Clinical trials: Finger
Fracture Fixation, Internal, Metacarpal Fracture
The Effect of Forearm Nerve Blocks on Pain-free Tourniquet Time Compared to Local Anesthetic for Awake Hand Surgery
Wide-awake surgery with local anesthesia is a widely described approach to performing numerous minor hand procedures, such as tendon repairs and percutaneous fracture pinning, but is less frequently used for longer procedures…
- Conditions
- Fracture Fixation, Internal, Metacarpal Fracture, Finger Fracture, Anesthesia, Local
- Trial name
- NCT04787835
- Testing
- Forearm nerve block, Local anesthetic infiltration
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Cerebrovascular Accident
FINGER Robot Therapy Study
The purpose of this study is to determine the effectiveness of training hand movement using FINGER robot after stroke. FINGER is a robot that measures finger movements and allows users to play computer games using those movements.
- Trial name
- NCT02048826
- Testing
- FINGER I, FINGER II
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Irvine
Carpal Tunnel Syndrome, Trigger Finger
Tourniquet vs. No Tourniquet for Carpal Tunnel and Trigger Finger Release
Background: Trigger finger and carpal tunnel syndrome are two of the most common conditions treated by the hand surgeon. During these procedures, a tourniquet is often used to minimize bleeding and improve visualization of the…
- Trial name
- NCT04354415
- Testing
- Carpal tunnel or trigger finger release
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Hemophilia B
Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia B
The purpose of the study is to evaluate the safety, tolerability and effect on FIX antigen and activity levels of ascending doses of SB-FIX.
- Trial name
- NCT02695160
- Testing
- SB-FIX
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sangamo Therapeutics
Trigger Finger, Splint Therapy
Comparative Evaluation of Finger Splint, Paraffin, and Peloidotherapy Interventions in the Management of Trigger Finger
Patients aged 18-75 years who present with trigger finger to a tertiary rehabilitation hospital and agree to participate will be included in the study.
- Conditions
- Trigger Finger, Splint Therapy, Paraffin Bath, Peloidotherapy
- Trial name
- NCT07256522
- Testing
- Finger orthosis, Paraffin bath, Peloidotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
CHİLD
The Effects of Finger Painting During Nebulization Therapy on Fear and Anxiety Levels in Children
Aim: This study was conducted to evaluate the effects of finger-painting intervention administered during nebulization therapy on the fear and anxiety levels of children.
- Trial name
- NCT07885527
- Testing
- the finger-painting
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Firat University
Pain, Amputation Neuroma
Pain After Proximal Digital Amputation Prevention
Finger amputations are common and may be complicated by debilitating nerve pain. This study seeks to determine if nerve pain after digital amputation can be more effectively prevented with either of two new surgical…
- Conditions
- Pain, Amputation Neuroma, Amputation
- Trial name
- PAPDAP (NCT04378062)
- Testing
- Digital nerve procedure
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Indiana University
Cognitive Decline, Cognitive Impairment
METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia
Dementia is the main cause of disability in older adults, currently affecting about 50 million people world-wide with this number estimated to triple in the next 30 years.
- Conditions
- Cognitive Decline, Cognitive Impairment, Dementia
- Trial name
- MET-FINGER (NCT05109169)
- Testing
- FINGER 2.0 multidomain lifestyle-based intervention, Self-guided multidomain lifestyle intervention
- Where
- 3 sites in Finland, Sweden and 1 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Nail Abnormalities
Pilot Study of Efficacy of Nail Gel in Finger Nail Surface Abnormality
Nail surface abnormalities is any conditions that affect the nail matrix or nail bed which cause nail plates grow defectively. Common nail surface abnormalities are pitting nails, longitudinal ridging, and transverse…
- Trial name
- NCT02582762
- Testing
- Nail gel
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Motor Recovery
BreEStim for Motor Recovery in Chronic Stroke With Severe Impairment (Pilot)
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750564
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Human Immunodeficiency Virus (HIV)
Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART
The purpose of this study is to evaluate the safety and tolerability of repeat doses of T-cell immunotherapy (SB-728mR-T) following cyclophosphamide conditioning. CCR5 is a major co-receptor for HIV entry into T-cells.
- Trial name
- NCT02225665
- Testing
- SB-728mR-T, Cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Sangamo Therapeutics
HIV Infections
CCR5-modified CD4+ T Cells for HIV Infection
A Comparative Study of Autologous CD4+ T Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 versus ex vivo Expanded Unmodified Autologous CD4+ T Cells in Treated HIV-1 Infected Subjects
- Trial name
- TRAILBLAZER (NCT03666871)
- Testing
- SB-728-T, Expanded unmodified autologous CD4+ T cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Trigger Finger, Stenosing Tenosynovitis
Resection of Flexor Digitorum Superficialis Tendon for Severe Trigger Fingers
The purpose of this study is to compare the effectiveness of resection of one or both slips of the flexor digitorum superficialis tendon versus the A1 pulley division.
- Trial name
- NCT04675892
- Testing
- A1 pulley division, A1 pulley division + Resection of one or both slips of the FDS tendon
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Colorectal Cancer
A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)
This is a Phase II, open label, multicentre, multi-arm, study to evaluate the preliminary efficacy and safety of RXC004 as monotherapy and in combination with nivolumab in patients with Ring finger protein 43 (RNF43) or R-spondin…
- Trial name
- NCT04907539
- Testing
- RXC004, Nivolumab, Denosumab
- Where
- 22 sites in United States, South Korea and 2 more
- Volunteers
- 25 people
- Sponsor
- Redx Pharma Ltd
COPD
Finger Wearable Device to Monitor Heart Rate Variability and Oxygen Saturation
Introduction: Chronic obstructive airway disease (COPD) is common condition in old age and the perception of hypoxia is often impaired in some COPD patients.
- Trial name
- NCT03268538
- Where
- Hong Kong
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Finger Replantation
Assessment of Functional Outcomes Following Successful Finger Replantation
The functional outcomes following finger replantation are assessed using a combination of objective measures such as grip strength, range of motion, and sensory testing and subjective evaluations, such as patient-reported…
- Trial name
- NCT07029763
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
HIV
Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients
The purpose of the study is to evaluate the safety and feasibility of administering SB-728mR-HSPC after conditioning with busulfan.
- Trial name
- NCT02500849
- Testing
- SB-728mR-HSPC Infusion 3 days following busulfan conditioning
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- City of Hope Medical Center
Acoustic Stimulation, Parkinson Disease
Rhythmic Auditory Stimulation on Neural Activity During Finger-tapping in PD Patients
Introduction Bradykinesia (i.e., slow movements) is one of the most prominent symptoms of Parkinson's disease (PD) and has a negative impact on quality of life.
- Conditions
- Acoustic Stimulation, Parkinson Disease, Electroencephalography
- Trial name
- NCT05839821
- Testing
- noF-noRAS, F-noRAS, noF-100RAS
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
HIV, HIV Infections
Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV
This research study is being carried out to study a new way to possibly treat HIV. This agent is called a "Zinc Finger Nuclease" or ZFN for short. ZFNs are proteins that can delete another protein named CCR5.
- Trial name
- Zinc-Finger (NCT00842634)
- Testing
- ZFN modified T cells, Structured Treatment Interruption
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Oral Leukoplakia
Analyzing Handprint Patterns to Predict Oral Cancer Risks: A Comparative Study
Aims: To evaluate the qualitative and quantitative parameters of finger and palmar dermatoglyphic patterns in patients with oral premalignant and malignant lesions OBJECTIVES: 1.
- Trial name
- QQA-FPD-PMML (NCT06256809)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Khalid University