Clinical trials: Fibrosing Interstitial Lung Disease
Fibrosing Interstitial Lung Diseases, Idiopathic Pulmonary Fibrosis
Yoga in Patients With Fibrosing Interstitial Lung Diseases
Fibrosing interstitial lung diseases are characterized by loss of lung function, which leads to a decrease in quality of life and physical capacity.
- Trial name
- NCT03979703
- Testing
- 12 week yoga class
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- Heidelberg University
Lung Diseases, Interstitial
Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases
The purpose of this study is to evaluate efficacy and safety of olokizumab (OKZ) compared to placebo in patients progressive fibrosing Interstitial lung diseases (ILD).
- Trial name
- NCT06440746
- Testing
- Subcutaneous (SC) injections of OKZ 64 milligrams (mg) every 4 weeks (q4w), one injection of 0.4 millilitre (mL)
- Where
- 33 sites in Russia
- Volunteers
- 138 people
- Sponsor
- R-Pharm International, LLC
Idiopathic Pulmonary Fibrosis
Study of ORJ-001 for the Treatment of IPF
ORJ-001 is a new class of drugs intended for the treatment of patients with idiopathic pulmonary fibrosis (IPF). This is a Phase 2 study in two parts; the objective of Part A will determine if ORJ-001 is well-tolerated by…
- Trial name
- NCT07869147
- Testing
- ORJ-001
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- Oorja Bio, Inc.
Fibrosing Interstitial Lung Disease
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
This study is open to children and adolescents aged 2 to 17 years with interstitial lung disease (ILD). Nerandomilast has just been approved in some countries to help adults with a lung condition called idiopathic pulmonary…
- Trial name
- NCT07366034
- Testing
- Nerandomilast
- Where
- 47 sites in United States, Argentina and 20 more
- Volunteers
- 35 people
- Sponsor
- Boehringer Ingelheim
Fibrosis, Pulmonary, Pulmonary Rehabilitation
The Effect of Exercise Training on Quality of Life and Disease Progression in Fibrosing Interstitial Lung Patients
In this study, the progression of the disease and changes in quality of life will be examined over a 1-year follow-up period in groups of patients with Fibrosing Interstitial Lung Disease who either participated in or did not…
- Trial name
- NCT06527612
- Testing
- Pulmonary rehabilitation exercise programme
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul Medipol University Hospital
Lung Diseases, Interstitial
A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)
The main objective of the study is to evaluate dose-exposure and safety of nintedanib in children and adolescents with fibrosing Interstitial Lung Disease (ILD).
- Trial name
- InPedILD® (NCT04093024)
- Testing
- Nintedanib
- Where
- 43 sites in United States, Argentina and 19 more
- Volunteers
- 39 people
- Sponsor
- Boehringer Ingelheim
Lung Diseases, Interstitial
A Study to Evaluate Long-term Safety of Nintedanib in Children and Adolescents With Interstitial Lung Disease (InPedILD®-ON)
This study is open to children and adolescents with interstitial lung disease (ILD) that causes lung fibrosis. This is a study for people who took part in a previous study called InPedILD (study 1199-0337) and for people who are…
- Trial name
- NCT05285982
- Testing
- Nintedanib (Ofev®)
- Where
- 28 sites in United States, Argentina and 15 more
- Volunteers
- 54 people
- Sponsor
- Boehringer Ingelheim
Fibrosing Interstitial Lung Diseases, Thoracic Ultrasound
Ultrasound Applicability in the Assessment of Patients With Fibrosing Interstitial Lung Disease
In this study the investigators want to examine the different ultrasound techniques to assess the patients with lung fibrosis. The investigators want to followup these patients in 1 year to see the changes in lungs, pleura…
- Trial name
- LORD (NCT06844331)
- Testing
- Thoracic ultrasound
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Odense University Hospital
Lung Diseases, Interstitial, Lung Disease With Systemic Sclerosis
Non-interventional Study Describing Epidemiology, Prognosis and Patient Healthcare Costs in France, 2010-2017
Interstitial lung diseases (ILDs) are a heterogeneous group of disorders, which encompass a wide range of conditions. In some patients with fibrosing ILDs, a progressive phenotype similar to that observed in idiopathic pulmonary…
- Trial name
- PROGRESS (NCT03858842)
- Testing
- epidemiology, healthcare costs in non-IPF PF-ILD and SSc-ILD
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Lung Diseases, Interstitial
A Study to Find Out Whether BI 1015550 Improves Lung Function in People With Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs)
This study is open to adults with Progressive Fibrosing Interstitial Lung Diseases (PF-ILDs). People who have a form of PF-ILD other than Idiopathic Pulmonary Fibrosis (IPF) can join the study.
- Trial name
- NCT05321082
- Testing
- BI 1015550
- Where
- 400 sites in United States, Argentina and 43 more
- Volunteers
- 1,178 people
- Sponsor
- Boehringer Ingelheim
Lung Diseases, Interstitial (in Pediatric Populations), Childhood Interstitial Lung Disease (chILD)
A Treatment Protocol to Support the Care of Children and Adolescents With Fibrosing Interstitial Lung Disease (ILD)
This Expanded Access Program (EAP) is intended to facilitate the availability of OFEV® (nintedanib) to children and adolescents with chronic fibrosing interstitial lung disease (ILD) on top of current standard of care treatment…
- Trial name
- NCT05624281
- Testing
- nintedanib
- Sponsor
- Boehringer Ingelheim
Lung Diseases, Interstitial Lung Disease
Effects of Exercise Training on Respiratory Performance in Patients With Fibrosing Interstitial Lung Diseases
The current study recruited patients with fibrosing interstitial lung diseases (f-ILD) whatever was the underlying pathology. The investigators aimed to compare the effects of aerobic exercises for lower limbs (LL) versus upper…
- Conditions
- Lung Diseases, Interstitial Lung Disease, Fibrosis Lung
- Trial name
- ET-fILD (NCT05227443)
- Testing
- Exercise aerobic training, Upper, lower and breathing (ULB) exercise
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Alexandria University
Assess PID Diagnosis Revision After CMEI Audit, Assess CMEI Recommendations' Impact on Respiratory Health
Domestic Environmental Exposure and Progression of ILD: An Exploratory Case-Control Study
The project titled "Domestic Environmental Exposure and Progression of Progressive or Stable Fibrosing Interstitial Lung Diseases: An Exploratory Case-Control Study" is a Category 3 study involving 60 patients with progressive or…
- Conditions
- Assess PID Diagnosis Revision After CMEI Audit, Assess CMEI Recommendations' Impact on Respiratory Health, ILD Progression and Exposure to Indoor Environnemental Risk, ILD Progression and Exposure to Outdoor Polluants
- Trial name
- EXPODOM-PID (NCT07457502)
- Testing
- Environmental audit of patient housing
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Ville de Paris
Hypersensitivity Pneumonitis
Contribution of the Indoor Environment Medical Advisor in the Management of Fibrosing Hypersensitivity Pneumonitis
Hypersensitivity pneumonitis (HP) is a diffuse infiltrative pneumonitis (DIP) of immuno-allergic origin, caused by exposure to one or more antigenic substances of organic origin, in genetically predisposed individuals.
- Trial name
- PHSaDom (NCT05988437)
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Lung Diseases, Interstitial, Exercise, Compulsive
Muscles Oxygenation During Exercise in Fibrosing Interstitial Lung Diseases
The type of this study is an observational prospective study. It will be done to determine the oxygenation status of the intercostal muscles and quadriceps femoris muscle during exercise in patients with fibrosing lung and to…
- Conditions
- Lung Diseases, Interstitial, Exercise, Compulsive, Oxygen Deficiency
- Trial name
- NCT05855447
- Testing
- NIRS device usage during 6MWT, Peripheral Muscle Strength Measurement, Pulmonary Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Lung Diseases, Interstitial
Efficacy and Safety of Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
The aim of the current study is to investigate the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD) defined as patients who present with features of diffuse…
- Trial name
- INBUILD® (NCT02999178)
- Testing
- Nintedanib
- Where
- 153 sites in United States, Argentina and 13 more
- Volunteers
- 663 people
- Sponsor
- Boehringer Ingelheim
Interstitial Lung Diseases
Advanced Mutidimensional and Ultra High Resolution Computed Tomography to Inspect Cardiopulmonary Involvement in Progressive Fibrosing Interstitial Lung Diseases
Interstitial lung diseases (ILDs) are common chronic disease characterized by high mortality and morbidity, also linked to cardiovascular implication.
- Trial name
- AMICI-ILD (NCT06537934)
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- IRCCS San Raffaele
Idiopathic Pulmonary Fibrosis
Azathioprine and Prednisone in the Treatment of Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a diffuse lung disease, associated with the histological appearance of usual interstitial pneumonia (UIP), with an inexorably deteriorating clinical course.
- Trial name
- NCT00518310
- Testing
- AZAPRED
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Thorax National Institute
Fibrosing Interstitial Lung Disease, Telerehabilitation
Telerehabilitation in Patients With Fibrosing Interstitial Lung Diseases
The aim of the study is to determine the effectiveness of different exercise programs applied to 3 groups randomly formed in patients with fibrosing interstitial lung disease (FILD).
- Trial name
- NCT05166057
- Testing
- Synchronized online telerehabilitation exercise program, Videobased telerehabilitation exercise program, Hospital based outpatient exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Saglik Bilimleri Universitesi
Sarcopenia
Evaluation of Frailty in Patients With Fibrosing Interstitial Lung Diseases: Prognostic and Therapeutic Impact
Fibrosing interstitial lung diseases (ILDs), with idiopathic pulmonary fibrosis being the most common form, primarily affect older individuals and have a poor prognosis, with a median survival of 3 to 5 years.
- Trial name
- FRAPID (NCT07004595)
- Testing
- Evaluation of patient frailty
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital