Clinical trials: Fetal Outcomes
Pregnancy, Eclampsia
A Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
In many low-income countries, the use of ultrasound by medical officers and non-physician health care staff (e.g., midwives) for antenatal identification of high risk pregnancies is a new intervention requiring authoritative…
- Conditions
- Pregnancy, Eclampsia, Placenta Previa, Stillbirth
- Trial name
- NCT01990625
- Testing
- Antenatal Ultrasound Scan
- Where
- 5 sites in Guatemala, Kenya and 3 more
- Volunteers
- 45,038 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Chronic Kidney Diseases, Pregnancy
Kynurenine Concentrations During Pregnancy in Women With or Without Chronic Kidney Disease - A Prospective Multicenter Study
Chronic kidney disease (CKD) affects more than 10% of the population worldwide and represents the second most important risk factor for preeclampsia, a life-threatening complication of pregnancy responsible for approximately…
- Conditions
- Chronic Kidney Diseases, Pregnancy, Preeclampsia
- Trial name
- KIDNEY-MOM (NCT07411937)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 204 people
- Sponsor
- CHU de Reims
Maturity-Onset Diabetes of the Young
Impact on Birth Weight of Two Therapeutic Strategies (Insulin Therapy From the Beginning of Pregnancy vs. Insulin Therapy Initiated According to Fetal Growth Evaluated by Ultrasonography Measurements) in Pregnant Women With Monogenic Diabetes
Maturity-onset diabetes of youth (MODY) are the most frequent monogenic diabetes with autosomic dominant inheritance (2% of diabetes).
- Trial name
- MODY2 (NCT02556840)
- Testing
- insulin therapy
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Perinatal Morbidity
General Anesthesia for Cesarean Section, Maternal and Perinatal Outcomes
To evaluate the maternal and perinatal outcomes that occur in obstetric patients undergoing cesarean section surgery under general anesthesia at the Fray Antonio Alcalde Civil Hospital of Guadalajara.
- Conditions
- Anesthesia, Perinatal Morbidity, Maternal-Fetal Relations
- Trial name
- NCT06160583
- Where
- Mexico
- Volunteers
- 5,000 people
- Sponsor
- Hospital Civil de Guadalajara
Pregnancy Complications
Prenatal Sonographic Prediction of Placental Histology and Function
The purpose of this two-phase observational study is to investigate the use of ultrasonography to predict placental pathology at the time of delivery.
- Trial name
- NCT06022458
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Covid19, Obstetric Complication
COVID-19 Infection and Fetal-neonatal Outcomes
COVID-19, the coronavirus responsible for the pandemic that began at the end of 2019 in China, spreads through respiratory droplets and direct contact.
- Conditions
- Covid19, Obstetric Complication, SARS-CoV Infection, Preterm Birth
- Trial name
- NCT04699578
- Testing
- Covid-19 positive
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- University of Campania Luigi Vanvitelli
Pregnancy; Disorder, Blood
Mineral Status in Pregnant Women
Ensuring an adequate supply of nutrients, which include trace elements, is particularly important in pregnancy. Both deficiency and excess of trace elements in the body can interfere with conception and maintaining a healthy…
- Trial name
- PREDISH (NCT03598361)
- Where
- Poland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Pregnancy
Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)
The goal of this clinical trial is to evaluate the potential benefit to patients and providers from using the remote fetal-monitoring system NUVO along with its app to allow for pregnant patients requiring weekly non-stress…
- Trial name
- SHOW-ME (NCT06741735)
- Testing
- INVU fetal monitoring system
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Missouri-Columbia
Insulin Resistance, Diabetes
Validation of a Novel Screening Test for Maternal Insulin Resistance
This will be a validation study of Quantose IR and Quantose IGT to predict insulin resistance and identify patients with prediabetes. This is a pilot study of 100 subjects.
- Trial name
- NCT03388697
- Testing
- Quantose IR and Quantose IGT analysis, HOMA IR the standard testing for insulin resistance
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Congenital Anomalies, Neonatal Complications
AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes
This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans.
- Conditions
- Congenital Anomalies, Neonatal Complications, Perinatal Outcomes, Perinatal Outcomes of the Mother and Fetus
- Trial name
- NCT07064356
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- FetalFirst Limited
Breastfeeding
PRenatal Video-Based Education and PostPARtum Effects
The purpose of this randomized controlled trial is to examine the impact of a remotely-delivered antenatal milk expression (AME) intervention versus an attention control condition on breastfeeding outcomes among a sample of 280…
- Trial name
- PREPARE (NCT04258709)
- Testing
- AME, Video-based infant care education
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Induction of Labor Affected Fetus / Newborn
Induction Of Labor: Predictors of Outcomes
Induction of labor is a widely used intervention in OBGYN practice. Doctors still use the old Bishop score in patients' follow up.
- Trial name
- IOL-ID (NCT04350437)
- Testing
- induction of labor
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Assiut University
Maternal Behavior, Alcohol Drinking
Adapting and Testing a Behavioural Intervention to Prevent FASD and Adverse Infant Outcomes
South Africa (SA) has a long history of social and health disparities, resulting in the world's highest rate of fetal alcohol spectrum disorder (FASD; 111.1 per 1,000), where lifelong negative cognitive and physical effects…
- Conditions
- Maternal Behavior, Alcohol Drinking, Fetal Conditions
- Trial name
- MaRISA+ (NCT05747599)
- Testing
- Intervention with contingent incentives and text-based support
- Where
- South Africa
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RTI International
Pregnancy
Effects of a Personalized Web-based Antenatal Care Planner
Many women are turning to the Internet to meet their health information needs, but the large amount of information available, as well as the unknown reliability and applicability of information can be overwhelming.
- Trial name
- NCT00182325
- Testing
- personalized web prenatal information, general web prenatal information
- Where
- Canada
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Laboring Women Requesting Neuraxial Labor Analgesia
Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes
The primary objective of this study is to compare the onset and duration of the initial dose of medications given through three different epidural (conventional epidural, combined spinal epidural and dural puncture epidural)…
- Trial name
- NCT02008591
- Testing
- Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brigham and Women's Hospital
Pregnancy
Perelel Prenatal Supplements vs. Generic Prenatal Supplements and Health of Mother and Baby (SUPPORT)
The goal of this clinical trial is to learn if using Perelel-brand prenatal supplements versus a generic prenatal supplement improves the health of the mother and fetus (unborn baby) during pregnancy.
- Trial name
- SUPPORT (NCT07046845)
- Testing
- Perelel Prenatal Vitamin, Generic Prenatal Vitamin
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Pittsburgh
Neurodevelopment
Nutrient Mixtures and Neurodevelopment
Background: Adequate levels of beneficial nutrients are important for neurodevelopment. Although, nutrients are ingested in combination, considering nutrients as a mixture has not been studied with respect to health, such as…
- Trial name
- NCT03420872
- Testing
- Nutrient mixtures
- Where
- Mexico
- Volunteers
- 329 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cesarean Section Complications
External Pop-out and Classic Fetal Head Extract During Cesarean Section
Cesarean section is the delivery of the fetus through a surgical incision in the abdominal wall (laparotomy) and uterine wall (hysterotomy).
- Trial name
- NCT03598764
- Testing
- Classic head extraction during Cesarean section, External pop out technique
- Where
- Egypt
- Volunteers
- 910 people
- Sponsor
- Assiut University
Congenital Heart Disease, Fetal Heart Disorder
Perinatal Cardiology: Bridging Obstetric and Neonatal Care in CHD
This prospective observational study aims to evaluate the agreement between prenatal fetal echocardiographic diagnoses and postnatal diagnoses of congenital heart disease, and to assess the impact of prenatal diagnosis status on…
- Conditions
- Congenital Heart Disease, Fetal Heart Disorder, Neonatal Disease, Fetal Disease
- Trial name
- NCT07820163
- Volunteers
- 115 people
- Sponsor
- Assiut University
Premature Birth, Neonatal Hypoglycemia
Higher-Dose Dexamethasone Improves Breathing and Shortens NICU Stay in Preterm Babies
The goal of this observational study was to compare two doses of dexamethasone given to pregnant women at risk of preterm birth. Dexamethasone is a medicine used before birth to help a baby's lungs mature.
- Conditions
- Premature Birth, Neonatal Hypoglycemia, Maternal Infection During Pregnancy, Neurodevelopmental Disorder of Foetus
- Trial name
- NCT07765329
- Testing
- Dexamethasone 12 mg Every 12 Hours, Dexamethasone 6 mg Every 12 Hours
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Stella Maris Women and Children Hospital