Clinical trials: Fibromyalgia, Pain
Persistent Physical Symptoms (PPS)
CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)
Brief Summary: Persistent Physical Symptoms (PPS), also known as medically unexplained symptoms (MUS) is a term used to describe a range of persistent bodily symptoms for which the exact cause is unclear.
- Trial name
- PRINCE (NCT02426788)
- Testing
- Cognitive behavioural therapy (CBT)
- Where
- 7 sites in United Kingdom
- Volunteers
- 324 people
- Sponsor
- King's College London
Low Back Pain, Myofascial Pain Syndrome Lower Back
Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial
Rationale: Low back pain (LBP), or myofascial pain syndrome (MPS) of the low back, accounts for approximately 2.63 million visits in the United States, or 2.3 percent of annual Emergency Department (ED) visits.
- Trial name
- T-PIMPS (NCT04704297)
- Testing
- Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below., Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below., Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Chronic Widespread Pain, Fibromyalgia
Prognostic Factors for Work Disability in Patients With Chronic Widespread Pain and Fibromyalgia.
Introduction: The association between chronic widespread pain (CWP) and disability is well-established. Although research support large inter-individual differences in functional outcomes, limited studies are available on the…
- Trial name
- NCT04862520
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Frederiksberg University Hospital
Fibromyalgia, Aromatherapy
The Effect of Peppermint Oil Aromatherapy on Pain, Functional Capacity and Cost in Fibromyalgia Patients
This study was designed to evaluate the effect of topically applied peppermint oil (Mentha × piperita) on chronic pain and functional capacity experienced by fibromyalgia patients, as well as its cost-effectiveness.
- Conditions
- Fibromyalgia, Aromatherapy, Cost
- Trial name
- NCT07326163
- Testing
- Peppermint Oil, sweet almond oil, Duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Pain, Chronic Widespread Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies.
- Conditions
- Pain, Chronic Widespread Pain, Fibromyalgia
- Trial name
- NCT04862871
- Testing
- Physical Activity - Pediatric Pain Rehabilitation Center
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Fibromyalgia, Musculoskeletal Pain
Light Bulb Stimuli to Reduce Chronic Pain
This pilot randomized, double-blind, crossover clinical trial will evaluate the feasibility and preliminary efficacy of chromatic (colored) light exposure for reducing pain severity and pain sensitivity in adults with…
- Trial name
- Light Bulb (NCT07825792)
- Testing
- S-Cone Stimulating Chromatic Light, Equal-Energy White Light
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Fibromyalgia, Fibromyalgia Syndrome
Effectiveness of AI-Guided Exercise and Pain Neuroscience Education for Fibromyalgia (FIBROIA)
This randomized controlled trial will evaluate the effectiveness of a 12-week, home-based telerehabilitation program for adults with fibromyalgia (FM) combining AI-guided exercise with Pain Neuroscience Education (PNE).
- Trial name
- FibroIA (NCT06672419)
- Testing
- AI-Guided Exercise and Pain Neuroscience Education, Enhanced Usual Care for Fibromyalgia
- Where
- 2 sites in Chile, Colombia
- Volunteers
- 50 people
- Sponsor
- Instituto Neurociencia Del Dolor
Myofascial Pain Syndrome, Trigger Point Pain, Myofascial
Pressure Release Versus Thoracic Manipulation in Rhomboids MPS
The purpose of the stud will be to compare the effect of pressure release with thoracic spine manipulation on pain intensity level and pain pressure threshold, thoracic spine ROM and physical function onactive rhomboids muscle…
- Trial name
- NCT05688800
- Testing
- conventional therapy, Experimental group 1 : pressure release technique, Experimental group 2: thoracic spine manipulation
- Volunteers
- 66 people
- Sponsor
- Cairo University
Fibromyalgia
Montage of HTDCS in Psycho-cognitive Functions in FM
This study aims to map the impact of anodic transcranial direct current stimulation (tDCS) for prolonged home use applied to the primary motor cortex and the left dorsolateral prefrontal córtex (DLPFC), compared to the respective…
- Trial name
- HFTDCS (NCT04890964)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fibromyalgia, Chronic Pain
Effectiveness of Dry Needling in Fibromyalgia Patients
Patients with fibromyalgia (FM) complain of widespread chronic pain from deep tissues including muscles. Previous research highlights the relevance of impulse input from deep tissues for clinical FM pain.
- Conditions
- Fibromyalgia, Chronic Pain, Anxiety, Depression
- Trial name
- NCT04942444
- Testing
- Dry needling
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- CEU San Pablo University
Fibromyalgia, Irritable Bowel Syndrome
Clinical Study on Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain
The project investigates on the role of pain avoidance, comorbidity and stress response for the development of chronic somatic and visceral pain.
- Trial name
- NCT00222209
- Testing
- Experimental heat pain model
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Fibromyalgia, Pain
Acupuncture in Fibromyalgia
Fibromyalgia is the second most common rheumatic disorder, affecting approximately 8-10 million persons in the U.S., and is characterized by widespread musculoskeletal pain and soft tissue tenderness upon examination.
- Trial name
- NCT00010504
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Chronic Primary Pain, Musculoskeletal Pain
Facilitators and Barriers in Neuroscience-based Pain Education Programmes in Primary Care Physiotherapy
The new approach in pain neuroscience education (PNE) requires specific training for the physiotherapists in charge of applying it.
- Conditions
- Chronic Primary Pain, Musculoskeletal Pain, Fibromyalgia
- Trial name
- NCT05860816
- Testing
- Survey
- Where
- Spain
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Castilla-León Health Service
Nocturnal Leg Cramps, Myofascial Pain Syndrome
Exercise and Dry Needling Treatment Combination in Nocturnal Calf Cramps
The Investigators aim to evaluate the effectiveness of dry needling treatment in addition to stretching exercises on cramp duration, cramp intensity, cramp frequency, sleep quality, and sensitivity of myofascial trigger points in…
- Trial name
- NCT04789811
- Testing
- Stretching exercise, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kars State Hospital
Myofascial Pain Syndrome (MPS)
Effects of Electrical Muscle Stimulation on Myofascial Pain Syndrome
The goal of this clinical trial is to determine if Electrical Muscle Stimulation (EMS) combined with Active Stretching (AS) (EMS+AS) and EMS+AS combined with Trigger Point Pressure Release (TPR) (EMS+AS+TPR) are effective…
- Trial name
- NCT07315776
- Testing
- Therapist-assisted Passive stretching (PS), The two-combination of EMS+AS, Trigger point pressure release (TPR)
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- University of Bath
Fibromyalgia
CBD (Cannabidiol)/THC (Tetrahydrocannabinol) Solution as a Pharmacological Strategy for Patients With Fibromyalgia (FibroCann)
Fibromyalgia is considered a chronic pain syndrome, non-inflammatory, of unknown etiology, which manifests itself in the musculoskeletal system in up to 2.5% of the general population, predominantly in females, mainly between 35…
- Trial name
- NCT05283161
- Testing
- cannabidiol and tetrahydrocannabinol
- Volunteers
- 40 people
- Sponsor
- FG Brasil LTDA
Fibromyalgia Syndrome, Anxiety Disorders
The Relationship Between Fibromyalgia Syndrome Parameters With Disease-Pain Severity and the Quality Of Life
In this study, the investigators aim to evaluate the relationship between disease severity, quality of life, anxiety and pain level in patients diagnosed with Fibromyalgia Syndrome (FMS) with the parameters according to the…
- Conditions
- Fibromyalgia Syndrome, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05850442
- Testing
- Questionary
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Fibromyalgia, Temporomandibular Disorder
An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia
Nowadays, fibromyalgia is the rheumatic disorder with the highest levels of deterioration in quality of life. Among the comorbidities it presents, one of the most frequent is temporomandibular disorders.
- Trial name
- NCT06365151
- Testing
- Osteopathic manual therapy
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Myofascial Pain Syndrome
Comparative Efficacy of PRP and Dry Needling in Management of Trigger Points in Masseter Muscle in MPS Patients
Title: Comparative Efficacy of Platelet Rich Plasma injection and Dry Needling in management of trigger points in masseter muscle in Myofascial Pain Syndrome patients.
- Trial name
- NCT04286880
- Testing
- PRP injection, Dry needling
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Complex Regional Pain Syndrome (CRPS)
Preceding Pain and Development of Additional Pain in Patients With CRPS
Complex regional pain syndrome (CRPS) is a very painful condition that can have a huge impact on people's lives. Despite progress having been made in understanding what CRPS is and how it affects people, there are still many…
- Trial name
- NCT07838376
- Where
- United Kingdom
- Volunteers
- 705 people
- Sponsor
- Walton Centre NHS Foundation Trust