Clinical trials: Finger
Advanced Solid Tumours
A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2)
This study is to evaluate the preliminary efficacy and safety of RXC004 monotherapy and in combination with pembrolizumab in advanced solid tumours that have progressed following SoC treatment.
- Trial name
- KEYNOTE-E86 (NCT04907851)
- Testing
- RXC004, Denosumab, pembrolizumab
- Where
- 13 sites in Australia, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Redx Pharma Ltd
Hypermobility of Interphalangeal Joints, Swan-Neck Deformity
Splint Users' Satisfaction and Functional Status With Custom Finger Splints
This feasibility and non-randomized comparison study explores the possible benefits of splint design and production by 3D-printing in a clinical setting and looks at splint users' experiences with customizable 3D-printed finger…
- Trial name
- NCT05903391
- Testing
- 3D-Printed Finger Splints, Conventional Finger Splints
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Endeavor Health
Epidermolysis Bullosa Dystrophica
Proof of Concept Study for a Dressing Glove
Epidermolysis Bullosa (EB) is a group of genetic conditions causing extensive, painful skin blisters and wounds. Four main types of EB are recognised, which all affect the hands but those patients usually requiring hand therapy…
- Trial name
- NCT03241628
- Testing
- Dressing Glove
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Osteoarthritis Finger, Surgery
Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint.
- Trial name
- NCT05980793
- Testing
- PIP joint denervation, Patient education plus exercise
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Trigger Finger
The Effects of a Structured Hand Exercise Program on Trigger Finger: A Randomized Controlled Trial
To explore the effectiveness of a structured hand exercise program as a conservative treatment for trigger finger.
- Trial name
- NCT06911762
- Testing
- Exercise
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The Hong Kong Polytechnic University
Appendicitis, Surgical Site Infection
Transumbilical Laparoscopic Appendectomy
Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches.
- Trial name
- NCT06177418
- Testing
- Transumbilical laparoscopic appendectomy + Glove finger technique, Standard transumbilical laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Undernutrition, Elderly Person
Finger Food, Pleasure at Your Fingertips: Randomized Pilot Study, Open-label and Parallel Groups
Food is available in easy-to-grip bites that allow residents in care settings to use their fingers for food. This new way of eating can help limit weight loss, increase food intake, gain independence and improve the enjoyment of…
- Trial name
- PLAID (NCT05389098)
- Testing
- Hand-Eating, Control
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Motor Recovery
BreEStim for Post-Stroke Motor Recovery
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750551
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Stroke, Cervical Spinal Cord Injury
Motor Recovery Training for Hand and Digits in Stroke and SCI
This study will use evaluate a hand therapy device training isolated finger control with engaging video gaming technology to facilitate hand and digit recovery in patients with acute stroke and cervical spinal cord injury.
- Trial name
- NCT04688229
- Testing
- Hummingbird hand training device plus standard of care rehabilitation
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Pregnancy
Comparison of Beta-hCG Levels When Using Venous Puncture Blood and Peripheral Finger Stick Blood
The objective of his study is to quantitatively evaluate a patient's pregnancy status using their beta-hCG levels when using venipuncture blood vs peripheral blood.
- Trial name
- P-Beta-H (NCT07493720)
- Testing
- Beta-hCG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Laparoscopic Surgery, Operative Surgical Procedure
Blade Finger Technique for Safe Laparoscopic Entery
blade-finger technique is a new technique for laparoscopic access which is safe
- Conditions
- Laparoscopic Surgery, Operative Surgical Procedure, Insufflation, Safety Issues
- Trial name
- new technique (NCT05475470)
- Testing
- finger-blade technique, Hasson's technique, veress needle technique
- Where
- Egypt
- Volunteers
- 1,005 people
- Sponsor
- Zagazig University
Stenosing Tenosynovitis
Corticosteroid vs. Amniotic Fluid Injections in Patients With Trigger Finger
The proposed study aims to investigate whether amniotic fluid injections are a better alternative to corticosteroid injections as a conservative treatment for stenosing tenosynovitis.
- Trial name
- NCT03583151
- Testing
- Amniotic fluid injection, Steroid injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- J&M Shuler
Stroke With Hemiparesis
Transfer of Grasp Control Across Hands After Stroke
The purpose of this study is to examine if the strong hand can assist in the recovery of muscle function in the weak hand after a stroke.
- Trial name
- NCT00589368
- Testing
- Transfer of grasp control across hands
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Injection Site, Arthritis;Hand/Finger(S)
Evaluating Palpation Guided Injections in Trapeziometacarpal Arthritis
The objective of this study is to evaluate the accuracy of trapeziometacarpal injections using palpation alone. The importance of this study is one of education, cost containment, and decreased risk to the patient.
- Trial name
- NCT03147118
- Testing
- Arthrogram
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Prisma Health-Upstate
Fracture Finger
Buddy Taping Compared to Splint Immobilization for Displaced Paediatric Finger Fractures
Fracture immobilization with Buddy taping is not inferior to Splint immobilization for non-displaced extra-articular paediatric finger fractures. However, whether the same applies for reduced finger fractures is unclear.
- Trial name
- NCT04068935
- Testing
- fracture immobilization after reduction of displaced finger fractures
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Children's Hospital, Zurich
Pre-Eclampsia
Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements
The purpose of this study is to compare the feasibility and accuracy of two methods of non-invasive hemodynamic assessments - bioreactance as assessed by non-invasive cardiac output monitoring (NICOM; Cheetah Medical) and pulse…
- Trial name
- NCT05299229
- Testing
- Echocardiogrpahy and non-invasive monitoring
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Stroke
Effects of Intensive Training on Reocvery of Fingers Dexterity Following Stroke
The investigators aim to test whether intensive training of finger individuation during the sensitive window of the subacute phases can lead to a clinically-meaningful recovery of dexterous movement in stroke patients.
- Trial name
- NCT04229329
- Testing
- Intensive Finger Individuation Therapy, Intensive non-directed finger movement therapy
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Loewenstein Hospital
HIV-1-infection
Long-term Follow-up of HIV Subjects Exposed to SB-728-T or SB-728mR-T
Long-term follow-up of HIV-infected subjects who received SB-728-T or SB-728mR-T. Enrolling subjects will be followed for a total of 12 years.
- Trial name
- NCT04201782
- Testing
- There are no disallowed treatments
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Sangamo Therapeutics
HIV Infections
CCR5-modified CD4+ T Cells for HIV Infection
A Comparative Study of Autologous CD4+ T Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 versus ex vivo Expanded Unmodified Autologous CD4+ T Cells in Treated HIV-1 Infected Subjects
- Trial name
- TRAILBLAZER (NCT03666871)
- Testing
- SB-728-T, Expanded unmodified autologous CD4+ T cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Amputation; Traumatic, Hand
To Evaluate the Clinical Impact of the Point Powered System
The objective of this study is to evaluate the efficacy of the Point Powered system as compared to the patient's standard-of-care treatment.
- Trial name
- NCT07135947
- Testing
- Point Powered partial hand prosthetic system
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Point Designs