Clinical trials: Fibrin Blood Clot
Revascularization of Immature Permenant Teeth
Revascularization of Immature Teeth With Our Different Scaffolds
the study concern with the patients who loss the vitality of their teeth before completion of root development and apply new treatment approaches to restore their vitality through different scaffolds applied in inside the root…
- Trial name
- NCT07913880
- Testing
- Blood Clot, Platelet Rich Plasma, Platelet Rich Fibrin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Pulmonary Embolism (PE), Deep Vein Thrombosis (DVT)
Evaluation of Soluble Fibrin in Thrombosis Exclusion
The purpose of the study is to evaluate the performances of Soluble Fibrin assay for exclusion of Pulmonary Embolism and Deep Venous Thrombosis.
- Trial name
- FSET (NCT02523937)
- Testing
- Soluble Fibrin
- Where
- France
- Volunteers
- 863 people
- Sponsor
- Diagnostica Stago R&D
ST Elevation Myocardial Infarction
Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction
GNR-060(JSC "GENERIUM", Russia) is a proposed biosimilar to the referent product Metalyse. This study is to compare the clinical efficacy and safety of GNR-060 vs Metalyse as a thrombolitic agent in patients with with ST…
- Trial name
- NCT05601999
- Testing
- GNR-060, Metalyse
- Where
- 11 sites in Russia
- Volunteers
- 244 people
- Sponsor
- AO GENERIUM
Pulmonary Embolism (PE)
Soluble Fibrin for Diagnosing Pulmonary Embolism
The purpose of the study is to evaluate the performances of Soluble Fibrin for diagnosing Pulmonary Embolism. Secondary objective is to compare the diagnostic performances of the Soluble Fibrin Assay and the D-Dimer test.
- Trial name
- SOFIE (NCT02438462)
- Testing
- Soluble Fibrin
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Diagnostica Stago R&D
Rotator Cuff Tear
Vascular Changes of Rotator Cuff Repair Augmented With a Whole Blood Fibrin Clot
The goal of this study is to assess whether undergoing surgical repair of the rotator cuff with the additional intervention of whole blood fibrin clot will improve rotator cuff vascularization at the bone-tendon interface repair…
- Trial name
- NCT03577379
- Testing
- Whole Blood Fibrin Clot
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Santa Barbara Cottage Hospital
Periodontoclasia, Gingiva; Injury
Use of Injectable-platelet-rich-fibrin (I-PRF) to Thicken Gingival Phenotype
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival…
- Conditions
- Periodontoclasia, Gingiva; Injury, Condition, Blood Clot
- Trial name
- NCT03274674
- Testing
- I-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Regenerative Endodontics
Clinical and Radiographic Outcomes of PRF, Chitosan, and Blood Clot in Regenerative Endodontics of Molars
This clinical trial aimed to evaluate the long-term effects of using chitosan, blood clots, and platelet-rich fibrin as scaffolds in regenerative endodontics on tooth development.
- Trial name
- NCT07119619
- Testing
- Regenerative Endodontic Treatment Using a Blood Clot as a Scaffold, Regenerative Endodontic Treatment Using a Chitosan as a Scaffold, Regenerative Endodontic Treatment Using a Platelet Rich Fibrin as a Scaffold
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Inonu University
Malignant Tumor
Evaluation of Fibrin Structure Marker in Cancer Patients Treated and Not Treated With LMWH
The purpose of the study is to assess the fibrin structure marker in the plasma of cancer patients, treated or not treated with LMWH at prophylactic or therapeutic doses, in order to determine the venous thromboembolic risk.
- Trial name
- FICT (NCT02552381)
- Testing
- Fibrin Structure
- Where
- France
- Volunteers
- 389 people
- Sponsor
- Diagnostica Stago R&D
Hemophilia a
EVALUATION of the OVERALL HAEMOSTATIC CAPACITY of MIM8 with GLOBAL HAEMOSTASIS ASSAYS and FIBRIN CLOT ULTRASTRUCTURE
Hemophilia A is an X linked disorder characterized by a deficiency in Factor VIII. The clinical hallmark of this disease is increased tendency to spontaneous bleeding with hemarthrosis accounting for 90% of the hemorrhages.
- Trial name
- Mim8-TGT (NCT06212505)
- Testing
- blood test
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Disease, Reperfusion Injury
Intra-graft Coagulation Events in Clinical Renal Transplantation and Delayed Graft Function
The purpose of this study is to investigate local activation of the coagulation system in the kidney graft during organ preservation and during early reperfusion in adult kidney transplantation.
- Conditions
- End Stage Renal Disease, Reperfusion Injury, Delayed Graft Function, Kidney Transplantation
- Trial name
- KTX (NCT02568696)
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Deep Vein Thrombosis
Clinical Trial to Evaluate the Accuracy of [99mTc] ThromboView in the Detection of Deep Vein Thrombosis
The assessment of patients with suspected deep vein thrombosis (DVT) is a common clinical scenario that, despite major advances in diagnostic testing, continues to be challenging.
- Trial name
- NCT00123734
- Testing
- ThromboView
- Where
- 12 sites in United States, Canada
- Volunteers
- 94 people
- Sponsor
- Agen Biomedical
Meniscus Tear, Meniscus Lesion
Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears
Longitudinal meniscal tears are a type of meniscal injury characterized by a displaced fragment of the meniscus that flips over into the joint, often resembling a buckle or handle.
- Conditions
- Meniscus Tear, Meniscus Lesion, Fibrin Blood Clot, Knee Injuries
- Trial name
- FCAR (NCT06541756)
- Testing
- Fibrine Clot-augmented Meniscal Repair, Conventional Meniscal Repair
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Pulp Necrosis, Immature Permanent Teeth
PRF and CGF Scaffolds With EDTA in Regeneration
This study evaluated the regenerative outcomes of immature permanent teeth with necrotic pulps treated using three scaffold types-blood clot, platelet-rich fibrin (PRF), and concentrated growth factor (CGF)-combined with either…
- Conditions
- Pulp Necrosis, Immature Permanent Teeth, Open Apex, Periapical Periodontitis
- Trial name
- RET-EDTA-CGF (NCT07265804)
- Testing
- Blood Clot + 5% EDTA, Blood Clot + 17% EDTA, PRF + 5% EDTA
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Pulmonary Embolism, Deep Vein Thrombosis
PET Fibrin Imaging of DVT and PE
This study aims to investigate a novel positron emission tomography(PET)-probe for imaging of fresh intravascular blood clots in pulmonary embolism (PE) and deep venous thrombosis (DVT).
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT04022915
- Testing
- 64Cu-FBP8, PET-CT imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Peter Caravan
Fibrin Blood Clot, Infertility, Female
Ovarian Hyperstimulation and Fibrin Clot Properties.
The impact evaluation of ovarian hyperstimulation on coagulation and fibrinolysis in infertile women. Comparative analysis between different ovarian stimulation protocols on thrombin formation and efficiency of fibrinolysis in…
- Conditions
- Fibrin Blood Clot, Infertility, Female, Endometriosis
- Trial name
- NCT04166825
- Testing
- fibrin clot properties
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Blood Platelet Transfusion, Blood Clotting
Study to Reveal if Fibrinogen Treatment Effects Blood Clotting Better Than a Platelet Transfusion
Patients with need of platelet transfusion for any reason will participate in this study. Directly before the start of infusion and one hour after the end of platelet transfusion blood samples will be drawn and treated with…
- Trial name
- FiT2012 (NCT01955811)
- Testing
- Administration of platelet concentrate and taking blood samples
- Where
- 5 sites in Austria, Denmark
- Volunteers
- 130 people
- Sponsor
- Medical University Innsbruck
Pulp Necroses
Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth
The aim of the present study is to assess clinically and radio-graphically the regenerative potential of immature permanent teeth with necrotic pulp using blood clot and Platelet rich fibrin scaffolds.
- Trial name
- NCT04390854
- Testing
- Blood clot scaffold, Blood clot scaffold combined with PRF
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nourhan M.Aly
Venous Thrombosis, Deep Vein Thrombosis
Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer
This is a multicenter, cohort study evaluating an adapted rivaroxaban dose regimen in patients with acute, proximal deep-vein thrombosis (DVT) or acute pulmonary embolism (PE) who concomitantly use a strong cytochrome P450…
- Trial name
- NCT00786422
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 16 sites in Australia, Austria and 7 more
- Volunteers
- 25 people
- Sponsor
- Bayer
Thrombosis
Heparin Versus Lepirudin Flushes in Preventing Blockage of Venous Access Devices
This study will compare the effectiveness of two blood thinners, heparin and lepirudin, in preventing withdrawal occlusion (blockage) in a venous access device (VAD).
- Trial name
- NCT00039767
- Testing
- Lepirudin
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Acute Pulmonary Embolism
A Phase II Study to Evaluate the Efficacy of ThromboView® in the Detection of Pulmonary Emboli
The aim of the study is to determine the diagnostic accuracy of 99mTc ThromboView® SPECT imaging for the detection of acute pulmonary embolism (PE) in patients for whom there is a moderate to high clinical suspicion for PE.
- Trial name
- NCT00519506
- Testing
- ThromboView
- Where
- 6 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Agen Biomedical