Clinical trials: First Pregnancy
Preterm Infant, Umbilical Cord Milking
Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
The investigators hypothesise that intact umbilical cord milking (I-UCM) will reduce neonatal morbidity and improve long term neurodevelopmental outcome in very preterm infants.
- Trial name
- Cord-milking (NCT03200301)
- Testing
- Intact Umbilical Cord Milking
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Chronic Kidney Diseases, Left Ventricular Systolic Dysfunction
Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography
The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD).
- Trial name
- NCT06221891
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Cholestasis of Pregnancy
Genetic Polymorphisms of ABCB11 and ABCB4 in Women With Intrahepatic Cholestasis of Pregnancy (ICP) and in Their First Degree Relatives
To assess the occurrence of 11 SNP's in ABCB11 and ABCB4 genes in Greek women with ICP compared with healthy pregnant women. Moreover, these genetic polymorphisms will be examined in their first-degree relatives.
- Trial name
- NCT04281082
- Testing
- ursofalk
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Pregnancy
PLAC1 in Reproduction
The PLAC1 gene is a recently described X-linked gene that maps to a region of the X chromosome thought to be important for normal fetal and placental development.
- Trial name
- NCT01277848
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Incomplete Abortion
400mcg Sublingual Misoprostol as First Line Treatment
Women presenting with incomplete abortion and eligible for treatment with misoprostol were offered 400mcg sublingual misoprostol for treatment.
- Trial name
- NCT01939457
- Testing
- Misoprostol
- Where
- Senegal
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Chronic Kidney Disease(CKD), Genetic Kidney Disease
Genomic First Testing in Chronic Kidney Disease
This multi-center study examines the role of genetic testing in patients with chronic kidney disease (CKD) who are identified as being at risk for genetic kidney disease, based on Ontario Health's Provincial Genetic Program…
- Trial name
- NCT06794567
- Testing
- Genetic Testing
- Where
- Canada
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Dervla Connaughton
Threatened Miscarriage in First Trimester
Value of CA125 and Yolk Sac Morphology in Prediction of Pregnancy Outcome in Threatened Miscarriage
evaluation of serum CA125 level and yolk sac morphology in women with threatened miscarriage is very important to predict pregnancy outcome
- Trial name
- NCT03320213
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Miscarriage, Preterm Birth
Progesterone for the Prevention of Miscarriage and Preterm Birth in Women With First Trimester Bleeding: PREEMPT Trial
Miscarriages and preterm births are common and serious events affecting women, families, and healthcare systems on many levels. One of the risk factors for miscarriage and preterm birth is bleeding in the first trimester of…
- Trial name
- NCT02145767
- Testing
- Progesterone
- Where
- 7 sites in Canada
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Preeclampsia, Gestational Hypertension
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
Preeclampsia causes devastating maternal and neonatal morbidity and mortality with a high recurrence risk and a rapid, occult progression to cardiovascular disease after delivery.
- Conditions
- Preeclampsia, Gestational Hypertension, Hypertension, Obesity
- Trial name
- HH4NM (NCT03749746)
- Testing
- Home Blood Pressure Monitoring, Heart Health 4 New Moms, Usual care
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
First Trimester Pregnancy
Comparative Study of Learning Curve for First Trimester Fetal Anomaly Scan
Ultrasound scans during first trimester are more difficult than routine mid-trimester ultrasound scans. Practice guidelines for first trimester fetal ultrasound scans have been provided by the International Society of Ultrasound…
- Trial name
- NCT04707456
- Testing
- Training operator
- Where
- Thailand
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Suturing of Rectus Muscle at Cesarean Section
The Effect of Rectus Muscle Re-approximation at Cesarean Delivery on Postoperative Pain
The Effect of Rectus Muscle Re-approximation on Postoperative Pain Among Primigravida Singleton Pregnancies Who Underwent Elective Cesarean Section: A Randomized Prospective Trial.
- Trial name
- NCT05260970
- Testing
- Rectus muscle reapproximation at cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Labour Duration, Primigravida
Valethamate Bromide Versus Hyoscine Butyl Bromide in Reducing Labour Duration Among Primigravida
Labour is a physiological process that enables the natural delivery of fetus, placenta and membranes after the age of viability.
- Trial name
- NCT07474350
- Testing
- Valethamate Bromide, Hyoscine butylbromide, Sterile water
- Where
- Nigeria
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Ovarian Cancer, Sentinel Lymph Node
Mapping Sentinel Lymph Node in Initial Stages of Ovarian Cancer
Epithelial ovarian cancer (EOC) diagnosed in the initial stage (stage I-II) require complete staging surgery to histologically assess the possible existence of peritoneal or lymph node disease.
- Trial name
- MELISA (NCT05184140)
- Testing
- Sentinel node detection
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Pregnancy Related
The Effect of Mindfulness-Based Web-Based Stress Reduction Program Applied to Primigravidas on Perceived Stress Level in Pregnancy, Birth Self-Efficacy and Prenatal Attachment
The aim of this study is to investigate the effect of a mindfulness-based web-based stress reduction program applied to primigravidas on perceived stress level in pregnancy, birth self-efficacy and prenatal attachment.
- Trial name
- NCT06316518
- Testing
- mindfulness group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Fetal Conditions
Early Pregnancy Ultrasound Parameters Including Corpus Luteum Doppler in Prediction of First Trimester Pregnancy Outcome in Spontaneous Pregnancies.
The synthesis of progesterone by corpus luteum is extremely important for the maintenance of normal pregnancy in the first seven weeks.
- Trial name
- NCT07204028
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Disease
Initial Study With the CNDS Advanced Cervical Scan to Recalibrate Spectral Data for Use in Future Screening Studies
The purpose of this study is to evaluate whether fluorescence and reflectance spectroscopy can improve the ability to detect the presence of premalignant lesions on the cervix.
- Trial name
- Spectral (NCT02217215)
- Testing
- CNDS Advanced Cervical Scan
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Guided Therapeutics
Preterm, Breastfeeding
Breastfeeding and Bottle Feeding: Impact on Preterm Infants' Physiology and Feeding Performance
The goal of this clinical trial is to evaluate the effect of breastfeeding on the infant's test weight and physiological characteristics (oxygen saturation and heart rate) in preterm infants in the Neonatal Intensive Care Unit…
- Conditions
- Preterm, Breastfeeding, Bottlefeeding, Premature
- Trial name
- NCT05651035
- Testing
- oral feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Undesired Pregnancy
Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)
The main objective of this study is to determine the equivalency of oral conscious sedation and intravenous conscious sedation for first trimester surgical abortion.
- Trial name
- NCT00337792
- Testing
- oxycodone + lorazepam versus fentanyl + midazolam
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Pregnancy Early
Assessing Gestational Age in First Trimester Pregnancies Using Ultrasound
The objective of this study is to assess equivalency of the transabdominal Clarius handheld wifi C3 ultrasound (which uses Bluetooth to locate the ipad Mini 5 and then uses wifi direct to show the images) to the current standard…
- Trial name
- NCT03957200
- Where
- 2 sites in Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Preterm Birth, Low Birth Weight
Description and Comparison of Biological Vulnerability in Small Vulnerable Newborns Versus Healthy Community Controls in Urban Burkina Faso
The aim of the DenBalo study is to apply integrated multi-omics methods to examine the biological mechanisms underlying this vulnerability in Small Vulnerable Newborns (SVNs) in LMICs, with the ultimate goal of identifying…
- Conditions
- Preterm Birth, Low Birth Weight, Small for Gestational Age at Delivery
- Trial name
- DenBalo (NCT05730569)
- Where
- Burkina Faso
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent