Clinical trials: Fetus Fetus
Delivery Complication, Delivery Problem
Delivery Outcomes by AIDA (Artificial Intelligence Dystocia Algorithm) Analysis
Aims: Primary aim is to investigate outcomes of eutocic labor, evaluating intrapartum ultrasound parameters by AIDA method: Angle of progression (AoP), Asynclitism degree (AD), fetal head-symphysis distance (HSD), and midline…
- Conditions
- Delivery Complication, Delivery Problem, Delivery; Injury, Delivery; Injury, Maternal
- Trial name
- AIDA (NCT06664112)
- Testing
- AIDA Analysis
- Where
- 2 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Vacuum Extraction; Failure, Affecting Fetus or Newborn, Persistent Occiput Posterior Position During Labor
R. I. S. POS. T. A
A failed operative vaginal delivery is associated with increased risk of maternal and perinatal complications. It is very important the determination of the fetal head position prior to instrumental delivery.
- Conditions
- Vacuum Extraction; Failure, Affecting Fetus or Newborn, Persistent Occiput Posterior Position During Labor, Complication of Delivery
- Trial name
- RISPOSTA (NCT01991665)
- Testing
- Digital examination, Sonography evaluation
- Where
- Italy
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Missed Abortion, Medical; Abortion, Fetus
Gemeprost Versus Dinoprostone in First Trimester Miscarriages
Comparison between gemeprost and dinoprostone to evacuate first trimester miscarriages.
- Conditions
- Missed Abortion, Medical; Abortion, Fetus, Incomplete Abortion
- Trial name
- NCT05342467
- Testing
- Gemeprost 1 Mg Vaginal Pessary, Dinoprostone 3 mg
- Where
- 2 sites in Malaysia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Drug; Withdrawal Symptoms, Neonatal, Withdrawal
Sublingual Buprenorphine Treatment for Neonatal Abstinence Syndrome - Pilot Study
Summary: There have been two published RCTs showing efficacy of buprenorphine treatment for NAS. However these trials excluded an estimated 22-47% of infants requiring pharmacologic treatment; those infants born to mothers with…
- Conditions
- Drug; Withdrawal Symptoms, Neonatal, Withdrawal, Fetus and Newborn Affected by Other Maternal Medication
- Trial name
- NCT02249026
- Testing
- BZDs + opiate exposure treated with BPN, Opiates exposure treated with BPN
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gauda, Estelle B., M.D.
Pregnancy Related, Mother-Child Relations
The Effect of Pregnant Women's Maneuvers on Pregnancy Distress and Perception of Maternity Role"
The role of motherhood; Motherhood can be defined as a learning process that includes knowledge, skills, attitudes and behaviors of a woman who has been handed down from generation to generation.
- Trial name
- NCT05962866
- Testing
- I and II. Performing Leopold Maneuvers by the pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sibel ÖZTÜRK
Congenital Heart Disease, Disorder of Fetus or Newborn
Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Randomized controlled trial of the use of glucocorticoids to improve the clinical course of neonates post-cardiopulmonary bypass (CPB).
- Trial name
- NCT00934843
- Testing
- methylprednisolone (IVMP), methylprednisolone (two doses IVMP)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Medical University of South Carolina
Chorioamnionitis Affecting Fetus or Newborn, Amnioinfusion
Amnioinfusion for Chorioamnionitis: Targeting Neonatal Brain Injury Biomarkers
The AMNIO-BRAIN Trial is a research study looking at whether a simple treatment during labor can help protect a baby's brain. Some newborns develop a condition called hypoxic-ischemic encephalopathy (HIE), which happens when the…
- Conditions
- Chorioamnionitis Affecting Fetus or Newborn, Amnioinfusion, Neonatal Brain Injury
- Trial name
- AMNIO-BRAIN (NCT07610642)
- Testing
- Intrauterine Pressure Catheter, Standard obstetric care at discretion of delivery provider
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical College of Wisconsin
Pregnancy, Labor; Forced or Induced, Affecting Fetus or Newborn
Outpatient Labor Induction With the Transcervical Foley Balloon
This study represents the first randomized trial comparing traditional inpatient induction with a transcervical foley catheter versus outpatient induction with immediate removal of a transcervical foley catheter.
- Trial name
- NCT02210598
- Testing
- inpatient Foley balloon induction, outpatient Foley balloon induction, Oxytocin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Southern California
Induction of Labor Affected Fetus / Newborn
Cervical Ripening With a Double-lumen Balloon Catheter for Six Versus Twelve Hours
The Foley catheter is a safe, effective method for cervical ripening. Limited data exists to indicate ideal time of placement for optimal cervical ripening prior to induction.
- Trial name
- NCT03086967
- Testing
- Double-lumen balloon catheter
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Wake Forest University Health Sciences
Mental Disorder, Fetus Disorder
Diagnosis of Prader-Willi Syndrome and Angelman Syndrome
In a retrospective study, data were assessed from cases regarding PWS/AS that underwent molecular diagnosis at the National Chen-Kung University Hospital, Tainan, Taiwan, between January 2001 and December 2014.
- Trial name
- NCT04155944
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Fetal Growth Retardation, Induction of Labor Affected Fetus / Newborn
Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes
to compare methods of induction of labor in fetal growth restriction and its effect on maternal and neonatal outcome
- Trial name
- NCT03625518
- Testing
- prostaglandins E2, intracervical balloon catheter combined with pitocin
- Where
- Israel
- Volunteers
- 280 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Induction of Labor Affected Fetus / Newborn
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity increases the risk of pregnancy complications, including among others puerperal infections and cesarean delivery, and risk rises with increasing body mass index (BMI).
- Trial name
- APPOINT (NCT03801252)
- Testing
- Cefazolin, Azithromycin
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Fetal Cardiac Disorder
Fetal Cardiac Function Evaluation With aCMQ-Strain Fetal (STRAIN)
To assess whether the aCQM-Strain ultrasound method allows a good analysis of fetal cardiac function. Establish normality parameters and compare it with fetuses with risk factors of cardiac dysfunction.
- Trial name
- STRAIN (NCT03536000)
- Testing
- Fetal echocardiography using the aCMQ-Strain method
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Neonatal Abstinence Syndrome
Physiology and Therapeutic Management of Neonatal Abstinence Syndrome
The overall purpose of this project is to to quantify the physiology of neonatal drug withdrawal and develop non-pharmacological techniques to help improve the therapeutic management of Neonatal Abstinence Syndrome (NAS).
- Trial name
- NCT02768844
- Testing
- Stochastic Vibrotactile Stimulation (SVS), Control
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Massachusetts, Worcester
Medical Induction of Labor Affecting Fetus
Effect Of Intra-muscular Administration of Dexamethasone in Induction of Labour
ABSTRACT: Objective: To evaluate the efficacy of dexamethasone on labor duration and to establish whether dexamethasone plays a role in shorting the duration interval between initiation of labor induction and beginning of the…
- Trial name
- NCT02508402
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Dystocia; Fetal, Labor Long
Mouth Guard Use in the Second Stage of Labor
Shortening the second stage of labor, the time spent pushing the baby out, is important for positive mother and infant's outcomes.
- Conditions
- Dystocia; Fetal, Labor Long, Cesarean Section, Affecting Fetus or Newborn
- Trial name
- NCT03520530
- Testing
- Mouth Guard
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Assessment of Fetal Movement, Pregnancy
Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements
The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care.
- Conditions
- Assessment of Fetal Movement, Pregnancy, Pregnancy Complications, Pregnancy Complications Affecting Fetus (Diagnosis)
- Trial name
- WWA (NCT07626112)
- Testing
- Smartphone Application
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kenneth Moise MD
Fetal Growth Retardation
Fetal Heart Rate Variability and Fetal Growth Restriction
There is growing evidence in the field of fetal heart rate variability revealing the fetal neurological state. Furthermore, fetal heart rate variability has shown potential as fetal surveillance in fetal growth restriction.
- Trial name
- (FGR) (NCT04288037)
- Testing
- fetal heart rate variability
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Friedreich Ataxia
A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies
In this study, researchers will learn more about the safety of BIIB141, also known as omaveloxolone or SKYCLARYS. This is a drug available for doctors to prescribe for people with Friedrich's Ataxia, also known as FA.
- Trial name
- NCT06628687
- Testing
- Omaveloxolone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Biogen
Prevention of Vitamin Deficiency During and/or Before Pregnancy
A Study to Gather Information About the Progress and Outcomes of Pregnancy in Women Using Various Vitamin Support Plans Before and During Pregnancy
This is an observational study in which data from the participants who will be taking different vitamin supplementation regimes before and during pregnancy.
- Trial name
- NCT05062044
- Testing
- Multivitamins (Elevit, BAY987808), Multivitamins (Elevit, BAY2906300), Multivitamins (Elevit, BAY987386)
- Where
- 3 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bayer