Clinical trials: Fistula;Rectal
Anal Fistula
Treatment of Perirectal Fistula With Cutting Seton vs. Collagen Plug
The purpose of this study is to determine if the collagen plug method heals perirectal fistulae as well as the conventional seton method.
- Trial name
- NCT00450671
- Testing
- Collagen Plug Placement, Seton placement
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Southern California
Anal Fistula
Imaging Template for Reporting Anal Fistula
Magnetic resonance imaging (MRI) is the most used diagnostic tool for pre-operative assessment of anal fistula. However, there is lack of standardization in reporting this investigation.
- Trial name
- ITRAF (NCT04541238)
- Testing
- MRI
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Treviso Regional Hospital
Perianal Abscess, Anal Fistulas
Multicenter Study for Diagnosis and Treatment of Perianal Abscesses
Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife.
- Conditions
- Perianal Abscess, Anal Fistulas, Incontinence
- Trial name
- NCT02306382
- Testing
- Perianal abscess drainage, 3D ultrasonography
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Umeå
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Transsphincteric Anal Fistula
Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.
78 patients with transsphincteric fistula allocated into two groups group A underwent LIFT group B u nderwent fistulectomy , comparison between the outcome og both procedures
- Trial name
- professor (NCT04351074)
- Testing
- LIFT, fistulectomy
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Zagazig University
Crohn's Fistula
Darvadstrocel for Crohn's Fistula in the Realworld
Background Perianal fistula may affect 15-50% of patients with Crohn's disease (CD). Treatment is complex, requiring a multidisciplinary approach.
- Trial name
- NCT05742100
- Testing
- Darvadstrocel
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Dolores Herreros Marcos
Anal Fistulas
Seton or Glue for Trans-sphincteric Anal Fistulas
Surgical treatment of perianal fistulas frequently affects fecal continence. Sphincter saving techniques like loose or cutting seton and fistulectomy with advancement of an endorectal flap have been advocated to minimize the risk…
- Trial name
- NCT00929630
- Testing
- transsphincteric Seton positioning, glue (Tissucol) treatment, Fistula closing with biological glue
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Fissure;Anal, Fistula;Rectal
Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery
Double-blinded multicenter randomized clinical trial to evaluate the efficacy and safety of CLIFE2 (lidocaine, referred as treatment A) respect CLIFE1 (lidocaine plus diclofenac, referred as treatment B) in benign anorectal…
- Conditions
- Fissure;Anal, Fistula;Rectal, Hemorrhoids
- Trial name
- NCT02961855
- Testing
- anesthesics plus antiinflammatory, CLIFE1, local anesthesics, CLIFE2
- Volunteers
- 120 people
- Sponsor
- Hospital de Viladecans
Fistula-In-Ano, Anal Fistula
Treatment of Anal Fistula With Lasercoagulation
The purpose of this study is to determine whether treatment with laser coagulation is an effective and safe treatment option for patients with anal fistula
- Trial name
- NCT03017898
- Testing
- Laser Coagulation
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Region Skane
Fistula in Ano
Compound Phellodendron Decoction May Promote Wound Healing After Anal Fistulotomy
Sitz-bath therapy with Chinese medicine has significant advantages in the management of postoperative wounds of anal fistula. This method not only ensures safety, efficacy, and cost-effectiveness, but also simplifies application.
- Trial name
- CPD (NCT06663527)
- Testing
- Fumigating-washing Therapy With CPD
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Anal Fistula, Crohn Disease
Management of Anal Fistula of Crohn Disease
The management of anal fistula in Crohn Disease is complex. In aim to obtain the healing of the anal fistula, different approaches can be proposed but the best strategy is not yet determined.
- Trial name
- FISTUCROHN (NCT03878498)
- Testing
- therapeutic management
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Rennes University Hospital
Anal Fistula, Treatment
The Efficacy of Human Acellular Dermal Matrix in the Treatment of Anal Fistula
The purpose of this study is to determine whether human acellular dermal matrix plug is effective in the treatment of anal fistula
- Conditions
- Anal Fistula, Treatment, Postoperative Complications, Acellular Dermal Matrix
- Trial name
- NCT00951002
- Testing
- acellular dermal matrix plug
- Where
- 13 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Zhen Jun Wang
Hemorrhoids, Fistula
Comparison Study of the Effect of Enema in Anal Surgery
To evaluate whether receiving enema before anal surgery or not affects the postoperative recovery and complications.
- Trial name
- NCT05602987
- Testing
- enema, no enema
- Where
- Taiwan
- Volunteers
- 282 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Anal Fistula
Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain
comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative…
- Trial name
- NCT04155905
- Testing
- fistulotomy and marsupialization of wound edges, fistulotomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Healing of the Wound After Rectovaginal Fistula Surgery
the Method of Cotton Padding Promoting the Rectovaginal Fistula Surgery
The method of Cotton Padding (mCP) was summarized by combining with many years clinical experience and the traditional ancient books.The mCP could be used in Rectovaginal Fistula (RVF) post operation effectively,in order to…
- Trial name
- NCT05138965
- Testing
- the mCP with alginates dressing, only alginates dressing
- Where
- 3 sites in China
- Volunteers
- 20 people
- Sponsor
- China Academy of Chinese Medical Sciences
Rectal Fistula
Anal Fistula Repair With Platelet-rich Plasma
Anal fistula is a very common disease with a high impact on life quality. The only commonly accepted treatment option is surgery.
- Trial name
- Aurora (NCT02678936)
- Testing
- PRP
- Where
- Switzerland
- Sponsor
- University Hospital, Basel, Switzerland
Fistula in Ano
Long Term Outcomes After Surgery for Anal Fistula
Anal fistula is a common condition with a wide variety of clinical presentations, which can make evaluation and treatment challenging and surgical outcomes uncertain.
- Trial name
- NCT04588701
- Testing
- surgical procedures commonly done for anal fistula
- Volunteers
- 483 people
- Sponsor
- University of Michigan
Anal Fistula
Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy
Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical…
- Trial name
- NCT03096522
- Testing
- Phenytoin 2% spray, Anal fistulotomy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Fistula in Ano, Crohn Disease
Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease
Crohn's disease is a chronic inflammatory condition that can affect any part of the bowel which can be controlled by a combination of medical and surgical treatments but cannot be cured.
- Trial name
- NCT06822686
- Testing
- Harvest and injection of stem cells
- Sponsor
- Oxford University Hospitals NHS Trust
Anal Fistula
E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas
The purpose of this study is to determine if endothelial cells derived from human umbilical vein are safe for use in conjunction with fistulotomy for the treatment of simple anal fistulas.
- Trial name
- NCT04190862
- Testing
- E-CEL UVEC
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Weill Medical College of Cornell University