Clinical trials: Fine-needle Aspiration
Pancreatic Cancer, Pancreatic Neoplasms
Intermittent Suction Technique in the Diagnosis of Pancreatic Solid Lesions
The aim of this study is to compare the diagnostic yield of intermittent versus continuous suction in the diagnosis of pancreatic solid lesions.
- Trial name
- NCT03829748
- Testing
- Intermittent aspiration
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Breast Cancer Diagnosis
Automated Method for Breast Cancer Detection
Participants with suspicious breast lesions by mammography will undergo fine needle aspiration (FNA) under ultrasound guidance. The FNA will be read by the cytopathologist and analyzed in the breast cancer detection cartridge.
- Trial name
- NCT03863522
- Testing
- Fine needle aspiration, Cancer Detection cartridge
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pancreatic Adenocarcinoma
The Impact Of Tissue Micro-RNA Profile From EUS-FNA In Pancreatic Adenocarcinoma
Pancreatic adenocarcinoma still represents one of the "hot-topics" worldwide. Endoscopic ultrasonography was a breakthrough, bringing us closer to personalized treatment by getting histopathological samples through…
- Trial name
- EUS-FNA (NCT04765410)
- Testing
- EUS FNA (endoscopic ultrasound fine needle aspiration)
- Where
- 5 sites in Romania
- Volunteers
- 57 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Uterine Bleeding
Effects of Lidocaine Spray for Reducing Pain During Endometrial Aspiration Biopsy : a Randomized Controlled Trial
Endometrial aspiration biopsy has been accepted as a diagnostic procedure of choice for women with abnormal uterine bleeding to examine endometrial pathology.
- Trial name
- NCT03075358
- Testing
- Lidocaine spray, Normal saline spray
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Chiang Mai University
Portal Vein Thrombosis
Role of EUS Guided FNA of Portal Vein Thrombus in the Diagnosis and Staging of Hepatocellular Carcinoma
Since not every portal vein thrombus (PVT) in a patient with hepatocellular carcinoma (HCC) is a tumor thrombus, since the nature of the thrombus will ultimately determine the course of treatment, and since PVT may be even the…
- Trial name
- NCT03902678
- Testing
- EUS guided fine needle aspiration of portal vein thrombus
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Adenocarcinoma, Carcinoma
Anatomical-Clinical Base of Adenocarcinoma Pancreatic
BACAP-2 is a prospective biobank dedicated to the pancreatic adenocarcinoma including clinical data and biological samples from tumor.
- Conditions
- Adenocarcinoma, Carcinoma, Neoplasms
- Trial name
- BACAP-2 (NCT06128343)
- Testing
- collection of biological samples
- Where
- 8 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Toulouse
Neuroendocrine Tumours
68-Ga-labeled Octreotide Analogues PET in Duodenal-pancreatic Neuroendocrine Tumours
The diagnostic work-up of patients suspected of having neuroendocrine tumours (NETs) has traditionally been a challenging issue.
- Trial name
- NCT01673906
- Testing
- Diagnostic work up
- Where
- 21 sites in Austria, Italy
- Volunteers
- 142 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Pancreatic Cancer, Solid Pancreatic and Peripancreatic Lesion
Yield Rate for Procurement the Histologic Core With Endoscopic Ultrasound-guided Fine Needle Biopsy With 20-gauge Ultrasound Biopsy Needles for Solid Pancreatic Masses: Pilot Study
To investigate the technical feasibility and diagnostic yield of new 20-gauge Procore needle for EUS-guided fine needle biopsy in pancreatic solid lesions.
- Trial name
- NCT03017599
- Testing
- 20-gauge ProCore FNB needle
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Pancreatic Neoplasms
Comparative Study of 22 and 25 Gauge ProCore EUS-guided Biopsy in Pancreatic Mass
Background: EUS-guided fine needle aspiration (FNA) is a major diagnostic tool in the patient with pancreatic mass with high specificity, specificity and accuracy.
- Trial name
- NCT01727921
- Testing
- 22 gauge ProCore needle biopsy, 25 gauge ProCore needle biopsy
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Samsung Medical Center
Chronic Hepatitis b
Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected Patients
Two hundred and ninety-six million people worldwide are chronically infected with the hepatitis B virus (HBV), with around 750,000 deaths each year linked to the development of cirrhosis or hepatocellular carcinoma.
- Trial name
- RES-HBV (NCT06047093)
- Testing
- Investigation of the intrahepatic compartment using the fine needle aspiration (FNA) technique, Creation of a serum biobank, FNA feasibility and acceptability questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Pancreatic Disease
Endoscopic Ultrasound-guided Fine-needle Aspiration of Solid Pancreatic Lesions With Rapid Staining of Cytological Smears Followed by Whole Slide Scanning and Artificial Intelligence Diagnosis: A Prospective, Multicenter Study.
The objective of this observational study is to investigate whether the self-developed whole slide scanning and artificial intelligence diagnostic system for pancreatic solid lesion puncture cytopathology (hereinafter referred to…
- Trial name
- NCT06824909
- Testing
- ROSE-AI diagnostic system
- Where
- 2 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Ruijin Hospital
Solitary Pulmonary Nodule, Biopsy, Fine-Needle
iNod System Human Feasibility Assessment
The purpose of this study is to demonstrate feasibility to access, visualize, and obtain specimens adequate for cytology of lung lesions in subjects with suspected lung cancer when using the iNod System.
- Trial name
- iNod (NCT02832284)
- Testing
- iNod System
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Boston Scientific Corporation
Insulinoma
EUS-guided Ethanol Ablation of an Insulinoma
The present study aims to evaluate the feasibility, safety and efficacy of EUS-guided ethanol ablation of an insulinoma.
- Trial name
- EUS (NCT02121366)
- Testing
- EUS-guided ethanol ablation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Guangxi Medical University
Pancreatic Tumor, Fine Needle Aspiration
Comparison of Two Needles (ProCore vs EchoTip) for the Diagnosis of Pancreatic Solid Mass Under EUS
The negative predictive value of fine needle aspiration under ultrasound endoscopy (EUS) for the diagnostic of solid pancreatic masses is 70% on average in the current literature with 22 gauge needles.
- Conditions
- Pancreatic Tumor, Fine Needle Aspiration, Endoscopic Ultrasonography
- Trial name
- PICORE (NCT01479803)
- Testing
- Puncture with fine needle aspiration under endoscopic ultrasonographic control
- Where
- France
- Volunteers
- 80 people
- Sponsor
- VANBIERVLIET
Solid Pancreatic Lesions, EUS-FNB
Comparision of EUS-FNB Techniques for Diagnose of Solid Pancreatic Lesions
Studies have shown that the wet-suction technique in EUS-FNA generates better histological diagnostic accuracy and specimen quality than the dry-suction technique.
- Trial name
- NCT05549856
- Testing
- Wet suction, Dry suction
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Pancreas Neoplasms
Comparing of a 22G EUS Procore Fine Needle Biopsy Device and a 20G EUS Procore Fine Needle Biopsy Device
The purpose of this study is to compare the diagnosis accuracy of 22G EUS Procore fine needle biopsy （FNB）device and 20G EUS Procore fine needle biopsy device for solid pancreatic lesions.
- Trial name
- NCT03803930
- Testing
- Using 22G FNB, the first pass is SP, Using 22G FNB, the first pass is MWST, Using 20G FNB, the first pass is SP
- Where
- China
- Volunteers
- 1,224 people
- Sponsor
- Huazhong University of Science and Technology
Cancer of Pancreas, Pancreatic Neoplasm
Trial Comparing 19 and 25-gauge EUS-FNA Needles
This study compares the 19G and 25G needles for procuring tissue samples from the pancreas during Endoscopic Ultrasound (EUS) procedures.
- Trial name
- EUS-FNA (NCT01677312)
- Testing
- Pancreatic Biopsy, Histological Samples
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- AdventHealth
EUS Guided Biopsy
SharkCore Versus Acquire FNB
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been established as an effective technique for sampling tissue inside and around the gastrointestinal tract, including the pancreas, liver, lymph nodes, and…
- Trial name
- NCT03672032
- Testing
- Fork-tip Needle, Franseen Needle
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Henning Gerke
Breast Cancer
Modulation of Breast Cancer Risk Biomarkers by High Dose Vitamin D
The overall goal of this project is to determine if high dose vitamin D3 given to premenopausal women at high risk for development of breast cancer, who initially have insufficient levels of 25-hydroxy vitamin D (<30 ng/ml), will…
- Trial name
- NCT01166763
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carol Fabian, MD
Pancreatic Cancer
Prospective Evaluation of Diagnostic Accuracy of Endoscopic Ultrasound-guided Fine Needle Aspiration and Biopsy (EUS-FNAB) in the Absence of Rapid Onsite Evaluation
<Background/aims> Rapid onsite evaluation (ROSE) of endoscopic ultrasound-guided fine needle aspiration and biopsy (EUS-FNAB) specimens by attending cytopathologists has been demonstrated to improve diagnostic yields of EUS-FNAB.
- Trial name
- FNASROSE (NCT02079285)
- Testing
- EUS-FNA
- Where
- 2 sites in South Korea
- Volunteers
- 75 people
- Sponsor
- Kangbuk Samsung Hospital