Clinical trials: Fetal Structural Anomalies
Pregnancy Related
Diagnostic Performance of Antenatal Ultrasound for High-Risk Intestinal Malrotation
The aims of this study are: To assess the performance of third-trimester ultrasound scan in the localization of intestinal structures (small bowel, gut, mesenteric vessels..) involved in malrotations with a higher-risk of…
- Trial name
- MALGRE (NCT03968107)
- Testing
- Reference ultrasound examination
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Speckle Tracking, Fetus Fetus
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using pulsed wave Doppler, Tissue Doppler and speckle tracking (strain and strain rate) between foetuses/neonates with a structural heart disease…
- Conditions
- Speckle Tracking, Fetus Fetus, Neonate, Structural Heart Disease
- Trial name
- STIPP (NCT05601375)
- Testing
- Echocardiography
- Where
- Netherlands
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Fetal Structural Anomalies
Genomic Sequencing for Evaluation of Fetal Structural Anomalies
This study follows an observational prospective cohort design. Women with fetal structural anomalies are routinely offered diagnostic testing with chorionic villus sampling or amniocentesis, with analysis for chromosomal analysis…
- Trial name
- NCT06054230
- Testing
- Genomic Sequencer
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intrauterine Growth Restriction, Fetal Anomaly
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies
The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or…
- Conditions
- Intrauterine Growth Restriction, Fetal Anomaly, Chromosomal Anomalies, Pregnancy
- Trial name
- NCT03398629
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Fetal Structural Anomalies
Prenatal Genetic Diagnosis by Genomic Sequencing
This study is evaluating the impact of prenatal sequencing on the management of fetuses with ultrasound abnormalities. The hypothesis is that a significant subset of fetal abnormalities have a genetic cause that can be identified…
- Trial name
- PrenatalSEQ (NCT03936101)
- Testing
- Prenatal Genomic Sequencing
- Where
- 5 sites in United States
- Volunteers
- 1,097 people, healthy volunteers welcome
- Sponsor
- Columbia University
Structural Anomalies, Cardiac Anomalies
Clinical Utility of Prenatal Whole Exome Sequencing
The investigator aims to examine the clinical utility of WES, including assessment of a variety of health-related and reproductive outcomes in undiagnosed prenatal cases.
- Conditions
- Structural Anomalies, Cardiac Anomalies, Central Nervous System Anomalies, Thorax Anomalies
- Trial name
- PWES (NCT03482141)
- Testing
- Whole Exome Sequencing (WES)
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- University of California, San Francisco
Heart Diseases
Development of an Screening System in Children With Congenital Heart Disease Based on Cloud Computing and Big Data
This study intends to establish an automatic system for screening on children with congenital heart disease, the system include the auscultation of cardiac murmur and the test of oxygen saturation, the data was analyzed based on…
- Trial name
- NCT03929133
- Testing
- automatic screening machine on congenital heart disease
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fetal Growth Retardation, Fetal Neurodevelopmental Disorder
Evaluation of Anterior Middle Brain Structures With Cerebrovascular Flow in Fetuses With Fetal Growth Restriction
The study will be conducted to examine the effects of abnormal growth pattern and cerebrovascular blood flow measurements on fetal frontal lobe development with the advancing ultrasound technology.
- Trial name
- NCT06215690
- Testing
- Ultrasound measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital