Clinical trials: Fetal Growth
Pregnancy Related, Remote Monitoring
Feasibility of Remote eCTG Monitoring Home@Hospital in Complicated Pregnancies
The objective of this single center, interventional cohort study is to evaluate the feasibility of remote electrophysiological cardiotocography (eCTG) monitoring in complicated pregnancies in a home@hospital setting.
- Conditions
- Pregnancy Related, Remote Monitoring, Feasibility
- Trial name
- HASTA (NCT06859177)
- Testing
- Remote eCTG
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Fetal Growth Abnormalities, Fetal Weight
Impact of AI Feedback on Ultrasound Biometry Accuracy Across the Expertise Levels
Objective: To evaluate the impact of real-time AI feedback on fetal biometry accuracy and investigate the Expertise Reversal Effect-whether AI benefits diminish as user experience increases.
- Trial name
- NCT07476638
- Testing
- AI interventional group
- Where
- 3 sites in Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Obstructive Sleep Apnea, Pregnancy
Auto-PAP Therapy For Improved Fetal Growth
The purpose of this study is to see whether the presence of night-time breathing disturbances ("sleep-disordered breathing") in pregnant women is related to fetal growth patterns.
- Trial name
- NCT03318003
- Testing
- Auto-PAP
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Pregnancy, Preeclampsia
The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR
The involvement of eukaryotic translation initiation factor 4E (eIF4E) in human placental implantation and in the pathological pregnancies: preeclampsia and IUGR.
- Trial name
- NCT01179542
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy
Effects of Prenatal DHA Supplements on Infant Development
This research study research is about the significance of polyunsaturated fatty acids (PUFAs) for human development. Specifically, the study team will assess the effect of docosahexanoic acid (DHA) supplementation during…
- Trial name
- NCT00646360
- Testing
- DHA
- Where
- Mexico
- Volunteers
- 1,094 people, healthy volunteers welcome
- Sponsor
- Emory University
Pregnancy Complications, Placental Insufficiency
PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome
The PREPPeD study proposes that predelivery placenta-derived maternal circulating biomarkers reflect placental health, capacity and ageing, and can help predict onset and complications of delivery both in complicated pregnancies…
- Trial name
- PREPPeD (NCT03100084)
- Testing
- Blood sampling
- Where
- Norway
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Fetal Growth Restriction, Placenta
Placental Progesterone Membrane Receptors in Fetal Growth Restriction
This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, among pregnancies affected by impaired fetal…
- Conditions
- Fetal Growth Restriction, Placenta, Progesterone Membrane Receptor, PGRMC1
- Trial name
- NCT07701837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samsun University
Stillbirth
Revealed Versus Concealed Cerebroplacental Ratio
The purpose of this study is to evaluate the role of an integrated strategy at selecting fetuses for delivery at term based on a combination of fetal biometry and cerebroplacental ratio (CPR) to reduce stillbirth rate and adverse…
- Trial name
- NCT02907242
- Testing
- Revealment
- Where
- 9 sites in Chile, Czechia and 4 more
- Volunteers
- 11,582 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Fetal Growth Restriction, Gut Microbiota
Gut Microbiota, SCFAs and Glucolipid Metabolism in Pregnant Women With Abnormal Fetal Size and Their Newborns
Abnormal fetal size includes fetal growth restriction and fetal macrosomia. Onset is closely related to maternal nutrition metabolism.
- Conditions
- Fetal Growth Restriction, Gut Microbiota, Fetal Macrosomia, Glucolipid Metabolism
- Trial name
- NCT04399434
- Testing
- test gut microbiota, SCFAs and glucolipid metabolism and insulin sensitivity
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Fetal Growth Retardation
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)
This study intends to prospectively enroll high-risk pregnant women to establish a multicenter cohort. By combining maternal basic characteristics, medical history, early pregnancy ultrasound, and biological markers, we aim to…
- Trial name
- NCT06096805
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Prenatal Care, Food Insecurity
Impact of Food Insecurity on Utilization of Maternal Healthcare Services and Birth Outcomes in Slums in Pune, India
The goal of this observational study is to assess household food insecurity among slum-dwelling women in India and to explore if household food insecurity is associated with utilization of maternal healthcare services, birth…
- Conditions
- Prenatal Care, Food Insecurity, Pregnancy Outcome
- Trial name
- MCH (NCT06313112)
- Testing
- Observational study
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Fetal Growth Retardation
Comparison of Pesticide and Pharmaceutical Contaminants Levels in Placenta and Cord Blood Samples of Pregnant Women With Fetal Growth Retardation and Healthy Pregnant Women
Aim: In this study, pesticide and pharmaceutical contaminants levels in the placenta and cord blood of pregnant women with fetal growth retardation and healthy pregnant women will be compared in placenta and cord blood samples…
- Trial name
- NCT05088148
- Testing
- . Pesticide and Pharmaceutical analysis
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Twin Pregnancy
Twins With Specific vs. Traditional Fetal Growth Charts
This study aims to compare how well two different types of fetal growth charts work in tracking the growth of twins during pregnancy. These charts help doctors decide if a fetus is growing normally.
- Trial name
- TWiST (NCT07164001)
- Testing
- Twin-Specific Growth Chart Interpretation, Singleton-Based Growth Chart Interpretation
- Volunteers
- 150 people
- Sponsor
- Indiana University
Fetal Growth Restriction
Evaluation of Fetal Heart
Evaluation of fetal cardiac functions in cases complicated with growth restriction
- Trial name
- NCT07760194
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Assiut University
Twin; Pregnancy, Affecting Fetus or Newborn, Fetal Growth Retardation
Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation
Optimal diagnostic management and underlying pathophysiological mechanisms of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin pregnancies have not been fully clarified.
- Conditions
- Twin; Pregnancy, Affecting Fetus or Newborn, Fetal Growth Retardation, Twin Monochorionic Diamniotic Placenta, Twin Diseases
- Trial name
- CONTRAST (NCT05952583)
- Testing
- Ultrasound
- Where
- 6 sites in United States, Belgium and 4 more
- Volunteers
- 274 people
- Sponsor
- Leiden University Medical Center
Fetal Growth Restriction (FGR)
AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study
The goal of this prospective cohort study is to enroll pregnancies complicated by placental-related fetal growth restriction (FGR) and to develop predictive models for adverse short- and long-term outcomes.
- Trial name
- NCT07473739
- Testing
- new ultrasound index and MRI
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fetal Growth Retardation, Stillbirth
Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress…
- Conditions
- Fetal Growth Retardation, Stillbirth, Neonatal Respiratory Failure, Neonatal Death
- Trial name
- NCT04640467
- Testing
- Biophsical profile, Cerebroplacental ratio
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Fetal Growth Retardation
EVERREST Developing a Therapy for Fetal Growth Restriction
Fetal Growth Restriction (FGR) is a major obstetric problem, affecting 1.46 million fetuses worldwide each year and contributing to 50% of stillbirths.
- Trial name
- EVERREST (NCT02097667)
- Where
- 4 sites in Germany, Spain and 2 more
- Volunteers
- 142 people
- Sponsor
- University College, London
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau