Clinical trials: Fine-needle Aspiration
Pancreas Adenocarcinoma, Pancreas Neoplasms
EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration
Endoscopic ultrasound (EUS) is a well-established tool for the diagnosis and staging of many gastrointestinal conditions, including but not limited to, malignant and pre-malignant neoplasms of the pancreas, esophagus, rectum, and…
- Conditions
- Pancreas Adenocarcinoma, Pancreas Neoplasms, Gastrointestinal Stromal Tumor, Lymphoma
- Trial name
- NCT01774162
- Testing
- Fine needle biopsy using ProCore needle for histology., Fine needle aspiration using conventional FNA for cytology
- Where
- 2 sites in Canada
- Volunteers
- 57 people
- Sponsor
- University of Alberta
Solid Tumor, Histological Type of Neoplasm
A Randomized Prospective Comparison of the New EUS Guided Acquire TM Needle Biopsy vs EUS Guided Fine Needle Aspiration for Suspected Solid Gastrointestinal Lesions
Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is the technique of choice to evaluate solid gastrointestinal (GI) lesions.
- Trial name
- NCT03109639
- Testing
- Conventional EUS FNA needle, Acquire FNB device
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Singapore General Hospital
Indeterminate Thyroid Cytology
Validation of a Multi-Genetic Test for the Diagnosis of Indeterminate Thyroid Nodules
A clinical trial is proposed, to clinically validate the diagnostic performance of a new genetic test developed in Chile. It will determine the nature of thyroid nodules that have been informed as indeterminate by cytology…
- Trial name
- CT-DS (NCT03061318)
- Where
- 9 sites in Chile
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Hernán González
Lung Cancer
US NAB With ROSE Versus US FNAB With no ROSE
This is an investigator-initiated, single center, controlled, randomized clinical trial with two parallel arms in a 1:1 ratio. The objective of the study is to systematically assess the influence of rapid on-site evaluation…
- Trial name
- NCT04618874
- Testing
- Rapid on-site evaluation
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Thyroid Cancer
An Easy Sonographic Scoring System for Predicting Malignant Thyroid Nodules
The purpose of the investigators study is to retrospectively evaluate the predictors of malignant thyroid nodules and established an useful scoring system based on sonographic findings and demographic data.
- Trial name
- NCT01307761
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Far Eastern Memorial Hospital
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
iNod™ Ultrasound-Guided Needle Biopsy System Study
The purpose of this study is to collect information on the iNod™ System's safety and ability to see the iNod™ biopsy needle in real-time in endobronchial lesions, peripheral lung nodules, or lung masses.
- Conditions
- Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Biopsy, Fine-Needle
- Trial name
- NCT05804435
- Testing
- iNod™ System
- Sponsor
- Boston Scientific Corporation
Thyroid Cancer
Factors Influencing Inadequacy in Rapid Onsite Evaluation of Ultrasound Guided Fine Needle Aspiration (FNA) Samples of Thyroid Nodules
Thyroid nodules are a common clinical finding with a prevalence of around 50-67% in the general population using ultrasound examinations.
- Trial name
- FNA inadequacy (NCT06984991)
- Testing
- fine needle aspiration
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University
Parathyroid Adenoma, Hypercalcemia
Preoperational Fine Needle Aspiration of Pathological Parathyroid Gland
Identification and localization of pathological parathyroid gland before parathyroidectomy is traditionally done by a combination of two methods: ultrasound and sestamibi scan.
- Trial name
- NCT03516747
- Testing
- pre operative parathyroid hormone level measurement, pre operative parathyroid cytology, parathyroid hormone level measurement
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel
Thyroid Cancer, Thyroid Nodules
ctDNA in Patients With Thyroid Nodules
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Thyroid Cancer, Thyroid Nodules, Thyroid Adenoma, Thyroiditis
- Trial name
- NCT02778412
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Pathway Genomics
Bone Marrow Cancer, Leukemia
Improving Patient Experience: BMBA
This study seeks to determine if patients undergoing a bone marrow biopsy/aspiration (BMBA) procedure who receive distraction techniques have lower levels of distress and pain, and higher post-procedure satisfaction, compared to…
- Conditions
- Bone Marrow Cancer, Leukemia, Lymphoma, Multiple Myeloma
- Trial name
- NCT05690230
- Testing
- Virtual reality, Environmental changes
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
A pilot study to assess the effects of six months of letrozole on breast tissue risk markers in postmenopausal women on hormone replacement therapy at high risk of developing breast cancer.
- Trial name
- NCT00291135
- Testing
- letrozole
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carol Fabian, MD
Thermal Ablation, Fine Needle Aspiration Biopsy
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process.
- Conditions
- Thermal Ablation, Fine Needle Aspiration Biopsy, Thyroid Nodules
- Trial name
- CYTOTHYRAF (NCT05726981)
- Testing
- Fine needle aspiration biopsy (FNAB)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fine Needle Aspiration Cytology, Thyroid Diseases
Accuracy of FNAC in Thyroid Nodules Compared to to Surgical Specimen : QOC Experience
Thyroid gland diseases are the second most common endocrine disease following diabetes mellitus(1). Thyroid nodules are common disorders with a prevalence ranged from 4 to 7% in adult population, 5%-30% are malignant…
- Trial name
- Thyroid FNAC (NCT05521594)
- Testing
- Fine Needle Aspiration Cytology
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Qena Oncology Center
Pancreatic Cancer, Stomach Neoplasms
Modified Wet Suction Versus Capillary Techniques for EUS Guided Fine Needle Aspiration and Biopsy of Solid Lesions
The purpose of the study is to compare two particular techniques of tissue (capillary vs wet-suction techniques) sampling during endoscopic ultrasound guided fine needle aspiration/biopsy (EUS-FNA/FNB) of a solid lesion to…
- Trial name
- NCT02919553
- Testing
- modified wet-suction technique, Capillary "slow pull" technique
- Sponsor
- Loma Linda University
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Papillary Thyroid Cancer
Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples
The purpose of this study is to determine whether results from a fine needle biopsy are the same as results from a larger sample that is acquired from the surgical pathology using the Thyroid GuidePx® test in patients with…
- Trial name
- NCT06133374
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- University of Calgary
Mediastinal or Intra-abdominal Lymphadenopathy,, Pancreatic Masses,
A Randomized Controlled Trial Of Endoscopic Ultrasound-Guided Fine-Needle Aspiration With And Without A Stylet
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has become an important tool in the diagnostic evaluation of gastrointestinal tract lesions and other organ sites such as mediastinal and intra-abdominal…
- Conditions
- Mediastinal or Intra-abdominal Lymphadenopathy,, Pancreatic Masses,, Left Adrenal Masses,, Gastrointestinal Submucosal Lesions, and
- Trial name
- NCT01213290
- Testing
- EUS - FNA with stylet, Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- American Society for Gastrointestinal Endoscopy
Parotid Neoplasm, Parotid Cancer
Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms
Parotid gland tumors are mostly treated surgically, but the extent of parotidectomy is decided upon preoperative work-up information.
- Trial name
- NCT03849482
- Testing
- Multiparametric Magnetic Resonance Imaging, Fine Needle Aspiration Cytology, Clinical Evaluation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Davide Di Santo
Chronic Hepatitis C
Evaluating Fine Needle Aspiration to Measure Hepatic Vaniprevir (MK-7009) Concentrations in Participants With Chronic Hepatitis C (MK-7009-048)
This study will evaluate the technical feasibility of using fine needle aspiration (FNA) of liver tissue to obtain vaniprevir (MK-7009) liver pharmacokinetic (PK) data, working towards identifying a minimally invasive…
- Trial name
- NCT01678131
- Testing
- Vaniprevir 600 mg, Peg-IFN alfa-2b, Ribavirin
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Locally Advanced Unresectable Uveal Melanoma
Neoadjuvant Tebentafusp for Uveal Melanoma
This is a prospective, single arm, phase II clinical trial of neoadjuvant Tebentafusp (KIMMTRAK®) in patients with locally advanced primary uveal melanoma.
- Trial name
- NCT06414590
- Testing
- Tebentafusp-Tebn
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Thomas Jefferson University