leading to miscarriage and trisomies.
- Conditions
- Aneuploidy, Pregnancy, Miscarriage
- Trial name
- CoQ10-IVF (NCT01048385)
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV Seropositivity, Pregnancy, High-Risk
Safer Conception Intervention for HIV-1 Serodiscordant Couples
The greatest burden of the HIV-1 epidemic lies in sub-Saharan Africa, where a substantial proportion of infections occur in long-term heterosexual HIV-1 serodiscordant partnerships.
- Trial name
- SCIP (NCT03030768)
- Testing
- PrEP, Counseling on timed condomless sex, ART and PrEP adherence
- Where
- 2 sites in United States, Kenya
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Washington
Breast Neoplasm Female
Developing a Web-based Shared Decision-making Tool for Fertility Preservation
The objective of this study was to develop a web-based, shared decision-making (SDM) tool for helping patients with breast cancer make decisions on fertility preservation.
- Trial name
- NCT04602910
- Testing
- a web-based shared decision-making tool
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome
Cohort Study to Evaluate Ovarian Function
The study will collect the clinical and biological data of the patients, the investigators could further analyse and identify the risk factors and optimize clinical treatment method.
- Conditions
- Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome, Sexual Function and Fertility Disorders, Cardiovascular Diseases
- Trial name
- NCT02294500
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shixuan Wang
Infertility, Fertility Issues
Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.
The goal of this study is to compare the difference in clinical pregnancy, miscarriage and livebirth rate between day 6 euploid blastocyst transfer on the 6th and the 7th day of progesterone exposure in Hormonal Replacement…
- Conditions
- Infertility, Fertility Issues, Infertility, Female
- Trial name
- NCT05980091
- Testing
- Transvaginal ultrasound, Serum LH, E2, P4, Estradiol Valerate 2 MG
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Uterine Fibroids, Infertility
a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy.
Premenopausal Women ages 18-42 will undergo a laparoscopic myomectomy. Prior to the myomectomy, adhesions will be assessed using a modified AFS scoring technique.
- Trial name
- VLocmyo (NCT01971060)
- Testing
- surgery utilizing V-Loc suture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Advanced Gynecologic Surgery Institute
Inguinal Hernia Bilateral
Inguinal Hernia Repair and Male Fertility
General objective: To evaluate the fertility of adult men submitted to bilateral herniorrhaphy with mesh placement by the Lichtenstein and laparoscopic approaches
- Trial name
- NCT05799742
- Testing
- Bilateral hernioplasty
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Life Style, Fertility Disorders
COaching Lifestyle Intervention for FErtility
In Finland, every third woman is overweight (BMI>25) and 11,5% obese (BMI>30). Cohort and national studies reveal that 46% of fertile-aged men have BMI≥25 and 20% BMI≥30.
- Trial name
- COLIFE (NCT04589793)
- Testing
- Life Style
- Volunteers
- 1,560 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Fertility Disorders, Ovarian Reserve Function
Fertility and Ovarian Reserve Function in the Patient With Inflammatory Bowel Disease
ECCO consensus, the fertility would decline in activity inflammatory bowel disease(IBD), because of anus lesions and pelvic abscess, or who underwent surgery, especially in patients with ileal pouch anal anastomosis (IPAA)…
- Conditions
- Fertility Disorders, Ovarian Reserve Function, Pregnancy Outcomes
- Trial name
- NCT03269916
- Testing
- Anti Mueller hormone, Estrogen, Follicle-Stimulating Hormone
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Educational Video
Fertility Awareness in University Students
Recent evidence showed that undergraduate students have inappropriate knowledge about reproductive health and infertility. The investigators' aim was to assess the effectiveness of a brief intervention (video) in increasing the…
- Trial name
- FAST (NCT02607761)
- Testing
- Video
- Where
- Portugal
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Fertility Disorders
Data Collection and Professional Simulated Use Study to Develop an Embryo Quality Artificial Intelligence (AI) Model
This protocol supports the reliable development and improvement of Artificial Intelligence (AI)-based applications by enabling training, verification, and validation using high-quality real clinical data.
- Trial name
- NCT07017972
- Testing
- AI evaluation of embryos
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fairtility
Infertility, Female, IVF
Fertility Supportive Behavior Education Based On Watson's Theory Of Human Care
Infertile individuals frequently attempt behavioral changes to enhance the effectiveness of their treatment and improve fertility outcomes.
- Trial name
- NCT06591637
- Testing
- Fertility supportive behavior education based on Watson's Theory of Human Care, Routine nursing care, The booklet "Fertility-Supporting Health Training
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Infertility, Assisted Reproductive Technology
Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes
This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization.
- Conditions
- Infertility, Assisted Reproductive Technology, Pregnancy Complications, Pregnancy Loss, Early
- Trial name
- Mi IVF (NCT07532629)
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Infertility
Histomorphometry Analysis in Fertile and Infertile Patients
To detect similarities and differences in the endometrium of fertile and infertile patients
- Trial name
- NCT01623063
- Testing
- Hysteroscopy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fertility Disorders
Quantum Natural Family Planning Pilot
•The Pilot study will involve current Marquette Method users who own and use a ClearBlue Fertility monitor and who will be asked to simultaneously use the Mira monitor for the sake of comparing the two devices to monitor the…
- Trial name
- QNFP (NCT03908697)
- Testing
- Mira monitor comparison to ClearBlue monitor
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Quanovate Tech Inc.
Infertility, Intrauterine Insemination (IUI)
The Level of Infertility Distress and Fertility Readiness of Women
The infertility treatment process is a multidisciplinary teamwork involving different professional groups. Especially the Controlled Ovarian Hyperstimulation (COH) protocols applied during the infertility treatment process…
- Trial name
- NCT06659497
- Testing
- web-based patient education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duzce University
Fertility Disorders
Effects of Lifestyle Changes on Semen Quality in Healthy Young Men Living in Highly Polluted Areas (FAST)
We planned a randomized controlled trial (RCT) with the main aim to evaluate the effects of lifestyle changes on semen quality in healthy young men living in polluted areas in Italy.
- Trial name
- FAST (NCT04012385)
- Testing
- lifestyle counseling
- Where
- 4 sites in Italy
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Salerno
Infertility, In Vitro Fertilization
Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
This study is a comparison between the current standard practice of performing a transvaginal oocyte retrieval (TVOR) with paracervical block (PCB) and a relatively recently developed technology of virtual reality that is added…
- Conditions
- Infertility, In Vitro Fertilization, IVF, ART
- Trial name
- NCT05438238
- Testing
- Oncomfort
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel