Clinical trials: Fine-needle Aspiration
Thyroid Nodule
Compliance of Thyroid Fine Needle Aspiration Biopsy and Trucut Biopsy Results With TIRADS Score and Surgical Pathology
The investigators retrospectively reviewed the medical records of 760 patients with thyroid nodule biopsy and 88 patients who had thyroid surgery.
- Trial name
- TIRADS (NCT04488640)
- Testing
- Thyroid biopsy with ultrasound
- Volunteers
- 4 people
- Sponsor
- Bezmialem Vakif University
Pancreatic Ductal Adenocarcinoma
A Clinical Study to Evaluated Which Number of Passes of EUS-FNB is Better for Culturing Primary Cells of PDAC
The Aim of this study is to investigate the amount of tissue required for the successful culture of primary cells from human-derived pancreatic ductal adenocarcinoma which obtained by endoscopic ultrasound-guided fine-needle…
- Trial name
- NCT04794140
- Testing
- different number of passes
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Thyroid Cancer
New Thyroid Fine Needle Aspiration Biopsy Apparatus
Evaluation of the effectivity of the new thyroid fine needle aspiration biopsy (FNAB) apparatus of which patented from Turkish Patent Institute.
- Trial name
- fnab (NCT01512212)
- Testing
- biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- SB Istanbul Education and Research Hospital
Non Small Cell Lung Cancer
Study Comparing EBUS & EUS to Mediastinoscopy in Staging and Detection of Lung Cancer
This is a prospective randomized clinical trial with the study cohort comprised of all male and female patients over the age of 21 presenting to the study site for evaluation of lung cancer.
- Trial name
- NCT00970645
- Testing
- Mediastinoscopy/thoracoscopy, EBUS/EUS
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Infertility, Female, Recurrent Miscarriage
Immune Cell Populations in the Endometrium
Specialized immunological studies in the diagnostics of idiopathic infertility and recurrent miscarriages have limited applicability, as the role of the immune system in these conditions is not thoroughly understood.
- Conditions
- Infertility, Female, Recurrent Miscarriage, Gynecologic Disease
- Trial name
- NCT06826365
- Testing
- Percentage distribution of immune system cells in peripheral blood, Percentage distribution of immune system cells in endometrium
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Jagiellonian University
Endometrial Hyperplasia
Comparison of Dilatation & Curettage and Endometrial Aspiration Biopsy Accuracy in Patients Treated With Progestin for Endometrial Hyperplasia: A Korean Gynecologic Oncology Group Study
A prospective multicenter trial has been started in Korea to evaluate the diagnostic accuracy of endometrial aspiration biopsy compared with D\&C in patients treated with progestin for endometrial hyperplasia (EH).
- Trial name
- NCT02412072
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Korean Gynecologic Oncology Group
Pancreatic Adenocarcinoma, Pancreas Cancer
Repeated EUS-guided Fine Needle Biopsy of Pancreatic Masses After Non-diagnostic or Inconclusive Results
The primary aim of REuBio study is to evaluate the diagnostic accuracy of repeated endoscopic ultrasound-guided fine needle biopsy after a previous non-diagnostic or inconclusive EUS-guided sampling of solid pancreatic lesions.
- Conditions
- Pancreatic Adenocarcinoma, Pancreas Cancer, Pancreas Metastases
- Trial name
- REuBio (NCT05226572)
- Testing
- endoscopic ultrasound-guided fine needle biopsy
- Where
- Italy
- Volunteers
- 462 people
- Sponsor
- University of Bologna
Pancreatic Cancer
Evaluating the Number of Passes Required for Diagnostic Cell Block During EUS-FNA of Solid Pancreatic Mass Lesions
This study will test the amount of tissue, called "cell block", obtained from your pancreas. Patients who are asked to participate in this study have a growth (mass) in the pancreas that needs a biopsy so a diagnosis can be made.
- Trial name
- NCT01809028
- Testing
- EUS FNA with 2 passes, EUS FNA with 4 passes
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- AdventHealth
Lung Cancer
Trial of Endobronchial Ultrasound Guided Fine Needle Aspiration Techniques
Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) techniques have not been well studied. The investigators will conduct a randomized study comparing the diagnostic yield and specimen quality of…
- Trial name
- NCT01741571
- Testing
- EBUS guided FNA with and without suction
- Where
- Lebanon
- Volunteers
- 32 people
- Sponsor
- American University of Beirut Medical Center
Breast Neoplasms
Study of Tumor RNA Disruption Assay™ (RDA)
The purpose of this study is to find out if the pathological complete response (pCR) to chemotherapy given before surgery (neoadjuvant chemotherapy) could be predicted by the evaluation of the RNA (ribonucleic acids) disruption…
- Trial name
- RnaDx (NCT02239315)
- Testing
- Tumor RNA Disruption Assay™ (RDA)
- Where
- 4 sites in Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Adenocarcinoma of Head of Pancreas
Comparison of Two Needles (19G Flex Versus 22G Standard) for Pancreatic Solid Tumors Diagnosis
The purpose of this study is to compare the diagnostic gain between 22G standard needle vs 19G Flex needles transduodenal punctures of masses of the pancreatic head.
- Trial name
- EASYFLEX (NCT02078232)
- Testing
- puncture of head of pancreas
- Where
- France
- Volunteers
- 124 people
- Sponsor
- French Society of Digestive Endoscopy
Efficacy, Self
Diagnostic Efficacy Of 3 EUS-FNB Techniques
Endoscopic ultrasound (EUS) is a widely recognized tool for over 30 years for diagnosing intra-abdominal lesions and gastrointestinal cancers, especially pancreatic neoplasia.
- Trial name
- NCT05825729
- Testing
- Dry suction technique (A), Slow-pull technique (B), Wet suction technique (C)
- Where
- 2 sites in Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Insular Gran Canaria
Pancreatic Cancer
Training Endoscopists to Perform On-site Rapid Cytological Evaluation for EUS-FNA of Solid Pancreatic Lesions
In China, there is a serious shortage of pathologists who can perform on-site cytological diagnosis. As a result, there are few centers that can conduct ROSE in China, which limits the diagnostic accuracy of EUS-FNA to a certain…
- Trial name
- EUS-FNA (NCT04509687)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Hepatic Cancer, Hepatic Neoplasm
Endoscopic Ultrasound Guided Liver Biopsy
This is a prospective study to determine the optimal technique for obtaining liver tissue with a smaller caliber (22 gauge) needle and whether a good core biopsy can be obtained without the use of suction and secondly to…
- Conditions
- Hepatic Cancer, Hepatic Neoplasm, Hepatic Carcinoma
- Trial name
- NCT03307811
- Testing
- 22 gauge needle liver biopsy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AdventHealth
Solid Tumor
EUS-FNA for Patients With Antithrombotic Agents
The purpose of this study to evaluate a safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for patients with antithrombotic agents.
- Trial name
- NCT01798654
- Where
- Japan
- Volunteers
- 84 people
- Sponsor
- Hokkaido Pancreatobiliary Endoscopic Intervention Study Group
Diagnoses Disease
Atypia of Undetermined Significance (AUS) / Follicular Lesion of Undetermined Significance (FLUS)
According to the guidelines for reporting thyroid fine needle aspirations known as The Bethesda System, the category of atypical cells known as AUS/ FLUS category has an estimated rate of 5 to 15% for malignancy.
- Trial name
- NCT03224754
- Testing
- Determination of risk of malignancy of these thyroid lesions
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Immunocompromised
Diagnosis of Invasive Pulmonary Aspergillosis by Direct Lung Tissue Aspergillus Galactomannan Antigen Detection From Aspirate by Ultrasound-guided Fine Needle Aspiration
Invasive aspergillosis is a serious and often fatal infection in patients who are neutropenic or have undergone solid organ or stem cell transplantation. However, early diagnosis of invasive aspergillosis is a challenge.
- Trial name
- NCT01301755
- Testing
- Lung aspiration
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Suspicious for Papillary Thyroid Carcinoma
Role of Cytomorphometry and BRAFV600E Immunocytochemistry With a Cytologic Diagnosis "Suspicious for Papillary Thyroid Carcinoma"
Thyroid nodules (TNs) are a common finding, detected by ultrasound in about 70% of healthy individuals, with women being four times more affected.
- Trial name
- NCT06901908
- Volunteers
- 45 people
- Sponsor
- Assiut University
Gastrointestinal Neoplasm, Mass Lesion
AI for Onsite Cytology Evaluation in Endoscopic Ultrasound
The aim of this study is to determine if the widely available artificial intelligence platform ChatGPT can accurately identify the abnormalities present on cytology specimens obtained at EUS-FNB of solid mass lesions in the…
- Trial name
- NCT07228689
- Testing
- EUS-guided fine needle biopsy
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Orlando Health, Inc.
Pancreatic Adenocarcinoma
Biological and Clinical Database for Pancreatic Adenocarcinoma
BACAP is a biobank dedicated to the pancreatic adenocarcinoma funded by institut national institue du cancer (INCa) and coordinated by Dr Barbara Bournet from Toulouse hospital.
- Trial name
- BACAP (NCT02818829)
- Testing
- Collection of biological samples
- Where
- 16 sites in France
- Volunteers
- 1,700 people
- Sponsor
- University Hospital, Toulouse