Clinical trials: First Pregnancy
Surgical Anxiety Scale for Adult Patients, Surgical Fear Scale
Effect of Artificial Intelligence-Based Education Before Planned Cesarean Section on Surgical Fear, Anxiety, and Postpartum Comfort Levels of Primigravida Women
This study was planned to determine the effect of artificial intelligence use before planned cesarean section on surgical fear, anxiety and postpartum comfort levels of primigravida women.
- Conditions
- Surgical Anxiety Scale for Adult Patients, Surgical Fear Scale, Postpartum Comfort Scale
- Trial name
- Education (NCT07419529)
- Testing
- individual education about cesarean surgery, about cesarean surgery using artificial intelligence, routine maintenance of the institution
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Preterm Birth, Low Birth Weight
Description and Comparison of Biological Vulnerability in Small Vulnerable Newborns Versus Healthy Community Controls in Urban Burkina Faso
The aim of the DenBalo study is to apply integrated multi-omics methods to examine the biological mechanisms underlying this vulnerability in Small Vulnerable Newborns (SVNs) in LMICs, with the ultimate goal of identifying…
- Conditions
- Preterm Birth, Low Birth Weight, Small for Gestational Age at Delivery
- Trial name
- DenBalo (NCT05730569)
- Where
- Burkina Faso
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infections, Streptococcal
Study to Evaluate the Safety and Immunogenicity of a 10-valent Pneumococcal Conjugate Vaccine in Preterm Infants
This study aims to evaluate the safety, reactogenicity and immunogenicity of GlaxoSmithKline (GSK) Biologicals´ 10-valent pneumococcal conjugate vaccine when co-administered with diphtheria, tetanus, acellular pertussis-hepatitis…
- Trial name
- NCT00390910
- Testing
- Pneumococcal conjugate vaccine GSK1024850A, Infanrix hexa
- Where
- 8 sites in Greece, Spain
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Medical Abortion, Fetus
Reducing the Need for In-Clinic Follow-Up for Medical Abortion in Moldova and Uzbekistan
The purpose of this study is to determine whether an alternative method of follow-up after medical abortion is acceptable and feasible for use in Moldova and Uzbekistan.
- Trial name
- NCT01410266
- Testing
- Alternative follow-up
- Where
- 7 sites in Moldova, Uzbekistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Fecal Incontinence, Urinary Incontinence
First Time Mothers and Anal Incontinence Six Years Postpartum
Previous studies show that incontinence is relatively common during pregnancy and after delivery. Experiencing incontinence during pregnancy or in the first year after delivery increases the risk of long term incontinence.
- Conditions
- Fecal Incontinence, Urinary Incontinence, Quality of Life
- Trial name
- FiTMAI6 (NCT02792244)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Preeclampsia
A Study to Evaluate the Use of Placenta Protein 13 (PP13) in the First Trimester of Pregnancy as a Diagnostic Aiding Tool in the Assessment of the Risk for Developing Preeclampsia in Women With Low and Unknown Risk
The purpose of this study is to evaluate whether it is possible to detect changes in the concentration of PP13 in the blood of pregnant women who may go on to develop the complication of preeclampsia later on in the pregnancy…
- Trial name
- NCT00572793
- Where
- United States
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Carl Weiner, MD
Maternal-Fetal Relations, Birth, First
Effects of Pelvic Exercises on Birth and Incontinence
The Effect of Pelvic Floor Exercises During Pregnancy on Obstetric Outcomes and Urinary Incontinence: A Prospective Randomized Controlled Trial
- Conditions
- Maternal-Fetal Relations, Birth, First, Incontinence, Urinary, Pelvic Floor Disorders
- Trial name
- NCT07268014
- Testing
- Pelvic Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Selcuk University
PREGNANCY
Induction Versus Expectant Management With Abnormal Maternal Biochemical Markers
Induction of labor at term versus expectant management among women with abnormal maternal biochemical markers. A randomized controlled trial
- Trial name
- NCT02754635
- Testing
- Induction of labour, Expectant management
- Where
- Israel
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Neurological Development After Exposition to an Antenatal Nuchal Translucency
Follow up of Neurologic Development of Children Who Presented at the First Trimester of Pregnancy an Isolated Nuchal Anomaly With Normal Karyotype
Prospective, multicenter study following for 2 years, 250 children who presented during the first trimester of pregnancy an isolated nuchal translucency over the 95th percentile of Nicolaïdes Curves on ultrasound and comparing…
- Trial name
- EDEN (NCT02223936)
- Testing
- group exposed, Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Augmentation, Induction
The Effect of Consumption of Date Fruit and Nipple Stimulation in Late Pregnancy
The study was conducted to determine the effect of consumption of date fruit and nipple stimulation on labor. The samples were applied to pregnant women satisfying the research criteria in a state hospital in Istanbul between…
- Conditions
- Augmentation, Induction, Labor, Stimulation, Self
- Trial name
- NCT06280911
- Testing
- Date Fruit group, Nipple group
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Labor Pain
Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
The study aims to investigate the effects of a combination of Lamaze breathing exercises and backside massage on the labor experiences of primigravidae in Pakistan.
- Trial name
- NCT06304311
- Testing
- Routine Obstetrics care & Lamaze breathing techniques and backside massage, Routine obstetrics care
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Herpes Simplex
A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes
The purpose of this first-time-in-human (FTiH) study is to evaluate the reactogenicity, safety, immune response, and efficacy of an investigational herpes simplex virus (HSV)-targeted immunotherapy (TI).
- Trial name
- NCT05298254
- Testing
- Non-adjuvanted HSV formulation 1, Non-adjuvanted HSV formulation 2, Non-adjuvanted HSV formulation 3
- Where
- 30 sites in United States, Australia and 6 more
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Missed Abortion
Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
The purpose of this study is to determine the effectiveness of buccal misoprostol and comparing this with vaginal route of the same drug.
- Trial name
- NCT00892229
- Testing
- Misoprostol (given buccally), Misoprostol (given vaginally)
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Miscarriage in First Trimester
Angular Pregnancy - Ultrasound Definition and Correlation With Clinical Outcomes
The aim of this study is to establish clinically meaningful ultrasound-based diagnostic criteria for AP. To this end, the investigators will prospectively collect clinical and ultrasound data from early intrauterine pregnancies…
- Trial name
- NCT06262373
- Testing
- Ultrasound
- Where
- United Kingdom
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Obstetric Labor Complications, Preeclampsia
Platelet Count Trends in Pre-eclamptic Parturients
Thrombocytopenia (platelet count < 100,000/mL) occurs in approximately 15% of women with preeclampsia. Neuraxial analgesia is contraindicated in parturients with a coagulopathy; therefore, the platelet count(PC) is routinely…
- Conditions
- Obstetric Labor Complications, Preeclampsia, Thrombocytopenia
- Trial name
- NCT00787241
- Where
- United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy, Skin to Skin Contact
Skin-to Skin Contact on Newborn Temperature
This study will compare standard methods of stabilizing a newborn's temperature after birth with mother-infant skin-to-skin contact for stabilizing newborn temperature.
- Trial name
- NCT02143193
- Testing
- Skin-to-Skin Contact
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Rachel Baker
Abortifacient Agents, Nonsteroidal, Abortion, Incomplete
Misoprostol for Non-Viable Pregnancies
The purpose of this study is to examine the effectiveness of Misoprostol (Cytotec; GD Searle and Co., Chicago, IL) for the management of non-viable first trimester pregnancies.
- Conditions
- Abortifacient Agents, Nonsteroidal, Abortion, Incomplete, Misoprostol, Pregnancy
- Trial name
- NCT00426491
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Iron Deficiency Anemia
Iron Metabolism Parameters At First Trimester and preGnancy outcomE
Iron deficiency anemia is the leading cause of anemia during pregnancy, which can still reach 10 to 20% of pregnant women in developed countries, with potentially serious consequences for the child.
- Trial name
- IMAGE (NCT03176147)
- Testing
- Iron deficiency anemia
- Where
- France
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand