Clinical trials: Firefighters, open to volunteers
Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy
Pre-malignant States to Hematologic Malignancies in Firefighters
The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic…
- Conditions
- Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia
- Trial name
- NCT06870760
- Testing
- Monoclonal Gammopathy, Complete Blood Count with differential (CBC w/ diff), Clonal hematopoiesis (CHIP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Firefighters
PeerOnCall: Implementing and Evaluating App-Based Peer Support in Canadian Fire Services
The goal of this clinical trial is to test how best to implement a mobile peer support app called PeerOnCall in Canadian fire services. The main questions it aims to answer are: 1.
- Trial name
- NCT07199387
- Testing
- App Users (Structured Implementation), App Users (Standard Implementation)
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cancer
Multi-Cancer Early Detection (MCED) of Firefighters
This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.
- Trial name
- NCT05780957
- Testing
- MCED
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Sleep Disorder
Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ...
The investigators have shown that sleep health education and sleep disorders screening improve health and safety of employees. There is potential to increase the benefits of the sleep health education and screening program if…
- Trial name
- NCT04519177
- Testing
- Sleep Health Education Program (SHEP)
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Toxicant Exposure, Firefighter
Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)
This randomized, placebo-controlled crossover trial will test the feasibility and acceptability of using colesevelam in male firefighters with high per- and polyfluoroalkyl substances (PFAS) exposure.
- Conditions
- Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
- Trial name
- ENGINE (NCT07226440)
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Mental Health, Physical Performance
A Multi-language Smartphone-based Healthy Lifestyle Intervention for Firefighters
The goal of this cluster randomized controlled trial is to evaluate the effects of a smartphone-based Healthy Lifestyle (HLS) intervention on firefighters' mental and physical health in firefighters in Tainan, Taiwan.
- Conditions
- Mental Health, Physical Performance, Cardiovascular Health, Lifestyle Intervention
- Trial name
- NCT06862427
- Testing
- Healthy Lifestyle Application (Traditional Chinese Version)
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cancer
Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System
The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect…
- Trial name
- NCT06931561
- Testing
- Whole Body MRI, Whole Body Ultrasound, MCD Assay
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Inova Health Care Services
Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption
Self-administered Neurostimulation Intervention for Firefighter Traumatic Stress to Reduce Alcohol Use: Pilot Study
The goal of this clinical trial is to evaluate the feasibility, acceptability, and appropriateness of a transcutaneous auricular neurostimulation (tAN) protocol in firefighters who engage in heavy drinking, have at least a mild…
- Conditions
- Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption, Alcohol Use Disorder (AUD)
- Trial name
- SANI-T (NCT07868055)
- Testing
- Transcutaneous auricular neurostimulation (tAN)
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Firefighters' Mental Health
F.I.R.E.- Fighters With Focus, Intention, Regulation and Engagement
Firefighters are routinely exposed to potentially traumatic events, making them vulnerable to debilitating mental health problems.
- Trial name
- NCT07484711
- Testing
- FIRE
- Where
- Portugal
- Volunteers
- 53 people
- Sponsor
- University of Coimbra
Cognitive Behavioral Therapy, Sleep Initiation and Maintenance Disorders
Evaluating Worksite Sleep Health Coaching in Firefighters: The Sleep Assistance for Firefighters Study
Insufficient sleep is a significant public health issue, particularly affecting shift workers like firefighters, nearly half of whom report short or poor-quality sleep, with 35-40% screening positive for sleep disorders.
- Conditions
- Cognitive Behavioral Therapy, Sleep Initiation and Maintenance Disorders, Sleep Deprivation, Sleep Disorders, Intrinsic
- Trial name
- SAFFIRE (NCT06684444)
- Testing
- firefighter Sleep Health Coaching Intervention (ffSHC), Control (Minimally Enhanced Usual Care)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Arizona
Obesity and Obesity-related Medical Conditions
"F!reF!ghterF!t": Lifestyle Coaching Interventions for Obese Firefighters (FireFit)
Our goal is to explore the effectiveness of 9- month lifestyle medicine based coaching intervention (individual and group coaching) versus control (usual care/ written health instructions).
- Trial name
- FireFit (NCT06890975)
- Testing
- Lifestyle Coaching
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cambridge Health Alliance
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Hydration Status
The Impact of Self-assessment on Hydration
The studies objective is to assess the efficacy of hydration education and the use of a self-assessment worksheet vs. a no-intervention control on improving fluid intake and hydration status in underhydrated wildland firefighters…
- Trial name
- NCT06954909
- Testing
- Hydration education and self-assessment
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Sleep Health, Stress
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
The purpose of this pilot study is to examine the feasibility and acceptability of an app-based sleep program designed to help firefighters improve their sleep.
- Conditions
- Sleep Health, Stress, Anxiety, Physical Activity
- Trial name
- NCT07477184
- Testing
- Sleep enhancement intervention, Standard of Care (Investigator Choice)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Anosmia, Chronic Obstructive Pulmonary Disease
Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)
Background: Exposure to smoke increases the risk of many diseases. People can be exposed to dangerous levels of smoke during wildfires. Also, smoke from fires that burn manmade materials may contain toxic chemicals.
- Conditions
- Anosmia, Chronic Obstructive Pulmonary Disease, Hyposmia, Chronic Rhinosinusitis
- Trial name
- NCT07867184
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Observational Study of Exposure to Environmental Toxicants Among Firefighters
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
- Trial name
- NCT05643014
- Testing
- Sample collection
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Cancer, Diet Habits
Dietary Patterns Following a Firefighter Nutrition Education Programme
Firefighters may be at increased risk of poor dietary habits due to nature of shift work, extended duty periods, and reliance on food available within fire station environments.
- Trial name
- RESCUE (NCT07687849)
- Testing
- RESCUE Nutrition Education Programme
- Where
- United Kingdom
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Avon Fire and Rescue Service
Cancer
Occupational Exposures Among Firefighters
This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.
- Trial name
- NCT06173843
- Testing
- PFAS / heavy metal testing, exposures
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
Cancer Prevention, Firefighters
Behavior and Risk Awareness Through Video Education for Firefighters
The goal of this clinical trial is to evaluate the impact of short documentary-style videos to educate and inspire firefighters to take safety measures to prevent cancer incidence and mortality.
- Trial name
- BRAVE (NCT07494617)
- Testing
- Video 1, Video 2, Video 3
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, Davis